A subset of histamine H4 receptor antagonists prevents B lymphocyte proliferation induced by BCR/TLR9 engagement or EBV infection.

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Title: A subset of histamine H4 receptor antagonists prevents B lymphocyte proliferation induced by BCR/TLR9 engagement or EBV infection.
Authors: Roy M; Hormæ Pharma, Villeurbanne, France. Electronic address: marlene.lucie.roy@gmail.com., Bardel E; Lymphoma Immuno Biology Team, Centre International de Recherche en Infectiologie, INSERM U1111-CNRS UMR5308, Faculté de Médecine Lyon-Sud, Université Claude Bernard Lyon I-ENS de Lyon, Lyon, France., Gromolard L; Viral Infection Metabolism and Immunity Team, Centre International de Recherche en Infectiologie, Univ Lyon, Inserm, U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, ENS de Lyon, Lyon, France., Chatonnet F; Lymphoma Immuno Biology Team, Centre International de Recherche en Infectiologie, INSERM U1111-CNRS UMR5308, Faculté de Médecine Lyon-Sud, Université Claude Bernard Lyon I-ENS de Lyon, Lyon, France., Besson-Pointeau L; Viral Infection Metabolism and Immunity Team, Centre International de Recherche en Infectiologie, Univ Lyon, Inserm, U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, ENS de Lyon, Lyon, France., Le Briand N; Hormæ Pharma, Villeurbanne, France., Jacquemin C; Viral Infection Metabolism and Immunity Team, Centre International de Recherche en Infectiologie, Univ Lyon, Inserm, U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, ENS de Lyon, Lyon, France., Perrin-Cocon L; Viral Infection Metabolism and Immunity Team, Centre International de Recherche en Infectiologie, Univ Lyon, Inserm, U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, ENS de Lyon, Lyon, France., Thaunat O; IMmunopAtholoGy and InNovATive ImmunointerventiON in transplantation (IMAGINATION) team, Centre International de Recherche en Infectiologie, Univ Lyon, Inserm, U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, ENS de Lyon, Lyon, France; Hospices Civils de Lyon, Edouard Herriot Hospital, Department of Transplantation, Nephrology and Clinical Immunology, Lyon, France., Fusil F; Lymphoma Immuno Biology Team, Centre International de Recherche en Infectiologie, INSERM U1111-CNRS UMR5308, Faculté de Médecine Lyon-Sud, Université Claude Bernard Lyon I-ENS de Lyon, Lyon, France; IMmunopAtholoGy and InNovATive ImmunointerventiON in transplantation (IMAGINATION) team, Centre International de Recherche en Infectiologie, Univ Lyon, Inserm, U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, ENS de Lyon, Lyon, France., Roche D; Edelris, Lyon, France., Chebel A; Lymphoma Immuno Biology Team, Centre International de Recherche en Infectiologie, INSERM U1111-CNRS UMR5308, Faculté de Médecine Lyon-Sud, Université Claude Bernard Lyon I-ENS de Lyon, Lyon, France., Traverse-Glehen A; Lymphoma Immuno Biology Team, Centre International de Recherche en Infectiologie, INSERM U1111-CNRS UMR5308, Faculté de Médecine Lyon-Sud, Université Claude Bernard Lyon I-ENS de Lyon, Lyon, France; Hospices Civils de Lyon, Hématopathologie, Hôpital Lyon Sud, France., Lotteau V; Laboratoire P4 INSERM-Jean Mérieux, Lyon, France., Genestier L; Lymphoma Immuno Biology Team, Centre International de Recherche en Infectiologie, INSERM U1111-CNRS UMR5308, Faculté de Médecine Lyon-Sud, Université Claude Bernard Lyon I-ENS de Lyon, Lyon, France., Vidalain PO; Viral Infection Metabolism and Immunity Team, Centre International de Recherche en Infectiologie, Univ Lyon, Inserm, U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, ENS de Lyon, Lyon, France., André P; Hormæ Pharma, Villeurbanne, France; Viral Infection Metabolism and Immunity Team, Centre International de Recherche en Infectiologie, Univ Lyon, Inserm, U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, ENS de Lyon, Lyon, France. Electronic address: patrice.andre@inserm.fr.
Source: Antiviral research [Antiviral Res] 2026 Jul; Vol. 251, pp. 106438. Date of Electronic Publication: 2026 May 15.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 8109699 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-9096 (Electronic) Linking ISSN: 01663542 NLM ISO Abbreviation: Antiviral Res Subsets: MEDLINE
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  Data: A subset of histamine H4 receptor antagonists prevents B lymphocyte proliferation induced by BCR/TLR9 engagement or EBV infection.
