Population-scale genomic medicine with the Hong Kong Genome Project.
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| Title: | Population-scale genomic medicine with the Hong Kong Genome Project. |
|---|---|
| Authors: | Ying D; Hong Kong Genome Institute, Hong Kong SAR, China., Cheung CL; Department of Pharmacology and Pharmacy, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China.; Laboratory of Data Discovery for Health Limited (D24H), Hong Kong Science Parks, Hong Kong SAR, China.; Hinda and Arthur Marcus Institute for Aging Research, Hebrew SeniorLife, Boston, MA, USA., O CK; Department of Medicine and Therapeutics, Faculty of Medicine, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong SAR, China.; Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong SAR, China., Lam WKJ; Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong SAR, China.; Department of Chemical Pathology, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong SAR, China., Au Yeung SL; School of Public Health, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China., Lau CS; Department of Medicine, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China., Luk HM; Department of Clinical Genetics, Hong Kong Children's Hospital, Hong Kong SAR, China., Leung CKS; Department of Ophthalmology, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China.; Department of Ophthalmology, Queen Mary Hospital, Hong Kong SAR, China.; Hong Kong Eye Hospital, Hong Kong SAR, China.; Grantham Hospital, Hong Kong SAR, China., Tse DMS; Hong Kong Genome Institute, Hong Kong SAR, China., Liu JSC; Hong Kong Genome Institute, Hong Kong SAR, China., Hue SPY; Hong Kong Genome Institute, Hong Kong SAR, China., Kwok JSL; Hong Kong Genome Institute, Hong Kong SAR, China., Yeung DLH; Hong Kong Genome Institute, Hong Kong SAR, China., Preusch CB; Hong Kong Genome Institute, Hong Kong SAR, China., Ma W; Hong Kong Genome Institute, Hong Kong SAR, China., Tang W; Hong Kong Genome Institute, Hong Kong SAR, China., Tong AHY; Hong Kong Genome Institute, Hong Kong SAR, China., Au LWC; Department of Medicine and Therapeutics, Faculty of Medicine, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong SAR, China., Chan JC; Department of Medicine and Therapeutics, Faculty of Medicine, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong SAR, China.; Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong SAR, China.; Hong Kong Institute of Diabetes and Obesity, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong SAR, China., Chan YH; Department of Medicine, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China., Cheng SSW; Department of Clinical Genetics, Hong Kong Children's Hospital, Hong Kong SAR, China., Chong SC; Department of Paediatrics, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong SAR, China.; Department of Obstetrics and Gynaecology, The Chinese University of Hong Kong, Hong Kong SAR, China.; Joint Baylor-CUHK Center of Medical Genetics, The Chinese University of Hong Kong, Hong Kong SAR, China., Fung CW; Department of Paediatrics and Adolescent Medicine, Hong Kong Children's Hospital, Hong Kong SAR, China., Ho S; Department of Clinical Genetics, Hong Kong Children's Hospital, Hong Kong SAR, China., Krishnamoorthy S; Department of Pharmacology and Pharmacy, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China., Leung GM; Laboratory of Data Discovery for Health Limited (D24H), Hong Kong Science Parks, Hong Kong SAR, China.; School of Public Health, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China., Li PH; Department of Medicine, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China., Li Q; Department of Ophthalmology, Queen Mary Hospital, Hong Kong SAR, China.; Grantham Hospital, Hong Kong SAR, China., Loong HH; Department of Clinical Oncology, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong SAR, China.; State Key Laboratory of Translational Oncology, The Chinese University of Hong Kong, Hong Kong SAR, China., Lui RNS; Department of Medicine and Therapeutics, Faculty of Medicine, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong SAR, China.; Medical Data Analytics Centre, The Chinese University of Hong Kong, Hong Kong SAR, China.; Institute of Digestive Disease, The Chinese University of Hong Kong, Hong Kong SAR, China., Luo S; School of Public Health, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China.; Department of Family Medicine and Primary Care, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China., Ma BM; Department of Medicine, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China., Ma RCW; Department of Medicine and Therapeutics, Faculty of Medicine, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong SAR, China.; Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong SAR, China.; Hong Kong Institute of Diabetes and Obesity, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong SAR, China., Na R; Department of Surgery, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China., Tan KCB; Department of Medicine, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China., Wong SS; Department of Paediatrics and Adolescent Medicine, Hong Kong Children's Hospital, Hong Kong SAR, China., Lo SV; Hong Kong Genome Institute, Hong Kong SAR, China., Chu ATW; Hong Kong Genome Institute, Hong Kong SAR, China., Chung BHY; Hong Kong Genome Institute, Hong Kong SAR, China. bhychung@hku.hk.; Department of Paediatrics and Adolescent Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China. bhychung@hku.hk. |
