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Germline polygenic score for prostate cancer aggressiveness.

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Title: Germline polygenic score for prostate cancer aggressiveness.
Authors: Xu G; Research Service, VA San Diego Healthcare System, San Diego, CA, USA.; Department of Radiation Medicine and Applied Sciences, University of California San Diego, La Jolla, CA, USA., Karunamuni R; Research Service, VA San Diego Healthcare System, San Diego, CA, USA.; Department of Radiation Medicine and Applied Sciences, University of California San Diego, La Jolla, CA, USA., Dornisch AM; Department of Radiation Medicine and Applied Sciences, University of California San Diego, La Jolla, CA, USA., Brunette CA; VA Boston Healthcare System, Boston, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA., Danowski ME; VA Boston Healthcare System, Boston, MA, USA., Desai H; Department of Medicine, Hematology-Oncology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA., Dochtermann D; Center for Data and Computational Sciences, VA Boston Healthcare System, Boston, MA, USA., Garraway IP; Division of Urology, VA Greater Los Angeles Healthcare System, Los Angeles, CA, USA.; Department of Urology, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA., Hauger RL; Research Service, VA San Diego Healthcare System, San Diego, CA, USA.; Center for Behavior Genetics of Aging, School of Medicine, UC San Diego, La Jolla, CA, USA., Kibel AS; Harvard Medical School, Boston, MA, USA.; Department of Urology, Mass General Brigham, Harvard Medical School, Boston, MA, USA., Lynch JA; VA Informatics and Computing Infrastructure, VA Salt Lake City Healthcare System, Salt Lake City, UT, USA.; Department of Internal Medicine, University of Utah School of Medicine, Salt Lake City, CA, USA., Pyarajan S; Center for Data and Computational Sciences, VA Boston Healthcare System, Boston, MA, USA., Rose BS; Research Service, VA San Diego Healthcare System, San Diego, CA, USA.; Department of Radiation Medicine and Applied Sciences, University of California San Diego, La Jolla, CA, USA., Teerlink CC; VA Informatics and Computing Infrastructure, VA Salt Lake City Healthcare System, Salt Lake City, UT, USA.; Department of Internal Medicine, University of Utah School of Medicine, Salt Lake City, CA, USA., Andreassen OA; Center for Precision Psychiatry, Oslo University Hospital and University of Oslo, Oslo, Norway., Dale AM; Center for Multimodal Imaging and Genetics, University of California, San Diego, La Jolla, CA, USA.; Department of Radiology, University of California, San Diego, La Jolla, CA, USA.; Department of Neurosciences, University of California, San Diego, La Jolla, CA, USA.; Halıcıoğlu Data Science Institute, University of California San Diego, La Jolla, California, USA.; NORMENT, KG Jebsen Centre, Oslo University Hospital and University of Oslo, Oslo, Norway., Donovan JL; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK., Hamdy F; Nuffield Department of Surgical Sciences, University of Oxford, Oxford, UK.; Cancer Research UK Oxford Centre, Old Road Campus Research Building, Oxford OX2 7DQ, UK., Kachuri L; Department of Epidemiology and Population Health, Stanford University, Stanford, CA, USA., Lane A; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK., Martin RM; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.; National Institute for Health Research (NIHR) Bristol Biomedical Research Centre, University Hospitals Bristol and Weston NHS Foundation Trust and University of Bristol, Bristol, UK., Mills IG; Nuffield Department of Surgical Sciences, University of Oxford, Oxford, UK., Neal DE; Nuffield Department of Surgical Sciences, University of Oxford, Oxford, UK.; University of Cambridge, Department of Oncology, Box 279, Addenbrooke's Hospital, Hills Road, Cambridge CB2 0QQ, UK.; Cancer Research UK, Cambridge Research Institute, Li Ka Shing Centre, Cambridge, CB2 0RE, UK., Turner EL; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK., Witte JS; Department of Epidemiology and Population Health, Stanford University, Stanford, CA, USA., Schleutker J; Institute of Biomedicine, University of Turku, Finland.; Department of Genomics, Laboratory Division, Turku University Hospital, PO Box 52, 