Flavonoid-rich extract of Cereus jamacaru: safety assessment and protective effects via NF-κB/MAPK modulation in an acute intestinal inflammation model.
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| Title: | Flavonoid-rich extract of Cereus jamacaru: safety assessment and protective effects via NF-κB/MAPK modulation in an acute intestinal inflammation model. |
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| Authors: | da Costa Melo NM; Research Group of Bioactive Natural Products, Health Sciences Center, Pharmacy Department, Federal University of Rio Grande do Norte, Natal, Rio Grande do Norte, Brazil; Postgraduate Program in Biochemistry and Molecular Biology, Biosciences Center, Federal University of Rio Grande Norte, Natal, Brazil; Postgraduate Program in Development and Technological Innovation in Medicines, Health Sciences Center, Natal, Rio Grande do Norte, Brazil. Electronic address: nadja.melo.094@ufrn.edu.br., de Souza Araújo DF; Health Sciences College of Trairi, Department of Nutrition, Federal University of Rio Grande do Norte, Santa Cruz, Brazil. Electronic address: daline.araujo@ufrn.br., Dantas-Medeiros R; Research Group of Bioactive Natural Products, Health Sciences Center, Pharmacy Department, Federal University of Rio Grande do Norte, Natal, Rio Grande do Norte, Brazil; Postgraduate Program in Development and Technological Innovation in Medicines, Health Sciences Center, Natal, Rio Grande do Norte, Brazil. Electronic address: renato.medeiros.071@ufrn.edu.br., da Silva VC; Research Group of Bioactive Natural Products, Health Sciences Center, Pharmacy Department, Federal University of Rio Grande do Norte, Natal, Rio Grande do Norte, Brazil; Postgraduate Program in Development and Technological Innovation in Medicines, Health Sciences Center, Natal, Rio Grande do Norte, Brazil. Electronic address: valeria.costa.098@ufrn.edu.br., de Aragão Tavares E; Health Sciences Center, Department of Pharmaceutical Sciences, Faculty of Pharmacy, Federal University of Rio Grande do Norte, Avenue General Gustavo Cordeiro de Farias, S/N, Petrópolis, Natal, Brazil; Research Group of Bioactive Natural Products, Health Sciences Center, Pharmacy Department, Federal University of Rio Grande do Norte, Natal, Rio Grande do Norte, Brazil. Electronic address: emanuella_ta@hotmail.com., Pinheiro FASD; Health Sciences Center, Department of Pharmaceutical Sciences, Faculty of Pharmacy, Federal University of Rio Grande do Norte, Avenue General Gustavo Cordeiro de Farias, S/N, Petrópolis, Natal, Brazil. Electronic address: ayrtonsennap@gmail.com., De Santis Ferreira L; Health Sciences Center, Department of Pharmaceutical Sciences, Faculty of Pharmacy, Federal University of Rio Grande do Norte, Avenue General Gustavo Cordeiro de Farias, S/N, Petrópolis, Natal, Brazil. Electronic address: leandro.ferreira@ufrn.br., Zanatta AC; Faculty of Pharmaceutical Science of Ribeirão Preto, University of São Paulo, USP, Ribeirão Preto, São Paulo, Brazil. Electronic address: anaczanatta@gmail.com., de Moura DR; Faculty of Pharmaceutical Science of Ribeirão Preto, University of São Paulo, USP, Ribeirão Preto, São Paulo, Brazil. Electronic address: diegomoura@usp.br., de Araujo AA; Department of Biophysics and Pharmacology, Biosciences Center, Federal University of Rio Grande do Norte, Natal, Brazil. Electronic address: aurigena.antunes@ufrn.br., de Araújo Júnior RF; Department of Biophysics and Pharmacology, Biosciences Center, Federal University of Rio Grande do Norte, Natal, Brazil. Electronic address: fernandes.araujo@ufrn.br., Guerra GCB; Department of Biophysics and Pharmacology, Biosciences Center, Federal University of Rio Grande do Norte, Natal, Brazil; Postgraduate Program in Biochemistry and Molecular Biology, Biosciences Center, Federal University of Rio Grande Norte, Natal, Brazil. Electronic address: gerlane.guerra@ufrn.br., Zucolotto SM; Health Sciences Center, Department of Pharmaceutical Sciences, Faculty of Pharmacy, Federal University of Rio Grande do Norte, Avenue General Gustavo Cordeiro de Farias, S/N, Petrópolis, Natal, Brazil; Research Group of Bioactive Natural Products, Health Sciences Center, Pharmacy Department, Federal University of Rio Grande do Norte, Natal, Rio Grande do Norte, Brazil; Postgraduate Program in Development and Technological Innovation in Medicines, Health Sciences Center, Natal, Rio Grande do Norte, Brazil. Electronic address: silvana.zucolotto@ufrn.br. |
| Source: | Journal of ethnopharmacology [J Ethnopharmacol] 2026 Oct 28; Vol. 369, pp. 121818. Date of Electronic Publication: 2026 May 14. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Elsevier Sequoia Country of Publication: Ireland NLM ID: 7903310 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-7573 (Electronic) Linking ISSN: 03788741 NLM ISO Abbreviation: J Ethnopharmacol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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