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Effect of ancestry and shared genetic architecture of serious mental illness on symptoms and cognition in an admixed Latin American population.

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Title: Effect of ancestry and shared genetic architecture of serious mental illness on symptoms and cognition in an admixed Latin American population.
Authors: Lopera-Maya E; Center for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, University of California Los Angeles, Los Angeles, USA., Service SK; Center for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, University of California Los Angeles, Los Angeles, USA., Díaz-Zuluaga AM; Center for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, University of California Los Angeles, Los Angeles, USA., Ramírez MC; Department of Mental Health and Human Behavior, University of Caldas, Manizales, Colombia., Mejia JC; Research Group in Psychiatry GIPSI, Department of Psychiatry, School of Medicine, Universidad de Antioquia, Medellin, Colombia., Valencia J; Research Group in Psychiatry GIPSI, Department of Psychiatry, School of Medicine, Universidad de Antioquia, Medellin, Colombia., Teshiba T; Center for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, University of California Los Angeles, Los Angeles, USA., Ramirez AM; Center for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, University of California Los Angeles, Los Angeles, USA., De la Hoz JF; Center for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, University of California Los Angeles, Los Angeles, USA.; Psychiatric and Neurodevelopmental Genetics Unit, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Valdez J; Center for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, University of California Los Angeles, Los Angeles, USA., Umanes MM; Center for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, University of California Los Angeles, Los Angeles, USA., Moore TM; Department of Psychiatry, University of Pennsylvania School of Medicine; Philadelphia, USA., Chapman S; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA.; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Neale BM; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA.; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Bearden CE; Center for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, University of California Los Angeles, Los Angeles, USA.; Department of Psychology, University of California Los Angeles, Los Angeles, USA., Escobar JI; Department of Psychiatry, Rutgers Robert Wood Johnson Medical School, New Brunswick, USA., Gur RC; Department of Psychiatry, University of Pennsylvania School of Medicine; Philadelphia, USA., Reus VI; Department of Psychiatry and Behavioral Sciences, University of California San Francisco, San Francisco, USA., Sabatti C; Departments of Biomedical Data Science and Statistics, Stanford University, Stanford, USA., Loohuis LO; Center for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, University of California Los Angeles, Los Angeles, USA., Jaramillo CL; Department of Psychiatry, University of Antioquía, Medellín, Colombia., Freimer NB; Center for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, University of California Los Angeles, Los Angeles, USA.
Source: MedRxiv : the preprint server for health sciences [medRxiv] 2026 May 07. Date of Electronic Publication: 2026 May 07.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101767986 Publication Model: Electronic Cited Medium: Internet NLM ISO Abbreviation: medRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
FullText Text:
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  Data: Effect of ancestry and shared genetic architecture of serious mental illness on symptoms and cognition in an admixed Latin American population.
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  Data: <searchLink fieldCode="AU" term="%22Lopera-Maya+E%22">Lopera-Maya E</searchLink>; Center for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, University of California Los Angeles, Los Angeles, USA.<br /><searchLink fieldCode="AU" term="%22Service+SK%22">Service SK</searchLink>; Center for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, University of California Los Angeles, Los Angeles, USA.<br /><searchLink fieldCode="AU" term="%22Díaz-Zuluaga+AM%22">Díaz-Zuluaga AM</searchLink>; Center for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, University of California Los Angeles, Los Angeles, USA.<br /><searchLink fieldCode="AU" term="%22Ramírez+MC%22">Ramírez MC</searchLink>; Department of Mental Health and Human Behavior, University of Caldas, Manizales, Colombia.<br /><searchLink fieldCode="AU" term="%22Mejia+JC%22">Mejia JC</searchLink>; Research Group in Psychiatry GIPSI, Department of Psychiatry, School of Medicine, Universidad de Antioquia, Medellin, Colombia.<br /><searchLink fieldCode="AU" term="%22Valencia+J%22">Valencia J</searchLink>; Research Group in Psychiatry GIPSI, Department of Psychiatry, School of Medicine, Universidad de Antioquia, Medellin, Colombia.<br /><searchLink fieldCode="AU" term="%22Teshiba+T%22">Teshiba T</searchLink>; Center for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, University of California Los Angeles, Los Angeles, USA.<br /><searchLink fieldCode="AU" term="%22Ramirez+AM%22">Ramirez AM</searchLink>; Center for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, University of California Los Angeles, Los Angeles, USA.<br /><searchLink fieldCode="AU" term="%22De+la+Hoz+JF%22">De la Hoz JF</searchLink>; Center for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, University of California Los Angeles, Los Angeles, USA.; Psychiatric and Neurodevelopmental Genetics Unit, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Valdez+J%22">Valdez J</searchLink>; Center for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, University of California Los Angeles, Los Angeles, USA.<br /><searchLink fieldCode="AU" term="%22Umanes+MM%22">Umanes MM</searchLink>; Center for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, University of California Los Angeles, Los Angeles, USA.<br /><searchLink fieldCode="AU" term="%22Moore+TM%22">Moore TM</searchLink>; Department of Psychiatry, University of Pennsylvania School of Medicine; Philadelphia, USA.<br /><searchLink fieldCode="AU" term="%22Chapman+S%22">Chapman S</searchLink>; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA.; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Neale+BM%22">Neale BM</searchLink>; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA.; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Bearden+CE%22">Bearden CE</searchLink>; Center for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, University of California Los Angeles, Los Angeles, USA.; Department of Psychology, University of California Los Angeles, Los Angeles, USA.<br /><searchLink fieldCode="AU" term="%22Escobar+JI%22">Escobar JI</searchLink>; Department of Psychiatry, Rutgers Robert Wood Johnson Medical School, New Brunswick, USA.<br /><searchLink fieldCode="AU" term="%22Gur+RC%22">Gur RC</searchLink>; Department of Psychiatry, University of Pennsylvania School of Medicine; Philadelphia, USA.<br /><searchLink fieldCode="AU" term="%22Reus+VI%22">Reus VI</searchLink>; Department of Psychiatry and Behavioral Sciences, University of California San Francisco, San Francisco, USA.<br /><searchLink fieldCode="AU" term="%22Sabatti+C%22">Sabatti C</searchLink>; Departments of Biomedical Data Science and Statistics, Stanford University, Stanford, USA.<br /><searchLink fieldCode="AU" term="%22Loohuis+LO%22">Loohuis LO</searchLink>; Center for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, University of California Los Angeles, Los Angeles, USA.<br /><searchLink fieldCode="AU" term="%22Jaramillo+CL%22">Jaramillo CL</searchLink>; Department of Psychiatry, University of Antioquía, Medellín, Colombia.<br /><searchLink fieldCode="AU" term="%22Freimer+NB%22">Freimer NB</searchLink>; Center for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, University of California Los Angeles, Los Angeles, USA.
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  Data: <searchLink fieldCode="JN" term="%22101767986%22">MedRxiv : the preprint server for health sciences</searchLink> [medRxiv] 2026 May 07. <i>Date of Electronic Publication: </i>2026 May 07.
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  Data: <i>Country of Publication: </i>United States <i>NLM ID: </i>101767986 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>NLM ISO Abbreviation: </i>medRxiv <i>Subsets: </i>PubMed not MEDLINE
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        Value: 10.64898/2026.05.05.26351986
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        Text: English
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