20521 Turku, Finland., Pashayan N; Department of Public Health & Primary Care, Strangeways Research Laboratory, Worts Causeway, Cambridge, CB1 8RN., Batra J; School of Biomedical Science, Faculty of Health Sciences and Medicine, Bond University, Gold Coast, Queensland, Australia.; Centre for Genomics and Personalised Health, School of Biomedical Sciences, Faculty of Health, Queensland University of Technology, Brisbane, Queensland, Australia.; Translational Research Institute, Brisbane, Queensland 4102, Australia., Nordestgaard BG; Faculty of Health and Medical Sciences, University of Copenhagen, 2200 Copenhagen, Denmark.; Department of Clinical Biochemistry, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev, 2200 Copenhagen, Denmark., Hamilton RJ; Dept. of Surgical Oncology, Princess Margaret Cancer Centre, Toronto ON M5G 2M9, Canada.; Dept. of Surgery (Urology), University of Toronto, Canada., Wolk A; Institute of Environmental Medicine, Karolinska Institutet, 177 77 Stockholm, Sweden., Albanes D; Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Bethesda, Maryland, 20892, USA., Atkins J; Cancer Epidemiology Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK., Blot WJ; Division of Epidemiology, Department of Medicine, Vanderbilt University Medical Center, 2525 West End Avenue, Suite 800, Nashville, TN 37232 USA.; International Epidemiology Institute, Rockville, MD 20850, USA., Mucci LA; Department of Epidemiology, Harvard T. H. Chan School of Public Health, Boston, MA 02115, USA., Nielsen SF; Department of Clinical Biochemistry, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev, 2200 Copenhagen, Denmark.; Faculty of Health and Medical Sciences, University of Copenhagen, 2200 Copenhagen, Denmark., Cussenot O; Sorbonne Universite, GRC n°5, AP-HP, Tenon Hospital, 4 rue de la Chine, F-75020 Paris, France.; CeRePP, Tenon Hospital, F-75020 Paris, France., Berndt SI; Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Bethesda, Maryland, 20892, USA., Koutros S; Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Bethesda, Maryland, 20892, USA., Sørensen KD; Department of Molecular Medicine, Aarhus University Hospital, Palle Juul-Jensen Boulevard 99, 8200 Aarhus N, Denmark.; Department of Clinical Medicine, Aarhus University, DK-8200 Aarhus N., Cybulski C; International Hereditary Cancer Center, Department of Genetics and Pathology, Pomeranian Medical University, 70-115 Szczecin, Poland., Menegaux F; Exposome and Heredity, CESP (UMR 1018), Faculté de Médecine, Université Paris-Saclay, Inserm, Gustave Roussy, Villejuif., Park JY; Department of Cancer Epidemiology, Moffitt Cancer Center, 12902 Magnolia Drive, Tampa, FL 33612, USA., MacInnis RJ; Cancer Epidemiology Division, Cancer Council Victoria, 200 Victoria Parade, East Melbourne, VIC, 3002, Australia.; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Grattan Street, Parkville, VIC 3010, Australia., Rosenstein BS; Department of Radiation Oncology and Department of Genetics and Genomic Sciences, Box 1236, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, New York, NY 10029, USA., Lu YJ; Centre for Cancer Biomarker and Biotherapeutics, Barts Cancer Institute, Queen Mary University of London, John Vane Science Centre, Charterhouse Square, London, EC1M 6BQ, UK., Watya S; Uro Care, Kampala, Uganda., Vega A; Fundación Pública Galega Medicina Xenómica, Santiago de Compostela, 15706, Spain.; Instituto de Investigación Sanitaria de Santiago de Compostela, Santiago de Compostela, 15706, Spain.; Centro de Investigación en Red de Enfermedades Raras (CIBERER), Spain., Kogevinas M; ISGlobal, Barcelona, Spain.; IMIM (Hospital del Mar Medical Research Institute), Barcelona, Spain.; Universitat Pompeu Fabra (UPF), Barcelona, Spain.; CIBER Epidemiología y Salud Pública (CIBERESP), 28029 Madrid, Spain., Wiklund F; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, SE-171 77 Stockholm, Sweden., Plym A; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, SE-171 77 Stockholm, Sweden.; Department of Epidemiology, Harvard T. H. Chan School of Public Health, Boston, MA 02115, USA., Teixeira MR; Department of Laboratory Genetics, Portuguese Oncology Institute of Porto (IPO Porto) / Porto Comprehensive Cancer Center, Porto, Portugal.; Cancer Genetics Group, IPO Porto Research