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Developing a durable, memory-driven, CspZ-targeting Lyme disease vaccine by rationale adjuvant selection.

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Title: Developing a durable, memory-driven, CspZ-targeting Lyme disease vaccine by rationale adjuvant selection.
Authors: McCarty M; Department of Infectious Disease and Global Health, Cummings School of Veterinary Medicine, Tufts University, North Grafton, MA, USA., Hernández SA; Department of Infectious Disease and Global Health, Cummings School of Veterinary Medicine, Tufts University, North Grafton, MA, USA.; Department of Molecular Biology and Microbiology, School of Medicine, Tufts University, Boston, MA, USA., Malfetano J; Division of Infectious Diseases, Wadsworth Center, NYSDOH, Albany, NY, USA., Leão AC; Department of Pediatrics (Tropical Medicine), National School of Tropical Medicine, Baylor College of Medicine, Houston, TX, USA.; Texas Children's Hospital Center for Vaccine Development, Houston, TX, USA., Villar MJ; Department of Pediatrics (Tropical Medicine), National School of Tropical Medicine, Baylor College of Medicine, Houston, TX, USA.; Texas Children's Hospital Center for Vaccine Development, Houston, TX, USA., Yang X; Department of Veterinary Medicine, Virginia-Maryland Regional College of Veterinary Medicine, University of Maryland, College Park, MD, USA., Chen YL; Department of Pediatrics (Tropical Medicine), National School of Tropical Medicine, Baylor College of Medicine, Houston, TX, USA.; Texas Children's Hospital Center for Vaccine Development, Houston, TX, USA., Lee J; Department of Pediatrics (Tropical Medicine), National School of Tropical Medicine, Baylor College of Medicine, Houston, TX, USA.; Texas Children's Hospital Center for Vaccine Development, Houston, TX, USA., Liu Z; Department of Pediatrics (Tropical Medicine), National School of Tropical Medicine, Baylor College of Medicine, Houston, TX, USA.; Texas Children's Hospital Center for Vaccine Development, Houston, TX, USA., Strych U; Department of Pediatrics (Tropical Medicine), National School of Tropical Medicine, Baylor College of Medicine, Houston, TX, USA.; Texas Children's Hospital Center for Vaccine Development, Houston, TX, USA., Bottazzi ME; Department of Pediatrics (Tropical Medicine), National School of Tropical Medicine, Baylor College of Medicine, Houston, TX, USA.; Texas Children's Hospital Center for Vaccine Development, Houston, TX, USA.; Department of Biology, Baylor University, Waco, TX, USA., Pal U; Department of Veterinary Medicine, Virginia-Maryland Regional College of Veterinary Medicine, University of Maryland, College Park, MD, USA., Strle K; Department of Molecular Biology and Microbiology, School of Medicine, Tufts University, Boston, MA, USA., Chen WH; Department of Pediatrics (Tropical Medicine), National School of Tropical Medicine, Baylor College of Medicine, Houston, TX, USA. Wen-Hsiang.Chen@bcm.edu.; Texas Children's Hospital Center for Vaccine Development, Houston, TX, USA. Wen-Hsiang.Chen@bcm.edu., Lin YP; Department of Infectious Disease and Global Health, Cummings School of Veterinary Medicine, Tufts University, North Grafton, MA, USA. Yi-Pin.Lin@tufts.edu.; Division of Infectious Diseases, Wadsworth Center, NYSDOH, Albany, NY, USA. Yi-Pin.Lin@tufts.edu.
Source: NPJ vaccines [NPJ Vaccines] 2026 May 16. Date of Electronic Publication: 2026 May 16.