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  Data: <searchLink fieldCode="AU" term="%22Roy+M%22">Roy M</searchLink>; Hormæ Pharma, Villeurbanne, France. Electronic address: marlene.lucie.roy@gmail.com.<br /><searchLink fieldCode="AU" term="%22Bardel+E%22">Bardel E</searchLink>; Lymphoma Immuno Biology Team, Centre International de Recherche en Infectiologie, INSERM U1111-CNRS UMR5308, Faculté de Médecine Lyon-Sud, Université Claude Bernard Lyon I-ENS de Lyon, Lyon, France.<br /><searchLink fieldCode="AU" term="%22Gromolard+L%22">Gromolard L</searchLink>; Viral Infection Metabolism and Immunity Team, Centre International de Recherche en Infectiologie, Univ Lyon, Inserm, U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, ENS de Lyon, Lyon, France.<br /><searchLink fieldCode="AU" term="%22Chatonnet+F%22">Chatonnet F</searchLink>; Lymphoma Immuno Biology Team, Centre International de Recherche en Infectiologie, INSERM U1111-CNRS UMR5308, Faculté de Médecine Lyon-Sud, Université Claude Bernard Lyon I-ENS de Lyon, Lyon, France.<br /><searchLink fieldCode="AU" term="%22Besson-Pointeau+L%22">Besson-Pointeau L</searchLink>; Viral Infection Metabolism and Immunity Team, Centre International de Recherche en Infectiologie, Univ Lyon, Inserm, U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, ENS de Lyon, Lyon, France.<br /><searchLink fieldCode="AU" term="%22Le+Briand+N%22">Le Briand N</searchLink>; Hormæ Pharma, Villeurbanne, France.<br /><searchLink fieldCode="AU" term="%22Jacquemin+C%22">Jacquemin C</searchLink>; Viral Infection Metabolism and Immunity Team, Centre International de Recherche en Infectiologie, Univ Lyon, Inserm, U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, ENS de Lyon, Lyon, France.<br /><searchLink fieldCode="AU" term="%22Perrin-Cocon+L%22">Perrin-Cocon L</searchLink>; Viral Infection Metabolism and Immunity Team, Centre International de Recherche en Infectiologie, Univ Lyon, Inserm, U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, ENS de Lyon, Lyon, France.<br /><searchLink fieldCode="AU" term="%22Thaunat+O%22">Thaunat O</searchLink>; IMmunopAtholoGy and InNovATive ImmunointerventiON in transplantation (IMAGINATION) team, Centre International de Recherche en Infectiologie, Univ Lyon, Inserm, U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, ENS de Lyon, Lyon, France; Hospices Civils de Lyon, Edouard Herriot Hospital, Department of Transplantation, Nephrology and Clinical Immunology, Lyon, France.<br /><searchLink fieldCode="AU" term="%22Fusil+F%22">Fusil F</searchLink>; Lymphoma Immuno Biology Team, Centre International de Recherche en Infectiologie, INSERM U1111-CNRS UMR5308, Faculté de Médecine Lyon-Sud, Université Claude Bernard Lyon I-ENS de Lyon, Lyon, France; IMmunopAtholoGy and InNovATive ImmunointerventiON in transplantation (IMAGINATION) team, Centre International de Recherche en Infectiologie, Univ Lyon, Inserm, U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, ENS de Lyon, Lyon, France.<br /><searchLink fieldCode="AU" term="%22Roche+D%22">Roche D</searchLink>; Edelris, Lyon, France.<br /><searchLink fieldCode="AU" term="%22Chebel+A%22">Chebel A</searchLink>; Lymphoma Immuno Biology Team, Centre International de Recherche en Infectiologie, INSERM U1111-CNRS UMR5308, Faculté de Médecine Lyon-Sud, Université Claude Bernard Lyon I-ENS de Lyon, Lyon, France.<br /><searchLink fieldCode="AU" term="%22Traverse-Glehen+A%22">Traverse-Glehen A</searchLink>; Lymphoma Immuno Biology Team, Centre International de Recherche en Infectiologie, INSERM U1111-CNRS UMR5308, Faculté de Médecine Lyon-Sud, Université Claude Bernard Lyon I-ENS de Lyon, Lyon, France; Hospices Civils de Lyon, Hématopathologie, Hôpital Lyon Sud, France.<br /><searchLink fieldCode="AU" term="%22Lotteau+V%22">Lotteau V</searchLink>; Laboratoire P4 INSERM-Jean Mérieux, Lyon, France.<br /><searchLink fieldCode="AU" term="%22Genestier+L%22">Genestier L</searchLink>; Lymphoma Immuno Biology Team, Centre International de Recherche en Infectiologie, INSERM U1111-CNRS UMR5308, Faculté de Médecine Lyon-Sud, Université Claude Bernard Lyon I-ENS de Lyon, Lyon, France.<br /><searchLink fieldCode="AU" term="%22Vidalain+PO%22">Vidalain PO</searchLink>; Viral Infection Metabolism and Immunity Team, Centre International de Recherche en Infectiologie, Univ Lyon, Inserm, U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, ENS de Lyon, Lyon, France.<br /><searchLink fieldCode="AU" term="%22André+P%22">André P</searchLink>; Hormæ Pharma, Villeurbanne, France; Viral Infection Metabolism and Immunity Team, Centre International de Recherche en Infectiologie, Univ Lyon, Inserm, U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, ENS de Lyon, Lyon, France. Electronic address: patrice.andre@inserm.fr.
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