Center (CI-IPOP) / RISE@CI-IPOP (Health Research Network), Portuguese Oncology Institute of Porto (IPO Porto) / Porto Comprehensive Cancer Center, Porto, Portugal.; School of Medicine and Biomedical Sciences (ICBAS), University of Porto, Porto, Portugal., Multigner L; Univ Rennes, Inserm, EHESP, Irset (Institut de recherche en santé, environnement et travail) - UMR_S 1085, Rennes, France., Leach RJ; Department of Cell Systems and Anatomy, Mays Cancer Center, University of Texas Health Science Center at San Antonio, San Antonio Texas., Brenner H; Cancer Prevention Graduate School, German Cancer Research Center (DKFZ), D-69120, Heidelberg, Germany.; Network Aging Research (NAR), Heidelberg University, D-69120 Heidelberg, Germany., John EM; Departments of Epidemiology & Population Health and of Medicine, Division of Oncology, Stanford Cancer Institute, Stanford University School of Medicine, Stanford, CA 94304 USA., Kaneva R; Molecular Medicine Center, Department of Medical Chemistry and Biochemistry, Medical University of Sofia, Sofia, 2 Zdrave Str., 1431 Sofia, Bulgaria., Logothetis CJ; The University of Texas M. D. Anderson Cancer Center, Department of Genitourinary Medical Oncology, 1515 Holcombe Blvd., Houston, TX 77030, USA., Neuhausen SL; Department of Population Sciences, Beckman Research Institute of the City of Hope, 1500 East Duarte Road, Duarte, CA 91010., Ost P; Department of human structure and repair, Ghent University, Ghent, Belgium., Razack A; Department of Surgery, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia., Fowke JH; Division of Epidemiology, Department of Preventive Medicine, University of Tennessee Health Science Center, Memphis, TN 38163., Gamulin M; Department of Oncology, University Hospital Centre Zagreb, University of Zagreb, School of Medicine, 10 000 Zagreb, Croatia., Usmani N; Department of Oncology, Cross Cancer Institute, University of Alberta, 11560 University Avenue, Edmonton, Alberta, Canada T6G 1Z2.; Division of Radiation Oncology, Cross Cancer Institute, 11560 University Avenue, Edmonton, Alberta, Canada T6G 1Z2., Claessens F; Molecular Endocrinology Laboratory, Department of Cellular and Molecular Medicine, KU Leuven, BE-3000, Belgium., Castelao JE; Genetic Oncology Unit, CHUVI Hospital, Complexo Hospitalario Universitario de Vigo, Instituto de Investigación Biomédica Galicia Sur (IISGS), 36204, Vigo (Pontevedra), Spain., Petrovics G; Uniformed Services University, 4301 Jones Bridge Rd, Bethesda, MD 20814, USA.; Center for Prostate Disease Research, 6720A Rockledge Drive, Suite 300, Bethesda, MD 20817, USA., Parent MÉ; Epidemiology and Biostatistics Unit, Centre Armand-Frappier Santé Biotechnologie, Institut national de la recherche scientifique, 531 Boul. des Prairies, Laval, QC, Canada H7V 1B7.; Department of Social and Preventive Medicine, School of Public Health, University of Montreal, Montreal, QC, Canada., Hu JJ; The University of Miami School of Medicine, Sylvester Comprehensive Cancer Center, 1120 NW 14th Street, CRB 1511, Miami, Florida 33136, USA., Zheng W; Division of Epidemiology, Department of Medicine, Vanderbilt University Medical Center, 2525 West End Avenue, Suite 800, Nashville, TN 37232 USA., Kote-Jarai Z; The Institute of Cancer Research, London, SM2 5NG, UK., Eeles RA; The Institute of Cancer Research, London, SM2 5NG, UK.; Royal Marsden NHS Foundation Trust, London, SW3 6JJ, UK., Maxwell KN; Corporal Michael Crescenz Veterans Affairs Medical Center, Philadelphia, PA, USA.; Department of Medicine - Hematology/Oncology, Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA, USA., Vassy JL; VA Boston Healthcare System, Boston, MA, USA.; Division of General Internal Medicine and Primary Care, VA Boston Healthcare System, Boston, MA, USA., Seibert TM; Research Service, VA San Diego Healthcare System, San Diego, CA, USA.; Department of Radiation Medicine and Applied Sciences, University of California San Diego, La Jolla, CA, USA.; Departments of Radiology, University of California San Diego, La Jolla, CA, USA.; Department of Bioengineering, University of California San Diego, La Jolla, CA, USA.; Department of Urology, University of California San Diego, La Jolla, CA, USA.; NORMENT, KG Jebsen Centre, Oslo University Hospital and University of Oslo, Oslo, Norway.
