The FICUS cluster randomized controlled trial of a family support intervention in adult intensive care units: mental health and family functioning outcomes.

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Title: The FICUS cluster randomized controlled trial of a family support intervention in adult intensive care units: mental health and family functioning outcomes.
Authors: Riguzzi M; Faculty of Medicine, Institute for Implementation Science in Health Care, University of Zurich, Zurich, Switzerland.; Centre for Clinical Nursing Science, University Hospital Zurich, Zurich, Switzerland., Jeitziner MM; Department of Intensive Care Medicine, Inselspital, Bern University Hospital, Bern, Switzerland., Rufer M; Center for Psychiatry and Psychotherapy, Clinic Zugersee, Oberwil‑Zug, Switzerland.; Department of Psychiatry, Psychotherapy, and Psychosomatics, Psychiatric University Hospital Zurich, University of Zurich, Zurich, Switzerland., von Felten S; Department of Biostatistics at Epidemiology, Biostatistics and Prevention Institute, University of Zurich, Zurich, Switzerland., Verweij L; Faculty of Medicine, Institute for Implementation Science in Health Care, University of Zurich, Zurich, Switzerland.; Centre for Clinical Nursing Science, University Hospital Zurich, Zurich, Switzerland., Oesch S; Faculty of Medicine, Institute for Implementation Science in Health Care, University of Zurich, Zurich, Switzerland.; Centre for Clinical Nursing Science, University Hospital Zurich, Zurich, Switzerland., Sutter S; Faculty of Medicine, Institute for Implementation Science in Health Care, University of Zurich, Zurich, Switzerland.; Centre for Clinical Nursing Science, University Hospital Zurich, Zurich, Switzerland., Safford J; Patient Research Partner, Bern, Switzerland., Wenzler MS; Institute for Anesthesia and Intensive Care Medicine, Hirslanden Clinic Zurich, Zurich, Switzerland., Welter J; Institute for Anesthesia, Spital Thurgau Frauenfeld, Frauenfeld, Switzerland., Wiegand J; Intensive Care Unit, Lindenhofgruppe, Lindenhofspital, Bern, Switzerland., Wiechmann D; Center of Intensive Care Medicine, Cantonal Hospital Winterthur, Winterthur, Switzerland., von Dach C; Department of Nursing, Solothurn Hospitals AG, Solothurn, Switzerland., Steiger P; Institute of Intensive Care Medicine, University Hospital Zurich, University of Zurich, Zurich, Switzerland., Siegrist E; Institute of Intensive Care Medicine, University Hospital Zurich, Zurich, Switzerland., Ruch N; Department of Intensive Care Medicine, Inselspital, Bern University Hospital, Bern, Switzerland., Pietsch U; Division of Perioperative Intensive Care Medicine, Kantonsspital St.Gallen, St. Gallen, Switzerland., Moser M; Interdisciplinary Intensive Care Unit, Department of Perioperative Medicine, Solothurn Hospitals AG, Cantonal Hospital Olten, Olten, Switzerland., Massarotto P; Institute of Intensive Care Medicine, University Hospital Zurich, Zurich, Switzerland., Lussmann F; Center of Intensive Care Medicine, Lucerne Cantonal Hospital, Lucerne, Switzerland., Keller Y; Nurse Development Department, Cantonal Hospital Baden, Baden, Switzerland., Hoffmann JE; Nursing Development and Quality Unit, Lucerne Cantonal Hospital, Lucerne, Switzerland., Hertler B; Institute of Intensive Care Medicine, University Hospital Zurich, University of Zurich, Zurich, Switzerland., Heise A; Intensive Care Unit, Hospital of Thun, Thun, Switzerland., Dullenkopf A; Institute for Anesthesia, Spital Thurgau Frauenfeld, Frauenfeld, Switzerland., Burkhalter H; Department of Nursing and Specialist Support, Nursing Development, Cantonal Hospital Graubünden, Chur, Switzerland., Bühler PK; Center of Intensive Care Medicine, Cantonal Hospital Winterthur, Winterthur, Switzerland., Brunner C; Division of Perioperative Intensive Care Medicine, Kantonsspital St.Gallen, St. Gallen, Switzerland., Brülhart D; Department of Biostatistics at Epidemiology, Biostatistics and Prevention Institute, University of Zurich, Zurich, Switzerland., Betschart U; Department of Intensive Care Medicine, Kantonsspital St.Gallen, St. Gallen, Switzerland., Bergmann-Kipfer B; Intensive Care Unit, Hospital of Thun, Thun, Switzerland., Filipovic M; Division of Perioperative Intensive Care Medicine, Kantonsspital St.Gallen, St. Gallen, Switzerland., Naef R; Faculty of Medicine, Institute for Implementation Science in Health Care, University of Zurich, Zurich, Switzerland. rahel.naef@usz.ch.; Centre for Clinical Nursing Science, University Hospital Zurich, Zurich, Switzerland. rahel.naef@usz.ch.
