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Clinical outcomes and predictors of response to PD-(L)1 blockade in patients with NSCLC without actionable genomic alterations who never used tobacco.

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Title: Clinical outcomes and predictors of response to PD-(L)1 blockade in patients with NSCLC without actionable genomic alterations who never used tobacco.
Authors: Gariazzo E; Dana-Farber Cancer Institute Boston, Massachusetts United States., Elkrief A; Memorial Sloan Kettering Cancer Center New York United States., Concannon K; The University of Texas MD Anderson Cancer Center United States., Ognissanti D; University of Perugia Perugia Italy., Dodi A; Ospedale di Parma Parma Italy., Favorito V; Institut Gustave Roussy Villejuif France., Di Federico A; Memorial Sloan Kettering Cancer Center New York United States., De Giglio A; Policlinico S.Orsola-Malpighi Bologna Italy., Brunetti L; Imperial College London London United Kingdom., Santo V; Dana-Farber Cancer Institute Boston United States., Pecci F; Dana-Farber Cancer Institute Boston, Massachusetts United States., Aldea M; Institut Gustave Roussy Villejuif, Massachusetts France., Garbo E; Dana-Farber Cancer Institute Boston, Massachusetts United States., Alessi JV; Dana-Farber Cancer Institute Boston, MA United States., LoPiccolo J; Dana-Farber Cancer Institute Boston United States., Paoloni F; Dana-Farber Cancer Institute Boston, MA United States., Nishino M; Dana-Farber/Brigham and Women's Cancer Center Boston, MA United States., Sholl LM; Brigham and Women's Hospital Boston, MA United States., Florez N; Dana-Farber Cancer Institute United States., Rotow J; Dana-Farber Cancer Institute Boston, MA United States., Frumm SM; Dana-Farber Cancer Institute Boston, MA United States., Hong L; The University of Texas MD Anderson Cancer Center Houston, TX United States., Zhang J; The University of Texas MD Anderson Cancer Center Houston, TX United States., Gibbons D; The University of Texas MD Anderson Cancer Center Houston, TX United States., Wang X; Harvard University Boston, MA United States., Landi L; Istituti Fisioterapici Ospitalieri Italy., Cipriani L; Instituto Nazionale Tumori Regina Elena Rome, RM Italy., Rakaee M; Brigham and Women's Hospital Boston United States., Cortellini A; Università Campus Bio-Medico Rome Italy., Tiseo M; Ospedale di Parma Parma Italy., Cappuzzo F; Instituto Nazionale Tumori Regina Elena Rome Italy., Ardizzoni A; University of Bologna Bologna Italy., Awad MM; Dana-Farber Cancer Institute Boston, Massachusetts United States., Heymach JV; The University of Texas MD Anderson Cancer Center Houston, TX United States., Scalera S; Instituto Nazionale Tumori Regina Elena Rome Italy., Maugeri-Saccà M; Instituto Nazionale Tumori Regina Elena Rome Italy., Metro G; University of Perugia Perugia Italy., Vokes N; The University of Texas MD Anderson Cancer Center Houston, TX United States., Schoenfeld A; Memorial Sloan Kettering Cancer Center New York, NY United States., Ricciuti B; Dana-Farber/Harvard Cancer Center Boston, Massachusetts United States.
Source: Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2026 May 18. Date of Electronic Publication: 2026 May 18.
Publication Type: Journal Article
Journal Info: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 9502500 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1557-3265 (Electronic) Linking ISSN: 10780432 NLM ISO Abbreviation: Clin Cancer Res Subsets: MEDLINE
Database: MEDLINE Ultimate
FullText Text:
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  Data: Clinical outcomes and predictors of response to PD-(L)1 blockade in patients with NSCLC without actionable genomic alterations who never used tobacco.