Corporate Authors: Australian Prostate Cancer BioResource (APCB), NC-LA PCaP Investigators, IMPACT Study Steering Committee and Collaborators, Profile Study Steering Committee, UKGPCS collaborators, PRACTICAL Consortium, VA Million Veteran Program
Source: MedRxiv : the preprint server for health sciences [medRxiv] 2026 May 13. Date of Electronic Publication: 2026 May 13.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101767986 Publication Model: Electronic Cited Medium: Internet NLM ISO Abbreviation: medRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 42145622
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
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Items – Name: Title
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  Data: Germline polygenic score for prostate cancer aggressiveness.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Xu+G%22">Xu G</searchLink>; Research Service, VA San Diego Healthcare System, San Diego, CA, USA.; Department of Radiation Medicine and Applied Sciences, University of California San Diego, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Karunamuni+R%22">Karunamuni R</searchLink>; Research Service, VA San Diego Healthcare System, San Diego, CA, USA.; Department of Radiation Medicine and Applied Sciences, University of California San Diego, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Dornisch+AM%22">Dornisch AM</searchLink>; Department of Radiation Medicine and Applied Sciences, University of California San Diego, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Brunette+CA%22">Brunette CA</searchLink>; VA Boston Healthcare System, Boston, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Danowski+ME%22">Danowski ME</searchLink>; VA Boston Healthcare System, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Desai+H%22">Desai H</searchLink>; Department of Medicine, Hematology-Oncology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA.<br /><searchLink fieldCode="AU" term="%22Dochtermann+D%22">Dochtermann D</searchLink>; Center for Data and Computational Sciences, VA Boston Healthcare System, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Garraway+IP%22">Garraway IP</searchLink>; Division of Urology, VA Greater Los Angeles Healthcare System, Los Angeles, CA, USA.; Department of Urology, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Hauger+RL%22">Hauger RL</searchLink>; Research Service, VA San Diego Healthcare System, San Diego, CA, USA.; Center for Behavior Genetics of Aging, School of Medicine, UC San Diego, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Kibel+AS%22">Kibel AS</searchLink>; Harvard Medical School, Boston, MA, USA.; Department of Urology, Mass General Brigham, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Lynch+JA%22">Lynch JA</searchLink>; VA Informatics and Computing Infrastructure, VA Salt Lake City Healthcare System, Salt Lake City, UT, USA.; Department of Internal Medicine, University of Utah School of Medicine, Salt Lake City, CA, USA.<br /><searchLink fieldCode="AU" term="%22Pyarajan+S%22">Pyarajan S</searchLink>; Center for Data and Computational Sciences, VA Boston Healthcare System, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Rose+BS%22">Rose BS</searchLink>; Research Service, VA San Diego Healthcare System, San Diego, CA, USA.; Department of Radiation Medicine and Applied Sciences, University of California San Diego, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Teerlink+CC%22">Teerlink CC</searchLink>; VA Informatics and Computing Infrastructure, VA Salt Lake City Healthcare System, Salt Lake City, UT, USA.; Department of Internal Medicine, University of Utah School of Medicine, Salt Lake City, CA, USA.