Publication Type: Journal Article
Journal Info: Publisher: Springer Nature in partnership with the Sealy Center for Vaccine Development Country of Publication: England NLM ID: 101699863 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2059-0105 (Electronic) Linking ISSN: 20590105 NLM ISO Abbreviation: NPJ Vaccines
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22McCarty+M%22">McCarty M</searchLink>; Department of Infectious Disease and Global Health, Cummings School of Veterinary Medicine, Tufts University, North Grafton, MA, USA.<br /><searchLink fieldCode="AU" term="%22Hernández+SA%22">Hernández SA</searchLink>; Department of Infectious Disease and Global Health, Cummings School of Veterinary Medicine, Tufts University, North Grafton, MA, USA.; Department of Molecular Biology and Microbiology, School of Medicine, Tufts University, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Malfetano+J%22">Malfetano J</searchLink>; Division of Infectious Diseases, Wadsworth Center, NYSDOH, Albany, NY, USA.<br /><searchLink fieldCode="AU" term="%22Leão+AC%22">Leão AC</searchLink>; Department of Pediatrics (Tropical Medicine), National School of Tropical Medicine, Baylor College of Medicine, Houston, TX, USA.; Texas Children's Hospital Center for Vaccine Development, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Villar+MJ%22">Villar MJ</searchLink>; Department of Pediatrics (Tropical Medicine), National School of Tropical Medicine, Baylor College of Medicine, Houston, TX, USA.; Texas Children's Hospital Center for Vaccine Development, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Yang+X%22">Yang X</searchLink>; Department of Veterinary Medicine, Virginia-Maryland Regional College of Veterinary Medicine, University of Maryland, College Park, MD, USA.<br /><searchLink fieldCode="AU" term="%22Chen+YL%22">Chen YL</searchLink>; Department of Pediatrics (Tropical Medicine), National School of Tropical Medicine, Baylor College of Medicine, Houston, TX, USA.; Texas Children's Hospital Center for Vaccine Development, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Lee+J%22">Lee J</searchLink>; Department of Pediatrics (Tropical Medicine), National School of Tropical Medicine, Baylor College of Medicine, Houston, TX, USA.; Texas Children's Hospital Center for Vaccine Development, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Liu+Z%22">Liu Z</searchLink>; Department of Pediatrics (Tropical Medicine), National School of Tropical Medicine, Baylor College of Medicine, Houston, TX, USA.; Texas Children's Hospital Center for Vaccine Development, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Strych+U%22">Strych U</searchLink>; Department of Pediatrics (Tropical Medicine), National School of Tropical Medicine, Baylor College of Medicine, Houston, TX, USA.; Texas Children's Hospital Center for Vaccine Development, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Bottazzi+ME%22">Bottazzi ME</searchLink>; Department of Pediatrics (Tropical Medicine), National School of Tropical Medicine, Baylor College of Medicine, Houston, TX, USA.; Texas Children's Hospital Center for Vaccine Development, Houston, TX, USA.; Department of Biology, Baylor University, Waco, TX, USA.<br /><searchLink fieldCode="AU" term="%22Pal+U%22">Pal U</searchLink>; Department of Veterinary Medicine, Virginia-Maryland Regional College of Veterinary Medicine, University of Maryland, College Park, MD, USA.<br /><searchLink fieldCode="AU" term="%22Strle+K%22">Strle K</searchLink>; Department of Molecular Biology and Microbiology, School of Medicine, Tufts University, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Chen+WH%22">Chen WH</searchLink>; Department of Pediatrics (Tropical Medicine), National School of Tropical Medicine, Baylor College of Medicine, Houston, TX, USA. Wen-Hsiang.Chen@bcm.edu.; Texas Children's Hospital Center for Vaccine Development, Houston, TX, USA. Wen-Hsiang.Chen@bcm.edu.<br /><searchLink fieldCode="AU" term="%22Lin+YP%22">Lin YP</searchLink>; Department of Infectious Disease and Global Health, Cummings School of Veterinary Medicine, Tufts University, North Grafton, MA, USA. Yi-Pin.Lin@tufts.edu.; Division of Infectious Diseases, Wadsworth Center, NYSDOH, Albany, NY, USA. Yi-Pin.Lin@tufts.edu.
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