Orchestrating the pre-metastatic niche: roles of stromal mediators and immune cells in metastatic progression and therapeutic targeting.

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Title: Orchestrating the pre-metastatic niche: roles of stromal mediators and immune cells in metastatic progression and therapeutic targeting.
Authors: Zhai Y; Key Laboratory of Tropical Translational Medicine of Ministry of Education & Key Laboratory of Brain Science Research Transformation in Tropical Environment of Hainan Province, School of Basic Medicine and Life Sciences, Hainan Medical University, Haikou, China.; Department of Neurosurgery, The Second Affiliated Hospital of Hainan Medical University, Haikou, China., Peng H; Department of Neurosurgery, Hainan Affiliated Hospital of Hainan Medical University, Hainan, China.; Department of Neurosurgery, Hainan Second People's Hospital, Wuzhishan, China., Liu D; Department of Neurosurgery, The Second Affiliated Hospital of Hainan Medical University, Haikou, China., Huang L; Key Laboratory of Tropical Translational Medicine of Ministry of Education & Key Laboratory of Brain Science Research Transformation in Tropical Environment of Hainan Province, School of Basic Medicine and Life Sciences, Hainan Medical University, Haikou, China., Zhang H; Department of Neurosurgery, The Second Affiliated Hospital of Hainan Medical University, Haikou, China., Jiang H; Department of Neurosurgery, The Second Affiliated Hospital of Hainan Medical University, Haikou, China., Su B; Department of Neurosurgery, The Second Affiliated Hospital of Hainan Medical University, Haikou, China., Zhong Y; Department of Neurosurgery, The Second Affiliated Hospital of Hainan Medical University, Haikou, China., Deng G; Department of Neurosurgery, The Second Affiliated Hospital of Hainan Medical University, Haikou, China., Li N; Department of Neurosurgery, The Second Affiliated Hospital of Hainan Medical University, Haikou, China., Feng J; Department of Neurosurgery, The Second Affiliated Hospital of Hainan Medical University, Haikou, China., Zhang C; Key Laboratory of Tropical Translational Medicine of Ministry of Education & Key Laboratory of Brain Science Research Transformation in Tropical Environment of Hainan Province, School of Basic Medicine and Life Sciences, Hainan Medical University, Haikou, China.
Source: Frontiers in immunology [Front Immunol] 2026 Apr 30; Vol. 17, pp. 1774741. Date of Electronic Publication: 2026 Apr 30 (Print Publication: 2026).
Publication Type: Journal Article; Review
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE
Database: MEDLINE Ultimate
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