<br /><searchLink fieldCode="AU" term="%22Andreassen+OA%22">Andreassen OA</searchLink>; Center for Precision Psychiatry, Oslo University Hospital and University of Oslo, Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22Dale+AM%22">Dale AM</searchLink>; Center for Multimodal Imaging and Genetics, University of California, San Diego, La Jolla, CA, USA.; Department of Radiology, University of California, San Diego, La Jolla, CA, USA.; Department of Neurosciences, University of California, San Diego, La Jolla, CA, USA.; Halıcıoğlu Data Science Institute, University of California San Diego, La Jolla, California, USA.; NORMENT, KG Jebsen Centre, Oslo University Hospital and University of Oslo, Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22Donovan+JL%22">Donovan JL</searchLink>; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.<br /><searchLink fieldCode="AU" term="%22Hamdy+F%22">Hamdy F</searchLink>; Nuffield Department of Surgical Sciences, University of Oxford, Oxford, UK.; Cancer Research UK Oxford Centre, Old Road Campus Research Building, Oxford OX2 7DQ, UK.<br /><searchLink fieldCode="AU" term="%22Kachuri+L%22">Kachuri L</searchLink>; Department of Epidemiology and Population Health, Stanford University, Stanford, CA, USA.<br /><searchLink fieldCode="AU" term="%22Lane+A%22">Lane A</searchLink>; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.<br /><searchLink fieldCode="AU" term="%22Martin+RM%22">Martin RM</searchLink>; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.; National Institute for Health Research (NIHR) Bristol Biomedical Research Centre, University Hospitals Bristol and Weston NHS Foundation Trust and University of Bristol, Bristol, UK.<br /><searchLink fieldCode="AU" term="%22Mills+IG%22">Mills IG</searchLink>; Nuffield Department of Surgical Sciences, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Neal+DE%22">Neal DE</searchLink>; Nuffield Department of Surgical Sciences, University of Oxford, Oxford, UK.; University of Cambridge, Department of Oncology, Box 279, Addenbrooke's Hospital, Hills Road, Cambridge CB2 0QQ, UK.; Cancer Research UK, Cambridge Research Institute, Li Ka Shing Centre, Cambridge, CB2 0RE, UK.<br /><searchLink fieldCode="AU" term="%22Turner+EL%22">Turner EL</searchLink>; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.<br /><searchLink fieldCode="AU" term="%22Witte+JS%22">Witte JS</searchLink>; Department of Epidemiology and Population Health, Stanford University, Stanford, CA, USA.<br /><searchLink fieldCode="AU" term="%22Schleutker+J%22">Schleutker J</searchLink>; Institute of Biomedicine, University of Turku, Finland.; Department of Genomics, Laboratory Division, Turku University Hospital, PO Box 52, 20521 Turku, Finland.<br /><searchLink fieldCode="AU" term="%22Pashayan+N%22">Pashayan N</searchLink>; Department of Public Health & Primary Care, Strangeways Research Laboratory, Worts Causeway, Cambridge, CB1 8RN.<br /><searchLink fieldCode="AU" term="%22Batra+J%22">Batra J</searchLink>; School of Biomedical Science, Faculty of Health Sciences and Medicine, Bond University, Gold Coast, Queensland, Australia.; Centre for Genomics and Personalised Health, School of Biomedical Sciences, Faculty of Health, Queensland University of Technology, Brisbane, Queensland, Australia.; Translational Research Institute, Brisbane, Queensland 4102, Australia.<br /><searchLink fieldCode="AU" term="%22Nordestgaard+BG%22">Nordestgaard BG</searchLink>; Faculty of Health and Medical Sciences, University of Copenhagen, 2200 Copenhagen, Denmark.; Department of Clinical Biochemistry, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev, 2200 Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Hamilton+RJ%22">Hamilton RJ</searchLink>; Dept. of Surgical Oncology, Princess Margaret Cancer Centre, Toronto ON M5G 2M9, Canada.; Dept. of Surgery (Urology), University of Toronto, Canada.