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Comparison of iloprost therapy versus non-iloprost therapy for severe frostbite: a retrospective cohort study of two Canadian cities.

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Title: Comparison of iloprost therapy versus non-iloprost therapy for severe frostbite: a retrospective cohort study of two Canadian cities.
Authors: O'Dochartaigh D; Emergency, Alberta Health Services, Edmonton, Alberta, Canada.; Clinical Operations/Research, Shock Trauma Air Rescue Society, Edmonton, Alberta, Canada.; Department of Emergency Medicine, Faculty of Medicine and Dendistry, University of Alberta, Edmonton, Alberta, Canada., Douma MJ; University College Dublin, Dublin, Leinster, Ireland matthew.douma@ucdconnect.ie douma@ualberta.ca.; Department of Critical Care, University of Alberta, Edmonton, Alberta, Canada., Picard C; Nursing, University of Alberta, Edmonton, Alberta, Canada., Violato E; University of Alberta, Edmonton, Alberta, Canada., Poole A; Surgery, University of Calgary Faculty of Medicine, Calgary, Alberta, Canada., Gauthier J; Whitehorse General Hospital, Whitehorse, Yukon, Canada., Armour A; University of Alberta Faculty of Medicine & Dentistry, Edmonton, Alberta, Canada., Tiwana D; Kinesiology, University of Alberta, Edmonton, Alberta, Canada., Harrigan T; School of Nursing, University of Calgary, Calgary, Alberta, Canada.; Medicine, Alberta Health Services, Edmonton, Alberta, Canada., Gabriel V; Clinical Neurosciences and Surgery, University of Calgary Faculty of Medicine, Calgary, Alberta, Canada., Brown J; Departments of Clinical Neurosciences and Surgery, University of Calgary Cumming School of Medicine, Calgary, Alberta, Canada., Ghosh SM; Department of Medicine and Psychiatry, University of Calgary, Calgary, Alberta, Canada.; Department of General Internal Medicine and Neurology, University of Alberta, Edmonton, Alberta, Canada., MacNairn I; University of Alberta Faculty of Medicine & Dentistry, Edmonton, Alberta, Canada., Khangura J; Department of Emergency Medicine, Faculty of Medicine and Dendistry, University of Alberta, Edmonton, Alberta, Canada., Boucher H; Alberta Health Services, Calgary, Alberta, Canada., Robinson L; University of Alberta, Edmonton, Alberta, Canada., Watt L; Emergency, Alberta Health Services, Edmonton, Alberta, Canada., Van Nest J; Public Health, Primary Care Alberta, Edmonton, Alberta, Canada., Bown JL; University of Alberta, Edmonton, Alberta, Canada., Mageau A; Alberta Health Services, Calgary, Alberta, Canada., Crooks S; Department of Emergency Medicine, University of Calgary, Calgary, Alberta, Canada., Efegoma Y; University of Alberta Faculty of Medicine & Dentistry, Edmonton, Alberta, Canada., Byrnes K; University of Alberta Faculty of Medicine & Dentistry, Edmonton, Alberta, Canada., Middleton S; Royal Alexandra Hospital, Alberta Health Services, Edmonton, Alberta, Canada., Hayward J; Department of Emergency Medicine, Faculty of Medicine and Dendistry, University of Alberta, Edmonton, Alberta, Canada., Whiteside B; Department of Emergency Medicine, Faculty of Medicine and Dendistry, University of Alberta, Edmonton, Alberta, Canada., Dong K; Department of Emergency Medicine, Faculty of Medicine and Dendistry, University of Alberta, Edmonton, Alberta, Canada.; Inner City Health and Wellness Program, Royal Alexandra Hospital, Edmonton, Alberta, Canada., Hyshka E; Inner City Health and Wellness Program, Royal Alexandra Hospital, Edmonton, Alberta, Canada.; School of Public Health, University of Alberta, Edmonton, Alberta, Canada., Zakhary M; University of Alberta Faculty of Medicine & Dentistry, Edmonton, Alberta, Canada., Maclean S; Department of Emergency Medicine, Faculty of Medicine and Dendistry, University of Alberta, Edmonton, Alberta, Canada.
Source: BMJ open [BMJ Open] 2026 May 18; Vol. 16 (5), pp. e110475. Date of Electronic Publication: 2026 May 18.
