α-Synuclein aggregates induce mitochondrial damage and trigger innate immunity to drive neuron-microglia communication.
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| Title: | α-Synuclein aggregates induce mitochondrial damage and trigger innate immunity to drive neuron-microglia communication. |
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| Authors: | Chakraborty R; Institut Pasteur, Université Paris Cité, CNRS UMR 3691, Membrane Traffic and Pathogenesis, Paris, France.; Université Paris-Saclay, Gif-sur-Yvette, France., Maya S; Institut Pasteur, Université Paris Cité, CNRS UMR 3691, Membrane Traffic and Pathogenesis, Paris, France., Testa V; Department of Pathology and Experimental Therapeutics, Bellvitge University Hospital-IDIBELL, Barcelona, Spain.; Institute of Biomedicine of the University of Barcelona (IBUB), Barcelona, Spain., Montero-Muñoz J; Department of Pathology and Experimental Therapeutics, Bellvitge University Hospital-IDIBELL, Barcelona, Spain.; Institute of Biomedicine of the University of Barcelona (IBUB), Barcelona, Spain., Nonaka T; Dementia Research Project, Tokyo Metropolitan Institute of Medical Science, Tokyo, Japan., Hasegawa M; Dementia Research Project, Tokyo Metropolitan Institute of Medical Science, Tokyo, Japan., Consiglio A; Department of Pathology and Experimental Therapeutics, Bellvitge University Hospital-IDIBELL, Barcelona, Spain.; Institute of Biomedicine of the University of Barcelona (IBUB), Barcelona, Spain., Zurzolo C; Institut Pasteur, Université Paris Cité, CNRS UMR 3691, Membrane Traffic and Pathogenesis, Paris, France. chiara.zurzolo@pasteur.fr. |
| Source: | Nature communications [Nat Commun] 2026 May 15; Vol. 17 (1). Date of Electronic Publication: 2026 May 15. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 42140967 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: α-Synuclein aggregates induce mitochondrial damage and trigger innate immunity to drive neuron-microglia communication. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Chakraborty+R%22">Chakraborty R</searchLink>; Institut Pasteur, Université Paris Cité, CNRS UMR 3691, Membrane Traffic and Pathogenesis, Paris, France.; Université Paris-Saclay, Gif-sur-Yvette, France.<br /><searchLink fieldCode="AU" term="%22Maya+S%22">Maya S</searchLink>; Institut Pasteur, Université Paris Cité, CNRS UMR 3691, Membrane Traffic and Pathogenesis, Paris, France.<br /><searchLink fieldCode="AU" term="%22Testa+V%22">Testa V</searchLink>; Department of Pathology and Experimental Therapeutics, Bellvitge University Hospital-IDIBELL, Barcelona, Spain.; Institute of Biomedicine of the University of Barcelona (IBUB), Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Montero-Muñoz+J%22">Montero-Muñoz J</searchLink>; Department of Pathology and Experimental Therapeutics, Bellvitge University Hospital-IDIBELL, Barcelona, Spain.; Institute of Biomedicine of the University of Barcelona (IBUB), Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Nonaka+T%22">Nonaka T</searchLink>; Dementia Research Project, Tokyo Metropolitan Institute of Medical Science, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Hasegawa+M%22">Hasegawa M</searchLink>; Dementia Research Project, Tokyo Metropolitan Institute of Medical Science, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Consiglio+A%22">Consiglio A</searchLink>; Department of Pathology and Experimental Therapeutics, Bellvitge University Hospital-IDIBELL, Barcelona, Spain.; Institute of Biomedicine of the University of Barcelona (IBUB), Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Zurzolo+C%22">Zurzolo C</searchLink>; Institut Pasteur, Université Paris Cité, CNRS UMR 3691, Membrane Traffic and Pathogenesis, Paris, France. chiara.zurzolo@pasteur.fr. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101528555%22">Nature communications</searchLink> [Nat Commun] 2026 May 15; Vol. 17 (1). <i>Date of Electronic Publication: </i>2026 May 15. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Pub%2E+Group%22">Nature Pub. Group </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101528555 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2041-1723 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220411723%22">20411723 </searchLink><i>NLM ISO Abbreviation: </i>Nat Commun <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=42140967 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1038/s41467-026-73136-7 Languages: – Code: eng Text: English Titles: – TitleFull: α-Synuclein aggregates induce mitochondrial damage and trigger innate immunity to drive neuron-microglia communication. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Chakraborty R – PersonEntity: Name: NameFull: Maya S – PersonEntity: Name: NameFull: Testa V – PersonEntity: Name: NameFull: Montero-Muñoz J – PersonEntity: Name: NameFull: Nonaka T – PersonEntity: Name: NameFull: Hasegawa M – PersonEntity: Name: NameFull: Consiglio A – PersonEntity: Name: NameFull: Zurzolo C IsPartOfRelationships: – BibEntity: Dates: – D: 15 M: 05 Text: 2026 May 15 Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 2041-1723 Numbering: – Type: volume Value: 17 – Type: issue Value: 1 Titles: – TitleFull: Nature communications Type: main |
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