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Computational engineering of the polyester hydrolase PHL7 for efficient poly(ethylene terephthalate) degradation in biocatalytic recycling processes.

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Title: Computational engineering of the polyester hydrolase PHL7 for efficient poly(ethylene terephthalate) degradation in biocatalytic recycling processes.
Authors: Blázquez-Sánchez P; Institute for Drug Discovery, Leipzig University, Leipzig, Germany., Gunkel J; Institute for Drug Discovery, Leipzig University, Leipzig, Germany., Useini A; Institute for Drug Discovery, Leipzig University, Leipzig, Germany.; Institute of Bioanalytical Chemistry, Centre for Biotechnology and Biomedicine, Leipzig University, Leipzig, Germany., Zlobin A; Institute for Drug Discovery, Leipzig University, Leipzig, Germany., Zakary JD; Institute for Drug Discovery, Leipzig University, Leipzig, Germany., Schöler A; Institute for Drug Discovery, Leipzig University, Leipzig, Germany., Graefe N; Institute for Drug Discovery, Leipzig University, Leipzig, Germany.; Interdisciplinary Center for Bioinformatics, Leipzig University, Leipzig, Germany., Engelberger F; Institute for Drug Discovery, Leipzig University, Leipzig, Germany., Cantanhede F; Institute for Drug Discovery, Leipzig University, Leipzig, Germany., Frank R; Centre for Biotechnology and Biomedicine, Biochemical Cell Technology, Leipzig University, Leipzig, Germany., Zhao Z; Institute of Analytical Chemistry, Leipzig University, Leipzig, Germany., Zarei A; Institute of Analytical Chemistry, Leipzig University, Leipzig, Germany., Butenschön E; Institute of Analytical Chemistry, Leipzig University, Leipzig, Germany., Matysik J; Institute of Analytical Chemistry, Leipzig University, Leipzig, Germany., Zimmermann W; Institute of Analytical Chemistry, Leipzig University, Leipzig, Germany., Sträter N; Institute of Bioanalytical Chemistry, Centre for Biotechnology and Biomedicine, Leipzig University, Leipzig, Germany., Sonnendecker C; Institute of Analytical Chemistry, Leipzig University, Leipzig, Germany. christian.sonnendecker@uni-leipzig.de., Künze G; Institute for Drug Discovery, Leipzig University, Leipzig, Germany. georg.kuenze@uni-leipzig.de.; Interdisciplinary Center for Bioinformatics, Leipzig University, Leipzig, Germany. georg.kuenze@uni-leipzig.de.; Center for Scalable Data Analytics and Artificial Intelligence, Leipzig University, Leipzig, Germany. georg.kuenze@uni-leipzig.de.
Source: Nature communications [Nat Commun] 2026 May 15; Vol. 17 (1). Date of Electronic Publication: 2026 May 15.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Computational engineering of the polyester hydrolase PHL7 for efficient poly(ethylene terephthalate) degradation in biocatalytic recycling processes.
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