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Distinct roles of MCM2-7 subunits in replication licensing in human cells.

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Title: Distinct roles of MCM2-7 subunits in replication licensing in human cells.
Authors: Fan X; Division of Life Science, The Hong Kong University of Science and Technology, Hong Kong, China.; School of Biological Sciences, The University of Hong Kong, Hong Kong, China., Lam WH; Division of Life Science, The Hong Kong University of Science and Technology, Hong Kong, China., Yu D; Division of Life Science, The Hong Kong University of Science and Technology, Hong Kong, China., Jiang H; Division of Life Science, The Hong Kong University of Science and Technology, Hong Kong, China., Hui YC; Division of Life Science, The Hong Kong University of Science and Technology, Hong Kong, China.; School of Biological Sciences, The University of Hong Kong, Hong Kong, China., Zhang Q; Division of Life Science, The Hong Kong University of Science and Technology, Hong Kong, China.; School of Biological Sciences, The University of Hong Kong, Hong Kong, China., Li W; The First Clinical College, Henan Medical University, Xinxiang, Henan, China., Li J; School of Biological Sciences, The University of Hong Kong, Hong Kong, China., Lin Z; School of Biological Sciences, The University of Hong Kong, Hong Kong, China., Yin Z; Division of Life Science, The Hong Kong University of Science and Technology, Hong Kong, China., Wu W; School of Biological Sciences, The University of Hong Kong, Hong Kong, China., Zhang Y; Biological Cryo-EM Center, The Hong Kong University of Science and Technology, Hong Kong, China., Liu N; School of Biological Sciences, The University of Hong Kong, Hong Kong, China., Kanemaki MT; National Institute of Genetics, Research Organization of Information and Systems (ROIS), Shizuoka, Japan.; Graduate Institute for Advanced Studies, SOKENDAI, Shizuoka, Japan.; Department of Biological Science, Graduate School of Science, The University of Tokyo, Tokyo, Japan., Dang S; Division of Life Science, The Hong Kong University of Science and Technology, Hong Kong, China., Zhai Y; Division of Life Science, The Hong Kong University of Science and Technology, Hong Kong, China. zhai@ust.hk.
Source: Nature communications [Nat Commun] 2026 May 14; Vol. 17 (1). Date of Electronic Publication: 2026 May 14.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Fan+X%22">Fan X</searchLink>; Division of Life Science, The Hong Kong University of Science and Technology, Hong Kong, China.; School of Biological Sciences, The University of Hong Kong, Hong Kong, China.<br /><searchLink fieldCode="AU" term="%22Lam+WH%22">Lam WH</searchLink>; Division of Life Science, The Hong Kong University of Science and Technology, Hong Kong, China.<br /><searchLink fieldCode="AU" term="%22Yu+D%22">Yu D</searchLink>; Division of Life Science, The Hong Kong University of Science and Technology, Hong Kong, China.<br /><searchLink fieldCode="AU" term="%22Jiang+H%22">Jiang H</searchLink>; Division of Life Science, The Hong Kong University of Science and Technology, Hong Kong, China.<br /><searchLink fieldCode="AU" term="%22Hui+YC%22">Hui YC</searchLink>; Division of Life Science, The Hong Kong University of Science and Technology, Hong Kong, China.; School of Biological Sciences, The University of Hong Kong, Hong Kong, China.<br /><searchLink fieldCode="AU" term="%22Zhang+Q%22">Zhang Q</searchLink>; Division of Life Science, The Hong Kong University of Science and Technology, Hong Kong, China.; School of Biological Sciences, The University of Hong Kong, Hong Kong, China.<br /><searchLink fieldCode="AU" term="%22Li+W%22">Li W</searchLink>; The First Clinical College, Henan Medical University, Xinxiang, Henan, China.<br /><searchLink fieldCode="AU" term="%22Li+J%22">Li J</searchLink>; School of Biological Sciences, The University of Hong Kong, Hong Kong, China.<br /><searchLink fieldCode="AU" term="%22Lin+Z%22">Lin Z</searchLink>; School of Biological Sciences, The University of Hong Kong, Hong Kong, China.<br /><searchLink fieldCode="AU" term="%22Yin+Z%22">Yin Z</searchLink>; Division of Life Science, The Hong Kong University of Science and Technology, Hong Kong, China.<br /><searchLink fieldCode="AU" term="%22Wu+W%22">Wu W</searchLink>; School of Biological Sciences, The University of Hong Kong, Hong Kong, China.<br /><searchLink fieldCode="AU" term="%22Zhang+Y%22">Zhang Y</searchLink>; Biological Cryo-EM Center, The Hong Kong University of Science and Technology, Hong Kong, China.<br /><searchLink fieldCode="AU" term="%22Liu+N%22">Liu N</searchLink>; School of Biological Sciences, The University of Hong Kong, Hong Kong, China.<br /><searchLink fieldCode="AU" term="%22Kanemaki+MT%22">Kanemaki MT</searchLink>; National Institute of Genetics, Research Organization of Information and Systems (ROIS), Shizuoka, Japan.; Graduate Institute for Advanced Studies, SOKENDAI, Shizuoka, Japan.; Department of Biological Science, Graduate School of Science, The University of Tokyo, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Dang+S%22">Dang S</searchLink>; Division of Life Science, The Hong Kong University of Science and Technology, Hong Kong, China.<br /><searchLink fieldCode="AU" term="%22Zhai+Y%22">Zhai Y</searchLink>; Division of Life Science, The Hong Kong University of Science and Technology, Hong Kong, China. zhai@ust.hk.
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