| Corporate Authors: | Hong Kong Genome Project |
| Source: | Nature medicine [Nat Med] 2026 Jun; Vol. 32 (6), pp. 2277-2287. Date of Electronic Publication: 2026 May 15. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Publishing Company Country of Publication: United States NLM ID: 9502015 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-170X (Electronic) Linking ISSN: 10788956 NLM ISO Abbreviation: Nat Med Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 42141198 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Population-scale genomic medicine with the Hong Kong Genome Project. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Ying+D%22">Ying D</searchLink>; Hong Kong Genome Institute, Hong Kong SAR, China.<br /><searchLink fieldCode="AU" term="%22Cheung+CL%22">Cheung CL</searchLink>; Department of Pharmacology and Pharmacy, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China.; Laboratory of Data Discovery for Health Limited (D24H), Hong Kong Science Parks, Hong Kong SAR, China.; Hinda and Arthur Marcus Institute for Aging Research, Hebrew SeniorLife, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22O+CK%22">O CK</searchLink>; Department of Medicine and Therapeutics, Faculty of Medicine, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong SAR, China.; Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong SAR, China.<br /><searchLink fieldCode="AU" term="%22Lam+WKJ%22">Lam WKJ</searchLink>; Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong SAR, China.; Department of Chemical Pathology, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong SAR, China.<br /><searchLink fieldCode="AU" term="%22Au+Yeung+SL%22">Au Yeung SL</searchLink>; School of Public Health, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China.<br /><searchLink fieldCode="AU" term="%22Lau+CS%22">Lau CS</searchLink>; Department of Medicine, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China.<br /><searchLink fieldCode="AU" term="%22Luk+HM%22">Luk HM</searchLink>; Department of Clinical Genetics, Hong Kong Children's Hospital, Hong Kong SAR, China.<br /><searchLink fieldCode="AU" term="%22Leung+CKS%22">Leung CKS</searchLink>; Department of Ophthalmology, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China.; Department of Ophthalmology, Queen Mary Hospital, Hong Kong SAR, China.; Hong Kong Eye Hospital, Hong Kong SAR, China.; Grantham Hospital, Hong Kong SAR, China.<br /><searchLink fieldCode="AU" term="%22Tse+DMS%22">Tse DMS</searchLink>; Hong Kong Genome Institute, Hong Kong SAR, China.<br /><searchLink fieldCode="AU" term="%22Liu+JSC%22">Liu JSC</searchLink>; Hong Kong Genome Institute, Hong Kong SAR, China.<br /><searchLink fieldCode="AU" term="%22Hue+SPY%22">Hue SPY</searchLink>; Hong Kong Genome Institute, Hong Kong SAR, China.<br /><searchLink fieldCode="AU" term="%22Kwok+JSL%22">Kwok JSL</searchLink>; Hong Kong Genome Institute, Hong Kong SAR, China.<br /><searchLink fieldCode="AU" term="%22Yeung+DLH%22">Yeung DLH</searchLink>; Hong Kong Genome Institute, Hong Kong SAR, China.<br /><searchLink fieldCode="AU" term="%22Preusch+CB%22">Preusch CB</searchLink>; Hong Kong Genome Institute, Hong Kong SAR, China.<br /><searchLink fieldCode="AU" term="%22Ma+W%22">Ma W</searchLink>; Hong Kong Genome Institute, Hong Kong SAR, China.<br /><searchLink fieldCode="AU" term="%22Tang+W%22">Tang W</searchLink>; Hong Kong Genome Institute, Hong Kong SAR, China.<br /><searchLink fieldCode="AU" term="%22Tong+AHY%22">Tong AHY</searchLink>; Hong Kong Genome Institute, Hong Kong SAR, China.<br /><searchLink fieldCode="AU" term="%22Au+LWC%22">Au LWC</searchLink>; Department of Medicine and Therapeutics, Faculty of Medicine, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong SAR, China.<br /><searchLink fieldCode="AU" term="%22Chan+JC%22">Chan JC</searchLink>; Department of Medicine and Therapeutics, Faculty of Medicine, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong SAR, China.; Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong SAR, China.; Hong Kong Institute of Diabetes and Obesity, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong SAR, China.<br /><searchLink fieldCode="AU" term="%22Chan+YH%22">Chan YH</searchLink>; Department of Medicine, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China.