<br /><searchLink fieldCode="AU" term="%22Wolk+A%22">Wolk A</searchLink>; Institute of Environmental Medicine, Karolinska Institutet, 177 77 Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Albanes+D%22">Albanes D</searchLink>; Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Bethesda, Maryland, 20892, USA.<br /><searchLink fieldCode="AU" term="%22Atkins+J%22">Atkins J</searchLink>; Cancer Epidemiology Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Blot+WJ%22">Blot WJ</searchLink>; Division of Epidemiology, Department of Medicine, Vanderbilt University Medical Center, 2525 West End Avenue, Suite 800, Nashville, TN 37232 USA.; International Epidemiology Institute, Rockville, MD 20850, USA.<br /><searchLink fieldCode="AU" term="%22Mucci+LA%22">Mucci LA</searchLink>; Department of Epidemiology, Harvard T. H. Chan School of Public Health, Boston, MA 02115, USA.<br /><searchLink fieldCode="AU" term="%22Nielsen+SF%22">Nielsen SF</searchLink>; Department of Clinical Biochemistry, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev, 2200 Copenhagen, Denmark.; Faculty of Health and Medical Sciences, University of Copenhagen, 2200 Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Cussenot+O%22">Cussenot O</searchLink>; Sorbonne Universite, GRC n°5, AP-HP, Tenon Hospital, 4 rue de la Chine, F-75020 Paris, France.; CeRePP, Tenon Hospital, F-75020 Paris, France.<br /><searchLink fieldCode="AU" term="%22Berndt+SI%22">Berndt SI</searchLink>; Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Bethesda, Maryland, 20892, USA.<br /><searchLink fieldCode="AU" term="%22Koutros+S%22">Koutros S</searchLink>; Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Bethesda, Maryland, 20892, USA.<br /><searchLink fieldCode="AU" term="%22Sørensen+KD%22">Sørensen KD</searchLink>; Department of Molecular Medicine, Aarhus University Hospital, Palle Juul-Jensen Boulevard 99, 8200 Aarhus N, Denmark.; Department of Clinical Medicine, Aarhus University, DK-8200 Aarhus N.<br /><searchLink fieldCode="AU" term="%22Cybulski+C%22">Cybulski C</searchLink>; International Hereditary Cancer Center, Department of Genetics and Pathology, Pomeranian Medical University, 70-115 Szczecin, Poland.<br /><searchLink fieldCode="AU" term="%22Menegaux+F%22">Menegaux F</searchLink>; Exposome and Heredity, CESP (UMR 1018), Faculté de Médecine, Université Paris-Saclay, Inserm, Gustave Roussy, Villejuif.<br /><searchLink fieldCode="AU" term="%22Park+JY%22">Park JY</searchLink>; Department of Cancer Epidemiology, Moffitt Cancer Center, 12902 Magnolia Drive, Tampa, FL 33612, USA.<br /><searchLink fieldCode="AU" term="%22MacInnis+RJ%22">MacInnis RJ</searchLink>; Cancer Epidemiology Division, Cancer Council Victoria, 200 Victoria Parade, East Melbourne, VIC, 3002, Australia.; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Grattan Street, Parkville, VIC 3010, Australia.<br /><searchLink fieldCode="AU" term="%22Rosenstein+BS%22">Rosenstein BS</searchLink>; Department of Radiation Oncology and Department of Genetics and Genomic Sciences, Box 1236, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, New York, NY 10029, USA.<br /><searchLink fieldCode="AU" term="%22Lu+YJ%22">Lu YJ</searchLink>; Centre for Cancer Biomarker and Biotherapeutics, Barts Cancer Institute, Queen Mary University of London, John Vane Science Centre, Charterhouse Square, London, EC1M 6BQ, UK.<br /><searchLink fieldCode="AU" term="%22Watya+S%22">Watya S</searchLink>; Uro Care, Kampala, Uganda.