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Efficient gram-scale synthesis and preclinical evaluation of an escin-derived therapeutic for ovarian cancer.

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Title: Efficient gram-scale synthesis and preclinical evaluation of an escin-derived therapeutic for ovarian cancer.
Authors: Wong CL; Evaeon (HK) Life Technology Limited, Hong Kong., Au TYK; Evaeon (HK) Life Technology Limited, Hong Kong., Chan CS; Evaeon (HK) Life Technology Limited, Hong Kong. Electronic address: chishingchan@evaeon.com.
Source: Bioorganic & medicinal chemistry [Bioorg Med Chem] 2026 Aug; Vol. 139, pp. 118705. Date of Electronic Publication: 2026 May 13.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Science Country of Publication: England NLM ID: 9413298 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1464-3391 (Electronic) Linking ISSN: 09680896 NLM ISO Abbreviation: Bioorg Med Chem Subsets: MEDLINE
Database: MEDLINE Ultimate
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Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 42150269
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
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  Data: Efficient gram-scale synthesis and preclinical evaluation of an escin-derived therapeutic for ovarian cancer.
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  Data: <searchLink fieldCode="AU" term="%22Wong+CL%22">Wong CL</searchLink>; Evaeon (HK) Life Technology Limited, Hong Kong.<br /><searchLink fieldCode="AU" term="%22Au+TYK%22">Au TYK</searchLink>; Evaeon (HK) Life Technology Limited, Hong Kong.<br /><searchLink fieldCode="AU" term="%22Chan+CS%22">Chan CS</searchLink>; Evaeon (HK) Life Technology Limited, Hong Kong. Electronic address: chishingchan@evaeon.com.
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  Data: <searchLink fieldCode="JN" term="%229413298%22">Bioorganic & medicinal chemistry</searchLink> [Bioorg Med Chem] 2026 Aug; Vol. 139, pp. 118705. <i>Date of Electronic Publication: </i>2026 May 13.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier+Science%22">Elsevier Science </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>9413298 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1464-3391 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2209680896%22">09680896 </searchLink><i>NLM ISO Abbreviation: </i>Bioorg Med Chem <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=42150269
RecordInfo BibRecord:
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      – Type: doi
        Value: 10.1016/j.bmc.2026.118705
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      – Code: eng
        Text: English
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      Pagination:
        StartPage: 118705
    Titles:
      – TitleFull: Efficient gram-scale synthesis and preclinical evaluation of an escin-derived therapeutic for ovarian cancer.
        Type: main
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          Name:
            NameFull: Wong CL
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            NameFull: Au TYK
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            NameFull: Chan CS
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          Dates:
            – D: 01
              M: 08
              Text: 2026 Aug
              Type: published
              Y: 2026
          Identifiers:
            – Type: issn-electronic
              Value: 1464-3391
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            – Type: volume
              Value: 139
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            – TitleFull: Bioorganic & medicinal chemistry
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