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Functional remodeling of the parasubthalamic nucleus drives alcohol drinking escalation in dependence.

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Title: Functional remodeling of the parasubthalamic nucleus drives alcohol drinking escalation in dependence.
Authors: Dunning JL; The Scripps Research Institute, Department of Translational Medicine, La Jolla, CA., Kreifeldt M; The Scripps Research Institute, Department of Translational Medicine, La Jolla, CA., Okhuarobo A; The Scripps Research Institute, Department of Translational Medicine, La Jolla, CA., Lopez C; The Scripps Research Institute, Department of Translational Medicine, La Jolla, CA., Varodayan FP; The Scripps Research Institute, Department of Translational Medicine, La Jolla, CA.; Developmental Exposure Alcohol Research Center and Behavioral Neuroscience Program, Department of Psychology, Binghamton University-SUNY, Binghamton, NY., Bajo M; The Scripps Research Institute, Department of Translational Medicine, La Jolla, CA., Smith RJ; Medical University of South Carolina, Charleston, SC.; Department of Psychological and Brain Sciences, Texas A&M University, College Station, TX., Moreau C; The Scripps Research Institute, Department of Translational Medicine, La Jolla, CA., Krull C; The Scripps Research Institute, Department of Translational Medicine, La Jolla, CA., Shu L; The Scripps Research Institute, Department of Translational Medicine, La Jolla, CA., White A; The Scripps Research Institute, Department of Translational Medicine, La Jolla, CA., Macedo G; The Scripps Research Institute, Department of Translational Medicine, La Jolla, CA., Sidhu H; The Scripps Research Institute, Department of Translational Medicine, La Jolla, CA., Becker HC; Medical University of South Carolina, Charleston, SC., Roberto M; The Scripps Research Institute, Department of Translational Medicine, La Jolla, CA., Deisseroth K; Department of Bioengineering, Stanford University, Stanford, CA, USA.; Howard Hughes Medical Institute, Stanford University, Stanford, CA, USA.; Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA, USA., Contet C; The Scripps Research Institute, Department of Translational Medicine, La Jolla, CA.
Source: BioRxiv : the preprint server for biology [bioRxiv] 2026 May 05. Date of Electronic Publication: 2026 May 05.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Functional remodeling of the parasubthalamic nucleus drives alcohol drinking escalation in dependence.
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  Data: <searchLink fieldCode="AU" term="%22Dunning+JL%22">Dunning JL</searchLink>; The Scripps Research Institute, Department of Translational Medicine, La Jolla, CA.<br /><searchLink fieldCode="AU" term="%22Kreifeldt+M%22">Kreifeldt M</searchLink>; The Scripps Research Institute, Department of Translational Medicine, La Jolla, CA.<br /><searchLink fieldCode="AU" term="%22Okhuarobo+A%22">Okhuarobo A</searchLink>; The Scripps Research Institute, Department of Translational Medicine, La Jolla, CA.<br /><searchLink fieldCode="AU" term="%22Lopez+C%22">Lopez C</searchLink>; The Scripps Research Institute, Department of Translational Medicine, La Jolla, CA.<br /><searchLink fieldCode="AU" term="%22Varodayan+FP%22">Varodayan FP</searchLink>; The Scripps Research Institute, Department of Translational Medicine, La Jolla, CA.; Developmental Exposure Alcohol Research Center and Behavioral Neuroscience Program, Department of Psychology, Binghamton University-SUNY, Binghamton, NY.<br /><searchLink fieldCode="AU" term="%22Bajo+M%22">Bajo M</searchLink>; The Scripps Research Institute, Department of Translational Medicine, La Jolla, CA.<br /><searchLink fieldCode="AU" term="%22Smith+RJ%22">Smith RJ</searchLink>; Medical University of South Carolina, Charleston, SC.; Department of Psychological and Brain Sciences, Texas A&M University, College Station, TX.<br /><searchLink fieldCode="AU" term="%22Moreau+C%22">Moreau C</searchLink>; The Scripps Research Institute, Department of Translational Medicine, La Jolla, CA.<br /><searchLink fieldCode="AU" term="%22Krull+C%22">Krull C</searchLink>; The Scripps Research Institute, Department of Translational Medicine, La Jolla, CA.<br /><searchLink fieldCode="AU" term="%22Shu+L%22">Shu L</searchLink>; The Scripps Research Institute, Department of Translational Medicine, La Jolla, CA.<br /><searchLink fieldCode="AU" term="%22White+A%22">White A</searchLink>; The Scripps Research Institute, Department of Translational Medicine, La Jolla, CA.<br /><searchLink fieldCode="AU" term="%22Macedo+G%22">Macedo G</searchLink>; The Scripps Research Institute, Department of Translational Medicine, La Jolla, CA.<br /><searchLink fieldCode="AU" term="%22Sidhu+H%22">Sidhu H</searchLink>; The Scripps Research Institute, Department of Translational Medicine, La Jolla, CA.<br /><searchLink fieldCode="AU" term="%22Becker+HC%22">Becker HC</searchLink>; Medical University of South Carolina, Charleston, SC.<br /><searchLink fieldCode="AU" term="%22Roberto+M%22">Roberto M</searchLink>; The Scripps Research Institute, Department of Translational Medicine, La Jolla, CA.<br /><searchLink fieldCode="AU" term="%22Deisseroth+K%22">Deisseroth K</searchLink>; Department of Bioengineering, Stanford University, Stanford, CA, USA.; Howard Hughes Medical Institute, Stanford University, Stanford, CA, USA.; Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA, USA.<br /><searchLink fieldCode="AU" term="%22Contet+C%22">Contet C</searchLink>; The Scripps Research Institute, Department of Translational Medicine, La Jolla, CA.
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        Value: 10.64898/2026.04.30.722112
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