<br /><searchLink fieldCode="AU" term="%22Vega+A%22">Vega A</searchLink>; Fundación Pública Galega Medicina Xenómica, Santiago de Compostela, 15706, Spain.; Instituto de Investigación Sanitaria de Santiago de Compostela, Santiago de Compostela, 15706, Spain.; Centro de Investigación en Red de Enfermedades Raras (CIBERER), Spain.<br /><searchLink fieldCode="AU" term="%22Kogevinas+M%22">Kogevinas M</searchLink>; ISGlobal, Barcelona, Spain.; IMIM (Hospital del Mar Medical Research Institute), Barcelona, Spain.; Universitat Pompeu Fabra (UPF), Barcelona, Spain.; CIBER Epidemiología y Salud Pública (CIBERESP), 28029 Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Wiklund+F%22">Wiklund F</searchLink>; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, SE-171 77 Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Plym+A%22">Plym A</searchLink>; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, SE-171 77 Stockholm, Sweden.; Department of Epidemiology, Harvard T. H. Chan School of Public Health, Boston, MA 02115, USA.<br /><searchLink fieldCode="AU" term="%22Teixeira+MR%22">Teixeira MR</searchLink>; Department of Laboratory Genetics, Portuguese Oncology Institute of Porto (IPO Porto) / Porto Comprehensive Cancer Center, Porto, Portugal.; Cancer Genetics Group, IPO Porto Research Center (CI-IPOP) / RISE@CI-IPOP (Health Research Network), Portuguese Oncology Institute of Porto (IPO Porto) / Porto Comprehensive Cancer Center, Porto, Portugal.; School of Medicine and Biomedical Sciences (ICBAS), University of Porto, Porto, Portugal.<br /><searchLink fieldCode="AU" term="%22Multigner+L%22">Multigner L</searchLink>; Univ Rennes, Inserm, EHESP, Irset (Institut de recherche en santé, environnement et travail) - UMR_S 1085, Rennes, France.<br /><searchLink fieldCode="AU" term="%22Leach+RJ%22">Leach RJ</searchLink>; Department of Cell Systems and Anatomy, Mays Cancer Center, University of Texas Health Science Center at San Antonio, San Antonio Texas.<br /><searchLink fieldCode="AU" term="%22Brenner+H%22">Brenner H</searchLink>; Cancer Prevention Graduate School, German Cancer Research Center (DKFZ), D-69120, Heidelberg, Germany.; Network Aging Research (NAR), Heidelberg University, D-69120 Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22John+EM%22">John EM</searchLink>; Departments of Epidemiology & Population Health and of Medicine, Division of Oncology, Stanford Cancer Institute, Stanford University School of Medicine, Stanford, CA 94304 USA.<br /><searchLink fieldCode="AU" term="%22Kaneva+R%22">Kaneva R</searchLink>; Molecular Medicine Center, Department of Medical Chemistry and Biochemistry, Medical University of Sofia, Sofia, 2 Zdrave Str., 1431 Sofia, Bulgaria.<br /><searchLink fieldCode="AU" term="%22Logothetis+CJ%22">Logothetis CJ</searchLink>; The University of Texas M. D. Anderson Cancer Center, Department of Genitourinary Medical Oncology, 1515 Holcombe Blvd., Houston, TX 77030, USA.<br /><searchLink fieldCode="AU" term="%22Neuhausen+SL%22">Neuhausen SL</searchLink>; Department of Population Sciences, Beckman Research Institute of the City of Hope, 1500 East Duarte Road, Duarte, CA 91010.<br /><searchLink fieldCode="AU" term="%22Ost+P%22">Ost P</searchLink>; Department of human structure and repair, Ghent University, Ghent, Belgium.<br /><searchLink fieldCode="AU" term="%22Razack+A%22">Razack A</searchLink>; Department of Surgery, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia.<br /><searchLink fieldCode="AU" term="%22Fowke+JH%22">Fowke JH</searchLink>; Division of Epidemiology, Department of Preventive Medicine, University of Tennessee Health Science Center, Memphis, TN 38163.