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EDL6D, a bioactive peptide phenocopying SHBG-associated metabolic effects: a new preclinical lead compound for treating the metabolic dysfunction-associated fatty liver disease.

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Title: EDL6D, a bioactive peptide phenocopying SHBG-associated metabolic effects: a new preclinical lead compound for treating the metabolic dysfunction-associated fatty liver disease.
Authors: Alvarez-Guaita A; Diabetes and Metabolism Research Unit, Vall d' Hebron Institut de Recerca (VHIR), Universitat Autònoma de Barcelona and CIBERDEM (ISCIII), Pg Vall d'Hebron 119-129, Barcelona, 08035, Spain.; Endolipid Therapeutics S.L, Vall Hebron Institut de Recerca (VHIR), Barcelona, Spain., Cabrera-Serra J; Diabetes and Metabolism Research Unit, Vall d' Hebron Institut de Recerca (VHIR), Universitat Autònoma de Barcelona and CIBERDEM (ISCIII), Pg Vall d'Hebron 119-129, Barcelona, 08035, Spain., Perez-Gonzalez B; Diabetes and Metabolism Research Unit, Vall d' Hebron Institut de Recerca (VHIR), Universitat Autònoma de Barcelona and CIBERDEM (ISCIII), Pg Vall d'Hebron 119-129, Barcelona, 08035, Spain.; Endolipid Therapeutics S.L, Vall Hebron Institut de Recerca (VHIR), Barcelona, Spain., Salcedo-Allende MT; Human Pathology Department, Vall d'Hebron University Hospital, Barcelona, Spain., Fuertes-Rioja L; Diabetes and Metabolism Research Unit, Vall d' Hebron Institut de Recerca (VHIR), Universitat Autònoma de Barcelona and CIBERDEM (ISCIII), Pg Vall d'Hebron 119-129, Barcelona, 08035, Spain., Ramos-Perez L; Diabetes and Metabolism Research Unit, Vall d' Hebron Institut de Recerca (VHIR), Universitat Autònoma de Barcelona and CIBERDEM (ISCIII), Pg Vall d'Hebron 119-129, Barcelona, 08035, Spain., Hernandez C; Diabetes and Metabolism Research Unit, Vall d' Hebron Institut de Recerca (VHIR), Universitat Autònoma de Barcelona and CIBERDEM (ISCIII), Pg Vall d'Hebron 119-129, Barcelona, 08035, Spain., Simó R; Diabetes and Metabolism Research Unit, Vall d' Hebron Institut de Recerca (VHIR), Universitat Autònoma de Barcelona and CIBERDEM (ISCIII), Pg Vall d'Hebron 119-129, Barcelona, 08035, Spain.; Endolipid Therapeutics S.L, Vall Hebron Institut de Recerca (VHIR), Barcelona, Spain., Selva DM; Diabetes and Metabolism Research Unit, Vall d' Hebron Institut de Recerca (VHIR), Universitat Autònoma de Barcelona and CIBERDEM (ISCIII), Pg Vall d'Hebron 119-129, Barcelona, 08035, Spain. david.martinez.selva@vhir.org.; Endolipid Therapeutics S.L, Vall Hebron Institut de Recerca (VHIR), Barcelona, Spain. david.martinez.selva@vhir.org.
Source: Journal of translational medicine [J Transl Med] 2026 May 16; Vol. 24 (1). Date of Electronic Publication: 2026 May 16.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101190741 Publication Model: Electronic Cited Medium: Internet ISSN: 1479-5876 (Electronic) Linking ISSN: 14795876 NLM ISO Abbreviation: J Transl Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: EDL6D, a bioactive peptide phenocopying SHBG-associated metabolic effects: a new preclinical lead compound for treating the metabolic dysfunction-associated fatty liver disease.
