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Twenty-year results of the randomized European Organization for Research and Treatment of Cancer trial 22922/10925 evaluating internal mammary chain and medial supraclavicular lymph node irradiation in stage I-III breast cancer.

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Title: Twenty-year results of the randomized European Organization for Research and Treatment of Cancer trial 22922/10925 evaluating internal mammary chain and medial supraclavicular lymph node irradiation in stage I-III breast cancer.
Authors: Kaidar-Person O; Breast Radiation Unit, Sheba Medical Center, Ramat Gan, Israel.; Gray Faculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv, Israel., Weltens CG; Department of Radiation Oncology, University Hospitals Leuven, Leuven, Belgium.; Laboratory of Experimental Radiation Oncology, Katholieke Universiteit te Leuven, Leuven, Belgium., Fortpied C; European Organization for Research and Treatment of Cancer, Brussels, Belgium., Scheijmans LJEE; Department of Radiation Oncology, Institute Verbeeten, Tilburg, Netherlands., Kirkove CY; Department of Radiation Oncology, University Hospital Saint Luc, Université Catholique de Louvain, Brussels, Belgium., Budach V; Department of Radiation Oncology, Comprehensive Cancer Center, Charite-University Medicine Berlin, Corporate Member of Free University of Berlin and Humboldt University of Berlin, BE, Berlin, Germany.; Radiation Oncology Vosspalais, BE, Berlin, Germany., Peignaux-Casasnovas K; Department of Radiation Oncology, Centre Georges François Leclerc, Dijon, France., Valli M; Department of Radiation Oncology, Sant Anna Hospital, Como, Italy.; Department of Radiation Oncology, Ospedale Valduce, Como, Italy., Peters M; Department of Radiation Oncology, Radiotherapiegroep, Deventer/Arnhem, Netherlands., van der Leij F; Department of Radiation Oncology, University Medical Centre Utrecht, Utrecht, Netherlands., Rivera S; Department of Radiation Oncology, Gustave Roussy Cancer Centre, Villejuif, France., Weidner N; Department of Radiation Oncology, University Hospital, Tübingen, Germany., van den Bongard DHJG; Department of Radiation Oncology, Cancer Center Amsterdam, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, Netherlands., Linsenmeier C; Department of Radiation Oncology, University Hospital Zürich, University of Zürich, Zürich, Switzerland., Abdah-Bortnyak R; Department of Radiation Oncology, The Joseph Fishman Oncology Center, Rambam Health Care Campus, Haifa, Israel., Hosni S; Nottingham University Hospitals National Health Service Trust, Nottingham, UK., Koiter E; Department of Radiation Oncology, Medisch Spectrum Twente, Enschede, Netherlands., Engelen AM; Department of Radiation Oncology, Institute Verbeeten, Tilburg, Netherlands., Baten A; Department of Radiation Oncology, University Hospitals Leuven, Leuven, Belgium.; Laboratory of Experimental Radiation Oncology, Katholieke Universiteit te Leuven, Leuven, Belgium., Champezou L; European Organization for Research and Treatment of Cancer, Brussels, Belgium., Fourquet A; Department of Radiation Oncology, Institut Curie, Paris, France., Bartelink HGMM; Department of Radiation Oncology, Netherlands Cancer Institute, Amsterdam, Netherlands., Struikmans H; Department of Radiation Oncology, Haaglanden Medical Center the Hague, Leidschendam, Netherlands., Poortmans PMP; Department of Radiation Oncology, Iridium Netwerk, Wilrijk-Antwerp, Belgium.; Faculty of Medicine and Health Sciences, University of Antwerp, Wilrijk-Antwerp, Belgium.
Corporate Authors: European Organization for Research and Treatment of Cancer Radiation Oncology and Breast Cancer Groups
Source: CA: a cancer journal for clinicians [CA Cancer J Clin] 2026 May-Jun; Vol. 76 (3), pp. e70082.
Publication Type: Journal Article; Randomized Controlled Trial
Journal Info: Publisher: Wiley Country of Publication: United States NLM ID: 0370647 Publication Model: Print Cited Medium: Internet ISSN: 1542-4863 (Electronic) Linking ISSN: 00079235 NLM ISO Abbreviation: CA Cancer J Clin Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Twenty-year results of the randomized European Organization for Research and Treatment of Cancer trial 22922/10925 evaluating internal mammary chain and medial supraclavicular lymph node irradiation in stage I-III breast cancer.