<br /><searchLink fieldCode="AU" term="%22Gamulin+M%22">Gamulin M</searchLink>; Department of Oncology, University Hospital Centre Zagreb, University of Zagreb, School of Medicine, 10 000 Zagreb, Croatia.<br /><searchLink fieldCode="AU" term="%22Usmani+N%22">Usmani N</searchLink>; Department of Oncology, Cross Cancer Institute, University of Alberta, 11560 University Avenue, Edmonton, Alberta, Canada T6G 1Z2.; Division of Radiation Oncology, Cross Cancer Institute, 11560 University Avenue, Edmonton, Alberta, Canada T6G 1Z2.<br /><searchLink fieldCode="AU" term="%22Claessens+F%22">Claessens F</searchLink>; Molecular Endocrinology Laboratory, Department of Cellular and Molecular Medicine, KU Leuven, BE-3000, Belgium.<br /><searchLink fieldCode="AU" term="%22Castelao+JE%22">Castelao JE</searchLink>; Genetic Oncology Unit, CHUVI Hospital, Complexo Hospitalario Universitario de Vigo, Instituto de Investigación Biomédica Galicia Sur (IISGS), 36204, Vigo (Pontevedra), Spain.<br /><searchLink fieldCode="AU" term="%22Petrovics+G%22">Petrovics G</searchLink>; Uniformed Services University, 4301 Jones Bridge Rd, Bethesda, MD 20814, USA.; Center for Prostate Disease Research, 6720A Rockledge Drive, Suite 300, Bethesda, MD 20817, USA.<br /><searchLink fieldCode="AU" term="%22Parent+MÉ%22">Parent MÉ</searchLink>; Epidemiology and Biostatistics Unit, Centre Armand-Frappier Santé Biotechnologie, Institut national de la recherche scientifique, 531 Boul. des Prairies, Laval, QC, Canada H7V 1B7.; Department of Social and Preventive Medicine, School of Public Health, University of Montreal, Montreal, QC, Canada.<br /><searchLink fieldCode="AU" term="%22Hu+JJ%22">Hu JJ</searchLink>; The University of Miami School of Medicine, Sylvester Comprehensive Cancer Center, 1120 NW 14th Street, CRB 1511, Miami, Florida 33136, USA.<br /><searchLink fieldCode="AU" term="%22Zheng+W%22">Zheng W</searchLink>; Division of Epidemiology, Department of Medicine, Vanderbilt University Medical Center, 2525 West End Avenue, Suite 800, Nashville, TN 37232 USA.<br /><searchLink fieldCode="AU" term="%22Kote-Jarai+Z%22">Kote-Jarai Z</searchLink>; The Institute of Cancer Research, London, SM2 5NG, UK.<br /><searchLink fieldCode="AU" term="%22Eeles+RA%22">Eeles RA</searchLink>; The Institute of Cancer Research, London, SM2 5NG, UK.; Royal Marsden NHS Foundation Trust, London, SW3 6JJ, UK.<br /><searchLink fieldCode="AU" term="%22Maxwell+KN%22">Maxwell KN</searchLink>; Corporal Michael Crescenz Veterans Affairs Medical Center, Philadelphia, PA, USA.; Department of Medicine - Hematology/Oncology, Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Vassy+JL%22">Vassy JL</searchLink>; VA Boston Healthcare System, Boston, MA, USA.; Division of General Internal Medicine and Primary Care, VA Boston Healthcare System, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Seibert+TM%22">Seibert TM</searchLink>; Research Service, VA San Diego Healthcare System, San Diego, CA, USA.; Department of Radiation Medicine and Applied Sciences, University of California San Diego, La Jolla, CA, USA.; Departments of Radiology, University of California San Diego, La Jolla, CA, USA.; Department of Bioengineering, University of California San Diego, La Jolla, CA, USA.; Department of Urology, University of California San Diego, La Jolla, CA, USA.; NORMENT, KG Jebsen Centre, Oslo University Hospital and University of Oslo, Oslo, Norway.
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  Data: <searchLink fieldCode="JN" term="%22101767986%22">MedRxiv : the preprint server for health sciences</searchLink> [medRxiv] 2026 May 13. <i>Date of Electronic Publication: </i>2026 May 13.
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