CPT1A loss promotes lung metastasis in immune-competent mice via a mechanism of mtDNA release and chronic activation of STING pathway.
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| Title: | CPT1A loss promotes lung metastasis in immune-competent mice via a mechanism of mtDNA release and chronic activation of STING pathway. |
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| Authors: | Wang X; Department of Medicine, Division of Rheumatology and Immunology, Vanderbilt Health, Nashville, Tennessee, USA., Chou ST; Program in Cancer Biology, Vanderbilt University, Nashville, Tennessee, USA., Hwang Y; Department of Medicine, Division of Rheumatology and Immunology, Vanderbilt Health, Nashville, Tennessee, USA., Chen J; Department of Medicine, Division of Rheumatology and Immunology, Vanderbilt Health, Nashville, Tennessee, USA.; Program in Cancer Biology, Vanderbilt University, Nashville, Tennessee, USA.; Vanderbilt-Ingram Cancer Center, Nashville, Tennessee, USA.; Vanderbilt Institute for Infection, Immunology, and Inflammation, Nashville, Tennessee, USA.; Department of Cell and Developmental Biology, Vanderbilt University, Nashville, Tennessee, USA.; Veterans Affairs Medical Center, Tennessee Valley Healthcare System, Nashville, Tennessee, USA., Edwards DN; Department of Medicine, Division of Rheumatology and Immunology, Vanderbilt Health, Nashville, Tennessee, USA.; Vanderbilt-Ingram Cancer Center, Nashville, Tennessee, USA. |
| Source: | BioRxiv : the preprint server for biology [bioRxiv] 2026 May 05. Date of Electronic Publication: 2026 May 05. |
| Publication Type: | Journal Article; Preprint |
| Journal Info: | Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
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