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  Data: <searchLink fieldCode="AU" term="%22Alvarez-Guaita+A%22">Alvarez-Guaita A</searchLink>; Diabetes and Metabolism Research Unit, Vall d' Hebron Institut de Recerca (VHIR), Universitat Autònoma de Barcelona and CIBERDEM (ISCIII), Pg Vall d'Hebron 119-129, Barcelona, 08035, Spain.; Endolipid Therapeutics S.L, Vall Hebron Institut de Recerca (VHIR), Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Cabrera-Serra+J%22">Cabrera-Serra J</searchLink>; Diabetes and Metabolism Research Unit, Vall d' Hebron Institut de Recerca (VHIR), Universitat Autònoma de Barcelona and CIBERDEM (ISCIII), Pg Vall d'Hebron 119-129, Barcelona, 08035, Spain.<br /><searchLink fieldCode="AU" term="%22Perez-Gonzalez+B%22">Perez-Gonzalez B</searchLink>; Diabetes and Metabolism Research Unit, Vall d' Hebron Institut de Recerca (VHIR), Universitat Autònoma de Barcelona and CIBERDEM (ISCIII), Pg Vall d'Hebron 119-129, Barcelona, 08035, Spain.; Endolipid Therapeutics S.L, Vall Hebron Institut de Recerca (VHIR), Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Salcedo-Allende+MT%22">Salcedo-Allende MT</searchLink>; Human Pathology Department, Vall d'Hebron University Hospital, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Fuertes-Rioja+L%22">Fuertes-Rioja L</searchLink>; Diabetes and Metabolism Research Unit, Vall d' Hebron Institut de Recerca (VHIR), Universitat Autònoma de Barcelona and CIBERDEM (ISCIII), Pg Vall d'Hebron 119-129, Barcelona, 08035, Spain.<br /><searchLink fieldCode="AU" term="%22Ramos-Perez+L%22">Ramos-Perez L</searchLink>; Diabetes and Metabolism Research Unit, Vall d' Hebron Institut de Recerca (VHIR), Universitat Autònoma de Barcelona and CIBERDEM (ISCIII), Pg Vall d'Hebron 119-129, Barcelona, 08035, Spain.<br /><searchLink fieldCode="AU" term="%22Hernandez+C%22">Hernandez C</searchLink>; Diabetes and Metabolism Research Unit, Vall d' Hebron Institut de Recerca (VHIR), Universitat Autònoma de Barcelona and CIBERDEM (ISCIII), Pg Vall d'Hebron 119-129, Barcelona, 08035, Spain.<br /><searchLink fieldCode="AU" term="%22Simó+R%22">Simó R</searchLink>; Diabetes and Metabolism Research Unit, Vall d' Hebron Institut de Recerca (VHIR), Universitat Autònoma de Barcelona and CIBERDEM (ISCIII), Pg Vall d'Hebron 119-129, Barcelona, 08035, Spain.; Endolipid Therapeutics S.L, Vall Hebron Institut de Recerca (VHIR), Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Selva+DM%22">Selva DM</searchLink>; Diabetes and Metabolism Research Unit, Vall d' Hebron Institut de Recerca (VHIR), Universitat Autònoma de Barcelona and CIBERDEM (ISCIII), Pg Vall d'Hebron 119-129, Barcelona, 08035, Spain. david.martinez.selva@vhir.org.; Endolipid Therapeutics S.L, Vall Hebron Institut de Recerca (VHIR), Barcelona, Spain. david.martinez.selva@vhir.org.
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  Data: <searchLink fieldCode="JN" term="%22101190741%22">Journal of translational medicine</searchLink> [J Transl Med] 2026 May 16; Vol. 24 (1). <i>Date of Electronic Publication: </i>2026 May 16.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central%22">BioMed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101190741 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1479-5876 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2214795876%22">14795876 </searchLink><i>NLM ISO Abbreviation: </i>J Transl Med <i>Subsets: </i>MEDLINE
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              Text: 2026 May 16
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