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  Data: <searchLink fieldCode="AU" term="%22Gariazzo+E%22">Gariazzo E</searchLink>; Dana-Farber Cancer Institute Boston, Massachusetts United States.<br /><searchLink fieldCode="AU" term="%22Elkrief+A%22">Elkrief A</searchLink>; Memorial Sloan Kettering Cancer Center New York United States.<br /><searchLink fieldCode="AU" term="%22Concannon+K%22">Concannon K</searchLink>; The University of Texas MD Anderson Cancer Center United States.<br /><searchLink fieldCode="AU" term="%22Ognissanti+D%22">Ognissanti D</searchLink>; University of Perugia Perugia Italy.<br /><searchLink fieldCode="AU" term="%22Dodi+A%22">Dodi A</searchLink>; Ospedale di Parma Parma Italy.<br /><searchLink fieldCode="AU" term="%22Favorito+V%22">Favorito V</searchLink>; Institut Gustave Roussy Villejuif France.<br /><searchLink fieldCode="AU" term="%22Di+Federico+A%22">Di Federico A</searchLink>; Memorial Sloan Kettering Cancer Center New York United States.<br /><searchLink fieldCode="AU" term="%22De+Giglio+A%22">De Giglio A</searchLink>; Policlinico S.Orsola-Malpighi Bologna Italy.<br /><searchLink fieldCode="AU" term="%22Brunetti+L%22">Brunetti L</searchLink>; Imperial College London London United Kingdom.<br /><searchLink fieldCode="AU" term="%22Santo+V%22">Santo V</searchLink>; Dana-Farber Cancer Institute Boston United States.<br /><searchLink fieldCode="AU" term="%22Pecci+F%22">Pecci F</searchLink>; Dana-Farber Cancer Institute Boston, Massachusetts United States.<br /><searchLink fieldCode="AU" term="%22Aldea+M%22">Aldea M</searchLink>; Institut Gustave Roussy Villejuif, Massachusetts France.<br /><searchLink fieldCode="AU" term="%22Garbo+E%22">Garbo E</searchLink>; Dana-Farber Cancer Institute Boston, Massachusetts United States.<br /><searchLink fieldCode="AU" term="%22Alessi+JV%22">Alessi JV</searchLink>; Dana-Farber Cancer Institute Boston, MA United States.<br /><searchLink fieldCode="AU" term="%22LoPiccolo+J%22">LoPiccolo J</searchLink>; Dana-Farber Cancer Institute Boston United States.<br /><searchLink fieldCode="AU" term="%22Paoloni+F%22">Paoloni F</searchLink>; Dana-Farber Cancer Institute Boston, MA United States.<br /><searchLink fieldCode="AU" term="%22Nishino+M%22">Nishino M</searchLink>; Dana-Farber/Brigham and Women's Cancer Center Boston, MA United States.<br /><searchLink fieldCode="AU" term="%22Sholl+LM%22">Sholl LM</searchLink>; Brigham and Women's Hospital Boston, MA United States.<br /><searchLink fieldCode="AU" term="%22Florez+N%22">Florez N</searchLink>; Dana-Farber Cancer Institute United States.<br /><searchLink fieldCode="AU" term="%22Rotow+J%22">Rotow J</searchLink>; Dana-Farber Cancer Institute Boston, MA United States.<br /><searchLink fieldCode="AU" term="%22Frumm+SM%22">Frumm SM</searchLink>; Dana-Farber Cancer Institute Boston, MA United States.<br /><searchLink fieldCode="AU" term="%22Hong+L%22">Hong L</searchLink>; The University of Texas MD Anderson Cancer Center Houston, TX United States.<br /><searchLink fieldCode="AU" term="%22Zhang+J%22">Zhang J</searchLink>; The University of Texas MD Anderson Cancer Center Houston, TX United States.<br /><searchLink fieldCode="AU" term="%22Gibbons+D%22">Gibbons D</searchLink>; The University of Texas MD Anderson Cancer Center Houston, TX United States.<br /><searchLink fieldCode="AU" term="%22Wang+X%22">Wang X</searchLink>; Harvard University Boston, MA United States.<br /><searchLink fieldCode="AU" term="%22Landi+L%22">Landi L</searchLink>; Istituti Fisioterapici Ospitalieri Italy.<br /><searchLink fieldCode="AU" term="%22Cipriani+L%22">Cipriani L</searchLink>; Instituto Nazionale Tumori Regina Elena Rome, RM Italy.<br /><searchLink fieldCode="AU" term="%22Rakaee+M%22">Rakaee M</searchLink>; Brigham and Women's Hospital Boston United States.<br /><searchLink fieldCode="AU" term="%22Cortellini+A%22">Cortellini A</searchLink>; Università Campus Bio-Medico Rome Italy.<br /><searchLink fieldCode="AU" term="%22Tiseo+M%22">Tiseo M</searchLink>; Ospedale di Parma Parma Italy.<br /><searchLink fieldCode="AU" term="%22Cappuzzo+F%22">Cappuzzo F</searchLink>; Instituto Nazionale Tumori Regina Elena Rome Italy.<br /><searchLink fieldCode="AU" term="%22Ardizzoni+A%22">Ardizzoni A</searchLink>; University of Bologna Bologna Italy.<br /><searchLink fieldCode="AU" term="%22Awad+MM%22">Awad MM</searchLink>; Dana-Farber Cancer Institute Boston, Massachusetts United States.<br /><searchLink fieldCode="AU" term="%22Heymach+JV%22">Heymach JV</searchLink>; The University of Texas MD Anderson Cancer Center Houston, TX United States.<br /><searchLink fieldCode="AU" term="%22Scalera+S%22">Scalera S</searchLink>; Instituto Nazionale Tumori Regina Elena Rome Italy.<br /><searchLink fieldCode="AU" term="%22Maugeri-Saccà+M%22">Maugeri-Saccà M</searchLink>; Instituto Nazionale Tumori Regina Elena Rome Italy.<br /><searchLink fieldCode="AU" term="%22Metro+G%22">Metro G</searchLink>; University of Perugia Perugia Italy.<br /><searchLink fieldCode="AU" term="%22Vokes+N%22">Vokes N</searchLink>; The University of Texas MD Anderson Cancer Center Houston, TX United States.<br /><searchLink fieldCode="AU" term="%22Schoenfeld+A%22">Schoenfeld A</searchLink>; Memorial Sloan Kettering Cancer Center New York, NY United States.<br /><searchLink fieldCode="AU" term="%22Ricciuti+B%22">Ricciuti B</searchLink>; Dana-Farber/Harvard Cancer Center Boston, Massachusetts United States.
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