Orchestrating the pre-metastatic niche: roles of stromal mediators and immune cells in metastatic progression and therapeutic targeting.

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Title: Orchestrating the pre-metastatic niche: roles of stromal mediators and immune cells in metastatic progression and therapeutic targeting.
Authors: Zhai Y; Key Laboratory of Tropical Translational Medicine of Ministry of Education & Key Laboratory of Brain Science Research Transformation in Tropical Environment of Hainan Province, School of Basic Medicine and Life Sciences, Hainan Medical University, Haikou, China.; Department of Neurosurgery, The Second Affiliated Hospital of Hainan Medical University, Haikou, China., Peng H; Department of Neurosurgery, Hainan Affiliated Hospital of Hainan Medical University, Hainan, China.; Department of Neurosurgery, Hainan Second People's Hospital, Wuzhishan, China., Liu D; Department of Neurosurgery, The Second Affiliated Hospital of Hainan Medical University, Haikou, China., Huang L; Key Laboratory of Tropical Translational Medicine of Ministry of Education & Key Laboratory of Brain Science Research Transformation in Tropical Environment of Hainan Province, School of Basic Medicine and Life Sciences, Hainan Medical University, Haikou, China., Zhang H; Department of Neurosurgery, The Second Affiliated Hospital of Hainan Medical University, Haikou, China., Jiang H; Department of Neurosurgery, The Second Affiliated Hospital of Hainan Medical University, Haikou, China., Su B; Department of Neurosurgery, The Second Affiliated Hospital of Hainan Medical University, Haikou, China., Zhong Y; Department of Neurosurgery, The Second Affiliated Hospital of Hainan Medical University, Haikou, China., Deng G; Department of Neurosurgery, The Second Affiliated Hospital of Hainan Medical University, Haikou, China., Li N; Department of Neurosurgery, The Second Affiliated Hospital of Hainan Medical University, Haikou, China., Feng J; Department of Neurosurgery, The Second Affiliated Hospital of Hainan Medical University, Haikou, China., Zhang C; Key Laboratory of Tropical Translational Medicine of Ministry of Education & Key Laboratory of Brain Science Research Transformation in Tropical Environment of Hainan Province, School of Basic Medicine and Life Sciences, Hainan Medical University, Haikou, China.
Source: Frontiers in immunology [Front Immunol] 2026 Apr 30; Vol. 17, pp. 1774741. Date of Electronic Publication: 2026 Apr 30 (Print Publication: 2026).
Publication Type: Journal Article; Review
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Orchestrating the pre-metastatic niche: roles of stromal mediators and immune cells in metastatic progression and therapeutic targeting.
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  Data: <searchLink fieldCode="AU" term="%22Zhai+Y%22">Zhai Y</searchLink>; Key Laboratory of Tropical Translational Medicine of Ministry of Education & Key Laboratory of Brain Science Research Transformation in Tropical Environment of Hainan Province, School of Basic Medicine and Life Sciences, Hainan Medical University, Haikou, China.; Department of Neurosurgery, The Second Affiliated Hospital of Hainan Medical University, Haikou, China.<br /><searchLink fieldCode="AU" term="%22Peng+H%22">Peng H</searchLink>; Department of Neurosurgery, Hainan Affiliated Hospital of Hainan Medical University, Hainan, China.; Department of Neurosurgery, Hainan Second People's Hospital, Wuzhishan, China.<br /><searchLink fieldCode="AU" term="%22Liu+D%22">Liu D</searchLink>; Department of Neurosurgery, The Second Affiliated Hospital of Hainan Medical University, Haikou, China.<br /><searchLink fieldCode="AU" term="%22Huang+L%22">Huang L</searchLink>; Key Laboratory of Tropical Translational Medicine of Ministry of Education & Key Laboratory of Brain Science Research Transformation in Tropical Environment of Hainan Province, School of Basic Medicine and Life Sciences, Hainan Medical University, Haikou, China.<br /><searchLink fieldCode="AU" term="%22Zhang+H%22">Zhang H</searchLink>; Department of Neurosurgery, The Second Affiliated Hospital of Hainan Medical University, Haikou, China.<br /><searchLink fieldCode="AU" term="%22Jiang+H%22">Jiang H</searchLink>; Department of Neurosurgery, The Second Affiliated Hospital of Hainan Medical University, Haikou, China.<br /><searchLink fieldCode="AU" term="%22Su+B%22">Su B</searchLink>; Department of Neurosurgery, The Second Affiliated Hospital of Hainan Medical University, Haikou, China.<br /><searchLink fieldCode="AU" term="%22Zhong+Y%22">Zhong Y</searchLink>; Department of Neurosurgery, The Second Affiliated Hospital of Hainan Medical University, Haikou, China.<br /><searchLink fieldCode="AU" term="%22Deng+G%22">Deng G</searchLink>; Department of Neurosurgery, The Second Affiliated Hospital of Hainan Medical University, Haikou, China.<br /><searchLink fieldCode="AU" term="%22Li+N%22">Li N</searchLink>; Department of Neurosurgery, The Second Affiliated Hospital of Hainan Medical University, Haikou, China.<br /><searchLink fieldCode="AU" term="%22Feng+J%22">Feng J</searchLink>; Department of Neurosurgery, The Second Affiliated Hospital of Hainan Medical University, Haikou, China.<br /><searchLink fieldCode="AU" term="%22Zhang+C%22">Zhang C</searchLink>; Key Laboratory of Tropical Translational Medicine of Ministry of Education & Key Laboratory of Brain Science Research Transformation in Tropical Environment of Hainan Province, School of Basic Medicine and Life Sciences, Hainan Medical University, Haikou, China.
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  Data: <searchLink fieldCode="JN" term="%22101560960%22">Frontiers in immunology</searchLink> [Front Immunol] 2026 Apr 30; Vol. 17, pp. 1774741. <i>Date of Electronic Publication: </i>2026 Apr 30 (<i>Print Publication: </i>2026).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Frontiers+Research+Foundation]%22">Frontiers Research Foundation] </searchLink><i>Country of Publication: </i>Switzerland <i>NLM ID: </i>101560960 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Internet <i>ISSN: </i>1664-3224 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2216643224%22">16643224 </searchLink><i>NLM ISO Abbreviation: </i>Front Immunol <i>Subsets: </i>MEDLINE
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        Value: 10.3389/fimmu.2026.1774741
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              Text: 2026 Apr 30
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