<br /><searchLink fieldCode="AU" term="%22Cheng+SSW%22">Cheng SSW</searchLink>; Department of Clinical Genetics, Hong Kong Children's Hospital, Hong Kong SAR, China.<br /><searchLink fieldCode="AU" term="%22Chong+SC%22">Chong SC</searchLink>; Department of Paediatrics, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong SAR, China.; Department of Obstetrics and Gynaecology, The Chinese University of Hong Kong, Hong Kong SAR, China.; Joint Baylor-CUHK Center of Medical Genetics, The Chinese University of Hong Kong, Hong Kong SAR, China.<br /><searchLink fieldCode="AU" term="%22Fung+CW%22">Fung CW</searchLink>; Department of Paediatrics and Adolescent Medicine, Hong Kong Children's Hospital, Hong Kong SAR, China.<br /><searchLink fieldCode="AU" term="%22Ho+S%22">Ho S</searchLink>; Department of Clinical Genetics, Hong Kong Children's Hospital, Hong Kong SAR, China.<br /><searchLink fieldCode="AU" term="%22Krishnamoorthy+S%22">Krishnamoorthy S</searchLink>; Department of Pharmacology and Pharmacy, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China.<br /><searchLink fieldCode="AU" term="%22Leung+GM%22">Leung GM</searchLink>; Laboratory of Data Discovery for Health Limited (D24H), Hong Kong Science Parks, Hong Kong SAR, China.; School of Public Health, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China.<br /><searchLink fieldCode="AU" term="%22Li+PH%22">Li PH</searchLink>; Department of Medicine, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China.<br /><searchLink fieldCode="AU" term="%22Li+Q%22">Li Q</searchLink>; Department of Ophthalmology, Queen Mary Hospital, Hong Kong SAR, China.; Grantham Hospital, Hong Kong SAR, China.<br /><searchLink fieldCode="AU" term="%22Loong+HH%22">Loong HH</searchLink>; Department of Clinical Oncology, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong SAR, China.; State Key Laboratory of Translational Oncology, The Chinese University of Hong Kong, Hong Kong SAR, China.<br /><searchLink fieldCode="AU" term="%22Lui+RNS%22">Lui RNS</searchLink>; Department of Medicine and Therapeutics, Faculty of Medicine, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong SAR, China.; Medical Data Analytics Centre, The Chinese University of Hong Kong, Hong Kong SAR, China.; Institute of Digestive Disease, The Chinese University of Hong Kong, Hong Kong SAR, China.<br /><searchLink fieldCode="AU" term="%22Luo+S%22">Luo S</searchLink>; School of Public Health, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China.; Department of Family Medicine and Primary Care, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China.<br /><searchLink fieldCode="AU" term="%22Ma+BM%22">Ma BM</searchLink>; Department of Medicine, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China.<br /><searchLink fieldCode="AU" term="%22Ma+RCW%22">Ma RCW</searchLink>; Department of Medicine and Therapeutics, Faculty of Medicine, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong SAR, China.; Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong SAR, China.; Hong Kong Institute of Diabetes and Obesity, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong SAR, China.<br /><searchLink fieldCode="AU" term="%22Na+R%22">Na R</searchLink>; Department of Surgery, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China.<br /><searchLink fieldCode="AU" term="%22Tan+KCB%22">Tan KCB</searchLink>; Department of Medicine, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China.<br /><searchLink fieldCode="AU" term="%22Wong+SS%22">Wong SS</searchLink>; Department of Paediatrics and Adolescent Medicine, Hong Kong Children's Hospital, Hong Kong SAR, China.<br /><searchLink fieldCode="AU" term="%22Lo+SV%22">Lo SV</searchLink>; Hong Kong Genome Institute, Hong Kong SAR, China.<br /><searchLink fieldCode="AU" term="%22Chu+ATW%22">Chu ATW</searchLink>; Hong Kong Genome Institute, Hong Kong SAR, China.<br /><searchLink fieldCode="AU" term="%22Chung+BHY%22">Chung BHY</searchLink>; Hong Kong Genome Institute, Hong Kong SAR, China. bhychung@hku.hk.; Department of Paediatrics and Adolescent Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China. bhychung@hku.hk. – Name: AuthorCorporate Label: Corporate Authors Group: Au Data: <searchLink fieldCode="CA" term="%22Hong+Kong+Genome+Project%22">Hong Kong Genome Project</searchLink> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%229502015%22">Nature medicine</searchLink> [Nat Med] 2026 Jun; Vol. 32 (6), pp. 2277-2287. <i>Date of Electronic Publication: </i>2026 May 15. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Publishing+Company%22">Nature Publishing Company </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>9502015 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1546-170X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2210788956%22">10788956 </searchLink><i>NLM ISO Abbreviation: </i>Nat Med <i>Subsets: </i>MEDLINE |
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