CPT1A loss promotes lung metastasis in immune-competent mice via a mechanism of mtDNA release and chronic activation of STING pathway.
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| Title: | CPT1A loss promotes lung metastasis in immune-competent mice via a mechanism of mtDNA release and chronic activation of STING pathway. |
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| Authors: | Wang X; Department of Medicine, Division of Rheumatology and Immunology, Vanderbilt Health, Nashville, Tennessee, USA., Chou ST; Program in Cancer Biology, Vanderbilt University, Nashville, Tennessee, USA., Hwang Y; Department of Medicine, Division of Rheumatology and Immunology, Vanderbilt Health, Nashville, Tennessee, USA., Chen J; Department of Medicine, Division of Rheumatology and Immunology, Vanderbilt Health, Nashville, Tennessee, USA.; Program in Cancer Biology, Vanderbilt University, Nashville, Tennessee, USA.; Vanderbilt-Ingram Cancer Center, Nashville, Tennessee, USA.; Vanderbilt Institute for Infection, Immunology, and Inflammation, Nashville, Tennessee, USA.; Department of Cell and Developmental Biology, Vanderbilt University, Nashville, Tennessee, USA.; Veterans Affairs Medical Center, Tennessee Valley Healthcare System, Nashville, Tennessee, USA., Edwards DN; Department of Medicine, Division of Rheumatology and Immunology, Vanderbilt Health, Nashville, Tennessee, USA.; Vanderbilt-Ingram Cancer Center, Nashville, Tennessee, USA. |
| Source: | BioRxiv : the preprint server for biology [bioRxiv] 2026 May 05. Date of Electronic Publication: 2026 May 05. |
| Publication Type: | Journal Article; Preprint |
| Journal Info: | Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 42146389 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: CPT1A loss promotes lung metastasis in immune-competent mice via a mechanism of mtDNA release and chronic activation of STING pathway. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Wang+X%22">Wang X</searchLink>; Department of Medicine, Division of Rheumatology and Immunology, Vanderbilt Health, Nashville, Tennessee, USA.<br /><searchLink fieldCode="AU" term="%22Chou+ST%22">Chou ST</searchLink>; Program in Cancer Biology, Vanderbilt University, Nashville, Tennessee, USA.<br /><searchLink fieldCode="AU" term="%22Hwang+Y%22">Hwang Y</searchLink>; Department of Medicine, Division of Rheumatology and Immunology, Vanderbilt Health, Nashville, Tennessee, USA.<br /><searchLink fieldCode="AU" term="%22Chen+J%22">Chen J</searchLink>; Department of Medicine, Division of Rheumatology and Immunology, Vanderbilt Health, Nashville, Tennessee, USA.; Program in Cancer Biology, Vanderbilt University, Nashville, Tennessee, USA.; Vanderbilt-Ingram Cancer Center, Nashville, Tennessee, USA.; Vanderbilt Institute for Infection, Immunology, and Inflammation, Nashville, Tennessee, USA.; Department of Cell and Developmental Biology, Vanderbilt University, Nashville, Tennessee, USA.; Veterans Affairs Medical Center, Tennessee Valley Healthcare System, Nashville, Tennessee, USA.<br /><searchLink fieldCode="AU" term="%22Edwards+DN%22">Edwards DN</searchLink>; Department of Medicine, Division of Rheumatology and Immunology, Vanderbilt Health, Nashville, Tennessee, USA.; Vanderbilt-Ingram Cancer Center, Nashville, Tennessee, USA. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101680187%22">BioRxiv : the preprint server for biology</searchLink> [bioRxiv] 2026 May 05. <i>Date of Electronic Publication: </i>2026 May 05. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Preprint – Name: TitleSource Label: Journal Info Group: Src Data: <i>Country of Publication: </i>United States <i>NLM ID: </i>101680187 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2692-8205 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2226928205%22">26928205 </searchLink><i>NLM ISO Abbreviation: </i>bioRxiv <i>Subsets: </i>PubMed not MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=42146389 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.64898/2026.05.01.722261 Languages: – Code: eng Text: English Titles: – TitleFull: CPT1A loss promotes lung metastasis in immune-competent mice via a mechanism of mtDNA release and chronic activation of STING pathway. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Wang X – PersonEntity: Name: NameFull: Chou ST – PersonEntity: Name: NameFull: Hwang Y – PersonEntity: Name: NameFull: Chen J – PersonEntity: Name: NameFull: Edwards DN IsPartOfRelationships: – BibEntity: Dates: – D: 05 M: 05 Text: 2026 May 05 Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 2692-8205 Titles: – TitleFull: BioRxiv : the preprint server for biology Type: main |
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