Corporate Authors: FICUS study group
Source: Intensive care medicine [Intensive Care Med] 2026 Apr; Vol. 52 (4), pp. 637-650. Date of Electronic Publication: 2026 May 18.
Publication Type: Journal Article; Randomized Controlled Trial
Journal Info: Publisher: Springer Verlag Country of Publication: United States NLM ID: 7704851 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-1238 (Electronic) Linking ISSN: 03424642 NLM ISO Abbreviation: Intensive Care Med Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Riguzzi+M%22">Riguzzi M</searchLink>; Faculty of Medicine, Institute for Implementation Science in Health Care, University of Zurich, Zurich, Switzerland.; Centre for Clinical Nursing Science, University Hospital Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Jeitziner+MM%22">Jeitziner MM</searchLink>; Department of Intensive Care Medicine, Inselspital, Bern University Hospital, Bern, Switzerland.<br /><searchLink fieldCode="AU" term="%22Rufer+M%22">Rufer M</searchLink>; Center for Psychiatry and Psychotherapy, Clinic Zugersee, Oberwil‑Zug, Switzerland.; Department of Psychiatry, Psychotherapy, and Psychosomatics, Psychiatric University Hospital Zurich, University of Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22von+Felten+S%22">von Felten S</searchLink>; Department of Biostatistics at Epidemiology, Biostatistics and Prevention Institute, University of Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Verweij+L%22">Verweij L</searchLink>; Faculty of Medicine, Institute for Implementation Science in Health Care, University of Zurich, Zurich, Switzerland.; Centre for Clinical Nursing Science, University Hospital Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Oesch+S%22">Oesch S</searchLink>; Faculty of Medicine, Institute for Implementation Science in Health Care, University of Zurich, Zurich, Switzerland.; Centre for Clinical Nursing Science, University Hospital Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Sutter+S%22">Sutter S</searchLink>; Faculty of Medicine, Institute for Implementation Science in Health Care, University of Zurich, Zurich, Switzerland.; Centre for Clinical Nursing Science, University Hospital Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Safford+J%22">Safford J</searchLink>; Patient Research Partner, Bern, Switzerland.<br /><searchLink fieldCode="AU" term="%22Wenzler+MS%22">Wenzler MS</searchLink>; Institute for Anesthesia and Intensive Care Medicine, Hirslanden Clinic Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Welter+J%22">Welter J</searchLink>; Institute for Anesthesia, Spital Thurgau Frauenfeld, Frauenfeld, Switzerland.<br /><searchLink fieldCode="AU" term="%22Wiegand+J%22">Wiegand J</searchLink>; Intensive Care Unit, Lindenhofgruppe, Lindenhofspital, Bern, Switzerland.<br /><searchLink fieldCode="AU" term="%22Wiechmann+D%22">Wiechmann D</searchLink>; Center of Intensive Care Medicine, Cantonal Hospital Winterthur, Winterthur, Switzerland.<br /><searchLink fieldCode="AU" term="%22von+Dach+C%22">von Dach C</searchLink>; Department of Nursing, Solothurn Hospitals AG, Solothurn, Switzerland.<br /><searchLink fieldCode="AU" term="%22Steiger+P%22">Steiger P</searchLink>; Institute of Intensive Care Medicine, University Hospital Zurich, University of Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Siegrist+E%22">Siegrist E</searchLink>; Institute of Intensive Care Medicine, University Hospital Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Ruch+N%22">Ruch N</searchLink>; Department of Intensive Care Medicine, Inselspital, Bern University Hospital, Bern, Switzerland.