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Genetic variation in the glymphatic pathway predicts cognition and neurodegeneration in preclinical Alzheimer's disease.

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Title: Genetic variation in the glymphatic pathway predicts cognition and neurodegeneration in preclinical Alzheimer's disease.
Authors: Armstrong AM; Edith Cowan University., O'Brien EK; Edith Cowan University., Fernandez SM; Edith Cowan University., Doré V; Commonwealth Scientific and Industrial Research Organisation., Bourgeat P; Commonwealth Scientific and Industrial Research Organisation., Shishegar R; Commonwealth Scientific and Industrial Research Organisation., Maruff P; Cogstate (Australia)., Rowe CC; Austin Health., Villemagne VL; University of Pittsburgh., Porter T; Edith Cowan University., Laws SM; Edith Cowan University.
Corporate Authors: Alzheimer’s Disease Neuroimaging Initiative, AIBL Research Group
Source: Research square [Res Sq] 2026 May 06. Date of Electronic Publication: 2026 May 06.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101768035 Publication Model: Electronic Cited Medium: Internet ISSN: 2693-5015 (Electronic) Linking ISSN: 26935015 NLM ISO Abbreviation: Res Sq Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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An: 42147167
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PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
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  Data: Genetic variation in the glymphatic pathway predicts cognition and neurodegeneration in preclinical Alzheimer's disease.
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  Data: <searchLink fieldCode="AU" term="%22Armstrong+AM%22">Armstrong AM</searchLink>; Edith Cowan University.<br /><searchLink fieldCode="AU" term="%22O'Brien+EK%22">O'Brien EK</searchLink>; Edith Cowan University.<br /><searchLink fieldCode="AU" term="%22Fernandez+SM%22">Fernandez SM</searchLink>; Edith Cowan University.<br /><searchLink fieldCode="AU" term="%22Doré+V%22">Doré V</searchLink>; Commonwealth Scientific and Industrial Research Organisation.<br /><searchLink fieldCode="AU" term="%22Bourgeat+P%22">Bourgeat P</searchLink>; Commonwealth Scientific and Industrial Research Organisation.<br /><searchLink fieldCode="AU" term="%22Shishegar+R%22">Shishegar R</searchLink>; Commonwealth Scientific and Industrial Research Organisation.<br /><searchLink fieldCode="AU" term="%22Maruff+P%22">Maruff P</searchLink>; Cogstate (Australia).<br /><searchLink fieldCode="AU" term="%22Rowe+CC%22">Rowe CC</searchLink>; Austin Health.<br /><searchLink fieldCode="AU" term="%22Villemagne+VL%22">Villemagne VL</searchLink>; University of Pittsburgh.<br /><searchLink fieldCode="AU" term="%22Porter+T%22">Porter T</searchLink>; Edith Cowan University.<br /><searchLink fieldCode="AU" term="%22Laws+SM%22">Laws SM</searchLink>; Edith Cowan University.
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  Data: <searchLink fieldCode="CA" term="%22Alzheimer%27s+Disease+Neuroimaging+Initiative%22">Alzheimer’s Disease Neuroimaging Initiative</searchLink><br /><searchLink fieldCode="CA" term="%22AIBL+Research+Group%22">AIBL Research Group</searchLink>
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  Data: <searchLink fieldCode="JN" term="%22101768035%22">Research square</searchLink> [Res Sq] 2026 May 06. <i>Date of Electronic Publication: </i>2026 May 06.
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  Data: <i>Country of Publication: </i>United States <i>NLM ID: </i>101768035 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2693-5015 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2226935015%22">26935015 </searchLink><i>NLM ISO Abbreviation: </i>Res Sq <i>Subsets: </i>PubMed not MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=42147167
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      – Type: doi
        Value: 10.21203/rs.3.rs-9444687/v1
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      – Code: eng
        Text: English
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      – TitleFull: Genetic variation in the glymphatic pathway predicts cognition and neurodegeneration in preclinical Alzheimer's disease.
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          Dates:
            – D: 06
              M: 05
              Text: 2026 May 06
              Type: published
              Y: 2026
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