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  Data: <searchLink fieldCode="AU" term="%22Kaidar-Person+O%22">Kaidar-Person O</searchLink>; Breast Radiation Unit, Sheba Medical Center, Ramat Gan, Israel.; Gray Faculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv, Israel.<br /><searchLink fieldCode="AU" term="%22Weltens+CG%22">Weltens CG</searchLink>; Department of Radiation Oncology, University Hospitals Leuven, Leuven, Belgium.; Laboratory of Experimental Radiation Oncology, Katholieke Universiteit te Leuven, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Fortpied+C%22">Fortpied C</searchLink>; European Organization for Research and Treatment of Cancer, Brussels, Belgium.<br /><searchLink fieldCode="AU" term="%22Scheijmans+LJEE%22">Scheijmans LJEE</searchLink>; Department of Radiation Oncology, Institute Verbeeten, Tilburg, Netherlands.<br /><searchLink fieldCode="AU" term="%22Kirkove+CY%22">Kirkove CY</searchLink>; Department of Radiation Oncology, University Hospital Saint Luc, Université Catholique de Louvain, Brussels, Belgium.<br /><searchLink fieldCode="AU" term="%22Budach+V%22">Budach V</searchLink>; Department of Radiation Oncology, Comprehensive Cancer Center, Charite-University Medicine Berlin, Corporate Member of Free University of Berlin and Humboldt University of Berlin, BE, Berlin, Germany.; Radiation Oncology Vosspalais, BE, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Peignaux-Casasnovas+K%22">Peignaux-Casasnovas K</searchLink>; Department of Radiation Oncology, Centre Georges François Leclerc, Dijon, France.<br /><searchLink fieldCode="AU" term="%22Valli+M%22">Valli M</searchLink>; Department of Radiation Oncology, Sant Anna Hospital, Como, Italy.; Department of Radiation Oncology, Ospedale Valduce, Como, Italy.<br /><searchLink fieldCode="AU" term="%22Peters+M%22">Peters M</searchLink>; Department of Radiation Oncology, Radiotherapiegroep, Deventer/Arnhem, Netherlands.<br /><searchLink fieldCode="AU" term="%22van+der+Leij+F%22">van der Leij F</searchLink>; Department of Radiation Oncology, University Medical Centre Utrecht, Utrecht, Netherlands.<br /><searchLink fieldCode="AU" term="%22Rivera+S%22">Rivera S</searchLink>; Department of Radiation Oncology, Gustave Roussy Cancer Centre, Villejuif, France.<br /><searchLink fieldCode="AU" term="%22Weidner+N%22">Weidner N</searchLink>; Department of Radiation Oncology, University Hospital, Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22van+den+Bongard+DHJG%22">van den Bongard DHJG</searchLink>; Department of Radiation Oncology, Cancer Center Amsterdam, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, Netherlands.<br /><searchLink fieldCode="AU" term="%22Linsenmeier+C%22">Linsenmeier C</searchLink>; Department of Radiation Oncology, University Hospital Zürich, University of Zürich, Zürich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Abdah-Bortnyak+R%22">Abdah-Bortnyak R</searchLink>; Department of Radiation Oncology, The Joseph Fishman Oncology Center, Rambam Health Care Campus, Haifa, Israel.<br /><searchLink fieldCode="AU" term="%22Hosni+S%22">Hosni S</searchLink>; Nottingham University Hospitals National Health Service Trust, Nottingham, UK.<br /><searchLink fieldCode="AU" term="%22Koiter+E%22">Koiter E</searchLink>; Department of Radiation Oncology, Medisch Spectrum Twente, Enschede, Netherlands.<br /><searchLink fieldCode="AU" term="%22Engelen+AM%22">Engelen AM</searchLink>; Department of Radiation Oncology, Institute Verbeeten, Tilburg, Netherlands.<br /><searchLink fieldCode="AU" term="%22Baten+A%22">Baten A</searchLink>; Department of Radiation Oncology, University Hospitals Leuven, Leuven, Belgium.; Laboratory of Experimental Radiation Oncology, Katholieke Universiteit te Leuven, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Champezou+L%22">Champezou L</searchLink>; European Organization for Research and Treatment of Cancer, Brussels, Belgium.<br /><searchLink fieldCode="AU" term="%22Fourquet+A%22">Fourquet A</searchLink>; Department of Radiation Oncology, Institut Curie, Paris, France.<br /><searchLink fieldCode="AU" term="%22Bartelink+HGMM%22">Bartelink HGMM</searchLink>; Department of Radiation Oncology, Netherlands Cancer Institute, Amsterdam, Netherlands.<br /><searchLink fieldCode="AU" term="%22Struikmans+H%22">Struikmans H</searchLink>; Department of Radiation Oncology, Haaglanden Medical Center the Hague, Leidschendam, Netherlands.<br /><searchLink fieldCode="AU" term="%22Poortmans+PMP%22">Poortmans PMP</searchLink>; Department of Radiation Oncology, Iridium Netwerk, Wilrijk-Antwerp, Belgium.; Faculty of Medicine and Health Sciences, University of Antwerp, Wilrijk-Antwerp, Belgium.
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