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Mechanisms and functions of large extracellular vesicle biogenesis.

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Title: Mechanisms and functions of large extracellular vesicle biogenesis.
Authors: Rutter SF; Department of Biochemistry and Chemistry, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, Victoria, Australia.; Research Centre for Extracellular Vesicles, La Trobe University, Melbourne, Victoria, Australia., Santavanond JP; Department of Biochemistry and Chemistry, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, Victoria, Australia.; Research Centre for Extracellular Vesicles, La Trobe University, Melbourne, Victoria, Australia., Hsu AY, Silva TF; Department of Urology, Division of Cancer Biology and Therapeutics, Cedars-Sinai Medical Center, Los Angeles, CA, USA., Di Vizio D; Department of Urology, Division of Cancer Biology and Therapeutics, Cedars-Sinai Medical Center, Los Angeles, CA, USA. dolores.divizio@uniroma1.it.; Department of Radiological, Oncological, and Pathological Sciences, Sapienza University, Rome, Italy. dolores.divizio@uniroma1.it., Poon IKH; Department of Biochemistry and Chemistry, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, Victoria, Australia. i.poon@latrobe.edu.au.; Research Centre for Extracellular Vesicles, La Trobe University, Melbourne, Victoria, Australia. i.poon@latrobe.edu.au.
Source: Nature cell biology [Nat Cell Biol] 2026 Jun; Vol. 28 (6), pp. 1113-1126. Date of Electronic Publication: 2026 May 15.
Publication Type: Journal Article; Review
Journal Info: Publisher: Macmillan Magazines Ltd Country of Publication: England NLM ID: 100890575 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4679 (Electronic) Linking ISSN: 14657392 NLM ISO Abbreviation: Nat Cell Biol Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Rutter+SF%22">Rutter SF</searchLink>; Department of Biochemistry and Chemistry, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, Victoria, Australia.; Research Centre for Extracellular Vesicles, La Trobe University, Melbourne, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Santavanond+JP%22">Santavanond JP</searchLink>; Department of Biochemistry and Chemistry, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, Victoria, Australia.; Research Centre for Extracellular Vesicles, La Trobe University, Melbourne, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Hsu+AY%22">Hsu AY</searchLink><br /><searchLink fieldCode="AU" term="%22Silva+TF%22">Silva TF</searchLink>; Department of Urology, Division of Cancer Biology and Therapeutics, Cedars-Sinai Medical Center, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Di+Vizio+D%22">Di Vizio D</searchLink>; Department of Urology, Division of Cancer Biology and Therapeutics, Cedars-Sinai Medical Center, Los Angeles, CA, USA. dolores.divizio@uniroma1.it.; Department of Radiological, Oncological, and Pathological Sciences, Sapienza University, Rome, Italy. dolores.divizio@uniroma1.it.<br /><searchLink fieldCode="AU" term="%22Poon+IKH%22">Poon IKH</searchLink>; Department of Biochemistry and Chemistry, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, Victoria, Australia. i.poon@latrobe.edu.au.; Research Centre for Extracellular Vesicles, La Trobe University, Melbourne, Victoria, Australia. i.poon@latrobe.edu.au.
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  Data: <searchLink fieldCode="JN" term="%22100890575%22">Nature cell biology</searchLink> [Nat Cell Biol] 2026 Jun; Vol. 28 (6), pp. 1113-1126. <i>Date of Electronic Publication: </i>2026 May 15.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Macmillan+Magazines+Ltd%22">Macmillan Magazines Ltd </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>100890575 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1476-4679 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2214657392%22">14657392 </searchLink><i>NLM ISO Abbreviation: </i>Nat Cell Biol <i>Subsets: </i>MEDLINE
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        Value: 10.1038/s41556-026-01940-w
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              Text: 2026 Jun
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