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VEGFR2 is required for VEGF-C-VEGFR3-PI3Kα-mediated sprouting lymphangiogenesis.

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Title: VEGFR2 is required for VEGF-C-VEGFR3-PI3Kα-mediated sprouting lymphangiogenesis.
Authors: Schoofs H; Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden.; Division of Molecular Pathology, Oncode Institute, The Netherlands Cancer Institute, Amsterdam, the Netherlands., Zhang Y; Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden.; Wihuri Research Institute, Helsinki, Finland.; Faculty of Medicine, University of Helsinki, Helsinki, Finland., Ortsäter H; Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden., Lytvyn M; Molecular Genetics of Angiogenesis Group, Centro Nacional de Investigaciones Cardiovasculares (CNIC), Melchor Fernández Almagro, Madrid, Spain., Benedito R; Molecular Genetics of Angiogenesis Group, Centro Nacional de Investigaciones Cardiovasculares (CNIC), Melchor Fernández Almagro, Madrid, Spain.; Max Planck Institute for Molecular Biomedicine, Department of Functional Genetics, Münster, Germany., Mäkinen T; Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden. taija.makinen@helsinki.fi.; Wihuri Research Institute, Helsinki, Finland. taija.makinen@helsinki.fi.; Faculty of Medicine, University of Helsinki, Helsinki, Finland. taija.makinen@helsinki.fi.
Source: Nature communications [Nat Commun] 2026 May 15; Vol. 17 (1). Date of Electronic Publication: 2026 May 15.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: VEGFR2 is required for VEGF-C-VEGFR3-PI3Kα-mediated sprouting lymphangiogenesis.
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  Data: <searchLink fieldCode="AU" term="%22Schoofs+H%22">Schoofs H</searchLink>; Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden.; Division of Molecular Pathology, Oncode Institute, The Netherlands Cancer Institute, Amsterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Zhang+Y%22">Zhang Y</searchLink>; Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden.; Wihuri Research Institute, Helsinki, Finland.; Faculty of Medicine, University of Helsinki, Helsinki, Finland.<br /><searchLink fieldCode="AU" term="%22Ortsäter+H%22">Ortsäter H</searchLink>; Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden.<br /><searchLink fieldCode="AU" term="%22Lytvyn+M%22">Lytvyn M</searchLink>; Molecular Genetics of Angiogenesis Group, Centro Nacional de Investigaciones Cardiovasculares (CNIC), Melchor Fernández Almagro, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Benedito+R%22">Benedito R</searchLink>; Molecular Genetics of Angiogenesis Group, Centro Nacional de Investigaciones Cardiovasculares (CNIC), Melchor Fernández Almagro, Madrid, Spain.; Max Planck Institute for Molecular Biomedicine, Department of Functional Genetics, Münster, Germany.<br /><searchLink fieldCode="AU" term="%22Mäkinen+T%22">Mäkinen T</searchLink>; Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden. taija.makinen@helsinki.fi.; Wihuri Research Institute, Helsinki, Finland. taija.makinen@helsinki.fi.; Faculty of Medicine, University of Helsinki, Helsinki, Finland. taija.makinen@helsinki.fi.
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