Publication Type: Journal Article; Comparative Study
Journal Info: Publisher: BMJ Publishing Group Ltd Country of Publication: England NLM ID: 101552874 Publication Model: Electronic Cited Medium: Internet ISSN: 2044-6055 (Electronic) Linking ISSN: 20446055 NLM ISO Abbreviation: BMJ Open Subsets: MEDLINE
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  Data: Comparison of iloprost therapy versus non-iloprost therapy for severe frostbite: a retrospective cohort study of two Canadian cities.
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Whitehorse General Hospital, Whitehorse, Yukon, Canada.<br /><searchLink fieldCode="AU" term="%22Armour+A%22">Armour A</searchLink>; University of Alberta Faculty of Medicine & Dentistry, Edmonton, Alberta, Canada.<br /><searchLink fieldCode="AU" term="%22Tiwana+D%22">Tiwana D</searchLink>; Kinesiology, University of Alberta, Edmonton, Alberta, Canada.<br /><searchLink fieldCode="AU" term="%22Harrigan+T%22">Harrigan T</searchLink>; School of Nursing, University of Calgary, Calgary, Alberta, Canada.; Medicine, Alberta Health Services, Edmonton, Alberta, Canada.<br /><searchLink fieldCode="AU" term="%22Gabriel+V%22">Gabriel V</searchLink>; Clinical Neurosciences and Surgery, University of Calgary Faculty of Medicine, Calgary, Alberta, Canada.<br /><searchLink fieldCode="AU" term="%22Brown+J%22">Brown J</searchLink>; Departments of Clinical Neurosciences and Surgery, University of Calgary Cumming School of Medicine, Calgary, Alberta, Canada.<br /><searchLink fieldCode="AU" term="%22Ghosh+SM%22">Ghosh SM</searchLink>; Department of Medicine and Psychiatry, University of Calgary, Calgary, Alberta, Canada.; Department of General Internal Medicine and Neurology, University of Alberta, Edmonton, Alberta, Canada.<br /><searchLink fieldCode="AU" term="%22MacNairn+I%22">MacNairn I</searchLink>; University of Alberta Faculty of Medicine & Dentistry, Edmonton, Alberta, Canada.<br /><searchLink fieldCode="AU" term="%22Khangura+J%22">Khangura J</searchLink>; Department of Emergency Medicine, Faculty of Medicine and Dendistry, University of Alberta, Edmonton, Alberta, Canada.<br /><searchLink fieldCode="AU" term="%22Boucher+H%22">Boucher H</searchLink>; Alberta Health Services, Calgary, Alberta, Canada.<br /><searchLink fieldCode="AU" term="%22Robinson+L%22">Robinson L</searchLink>; University of Alberta, Edmonton, Alberta, Canada.<br /><searchLink fieldCode="AU" term="%22Watt+L%22">Watt L</searchLink>; Emergency, Alberta Health Services, Edmonton, Alberta, Canada.<br /><searchLink fieldCode="AU" term="%22Van+Nest+J%22">Van Nest J</searchLink>; 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Department of Emergency Medicine, Faculty of Medicine and Dendistry, University of Alberta, Edmonton, Alberta, Canada.<br /><searchLink fieldCode="AU" term="%22Whiteside+B%22">Whiteside B</searchLink>; Department of Emergency Medicine, Faculty of Medicine and Dendistry, University of Alberta, Edmonton, Alberta, Canada.<br /><searchLink fieldCode="AU" term="%22Dong+K%22">Dong K</searchLink>; Department of Emergency Medicine, Faculty of Medicine and Dendistry, University of Alberta, Edmonton, Alberta, Canada.; Inner City Health and Wellness Program, Royal Alexandra Hospital, Edmonton, Alberta, Canada.<br /><searchLink fieldCode="AU" term="%22Hyshka+E%22">Hyshka E</searchLink>; Inner City Health and Wellness Program, Royal Alexandra Hospital, Edmonton, Alberta, Canada.; School of Public Health, University of Alberta, Edmonton, Alberta, Canada.<br /><searchLink fieldCode="AU" term="%22Zakhary+M%22">Zakhary M</searchLink>; University of Alberta Faculty of Medicine & Dentistry, Edmonton, Alberta, Canada.<br /><searchLink fieldCode="AU" term="%22Maclean+S%22">Maclean S</searchLink>; Department of Emergency Medicine, Faculty of Medicine and Dendistry, University of Alberta, Edmonton, Alberta, Canada.
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  Data: <searchLink fieldCode="JN" term="%22101552874%22">BMJ open</searchLink> [BMJ Open] 2026 May 18; Vol. 16 (5), pp. e110475. <i>Date of Electronic Publication: </i>2026 May 18.
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