<br /><searchLink fieldCode="AU" term="%22Pietsch+U%22">Pietsch U</searchLink>; Division of Perioperative Intensive Care Medicine, Kantonsspital St.Gallen, St. Gallen, Switzerland.<br /><searchLink fieldCode="AU" term="%22Moser+M%22">Moser M</searchLink>; Interdisciplinary Intensive Care Unit, Department of Perioperative Medicine, Solothurn Hospitals AG, Cantonal Hospital Olten, Olten, Switzerland.<br /><searchLink fieldCode="AU" term="%22Massarotto+P%22">Massarotto P</searchLink>; Institute of Intensive Care Medicine, University Hospital Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Lussmann+F%22">Lussmann F</searchLink>; Center of Intensive Care Medicine, Lucerne Cantonal Hospital, Lucerne, Switzerland.<br /><searchLink fieldCode="AU" term="%22Keller+Y%22">Keller Y</searchLink>; Nurse Development Department, Cantonal Hospital Baden, Baden, Switzerland.<br /><searchLink fieldCode="AU" term="%22Hoffmann+JE%22">Hoffmann JE</searchLink>; Nursing Development and Quality Unit, Lucerne Cantonal Hospital, Lucerne, Switzerland.<br /><searchLink fieldCode="AU" term="%22Hertler+B%22">Hertler B</searchLink>; Institute of Intensive Care Medicine, University Hospital Zurich, University of Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Heise+A%22">Heise A</searchLink>; Intensive Care Unit, Hospital of Thun, Thun, Switzerland.<br /><searchLink fieldCode="AU" term="%22Dullenkopf+A%22">Dullenkopf A</searchLink>; Institute for Anesthesia, Spital Thurgau Frauenfeld, Frauenfeld, Switzerland.<br /><searchLink fieldCode="AU" term="%22Burkhalter+H%22">Burkhalter H</searchLink>; Department of Nursing and Specialist Support, Nursing Development, Cantonal Hospital Graubünden, Chur, Switzerland.<br /><searchLink fieldCode="AU" term="%22Bühler+PK%22">Bühler PK</searchLink>; Center of Intensive Care Medicine, Cantonal Hospital Winterthur, Winterthur, Switzerland.<br /><searchLink fieldCode="AU" term="%22Brunner+C%22">Brunner C</searchLink>; Division of Perioperative Intensive Care Medicine, Kantonsspital St.Gallen, St. Gallen, Switzerland.<br /><searchLink fieldCode="AU" term="%22Brülhart+D%22">Brülhart D</searchLink>; Department of Biostatistics at Epidemiology, Biostatistics and Prevention Institute, University of Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Betschart+U%22">Betschart U</searchLink>; Department of Intensive Care Medicine, Kantonsspital St.Gallen, St. Gallen, Switzerland.<br /><searchLink fieldCode="AU" term="%22Bergmann-Kipfer+B%22">Bergmann-Kipfer B</searchLink>; Intensive Care Unit, Hospital of Thun, Thun, Switzerland.<br /><searchLink fieldCode="AU" term="%22Filipovic+M%22">Filipovic M</searchLink>; Division of Perioperative Intensive Care Medicine, Kantonsspital St.Gallen, St. Gallen, Switzerland.<br /><searchLink fieldCode="AU" term="%22Naef+R%22">Naef R</searchLink>; Faculty of Medicine, Institute for Implementation Science in Health Care, University of Zurich, Zurich, Switzerland. rahel.naef@usz.ch.; Centre for Clinical Nursing Science, University Hospital Zurich, Zurich, Switzerland. rahel.naef@usz.ch.
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