Characterization of Alternaria alternata alternariol monomethyl ether with a potential antiproliferative activity by topoisomerases inhibition; molecular docking and dynamic simulations.
Saved in:
| Title: | Characterization of Alternaria alternata alternariol monomethyl ether with a potential antiproliferative activity by topoisomerases inhibition; molecular docking and dynamic simulations. |
|---|---|
| Authors: | El-Sayed ASA; Enzymology and Fungal Biotechnology Lab, Botany and Microbiology Department, Faculty of Science, Zagazig University, Zagazig, 44519, Egypt. ash.elsayed@gmail.com., Aboelez MO; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Sohag University, Sohag, 82524, Egypt., Ezelarab HAA; Department of Medicinal Chemistry, Faculty of Pharmacy, Minia University, Minia City, 61519, Egypt.; Medicinal Chemistry Department, Faculty of Pharmacy, Minia National University, New Minia City, 61519, Egypt., Ewedah TM; Pharmaceutics and Pharmaceutical Technology Department, Faculty of Pharmacy, Egyptian Russian University, Cairo, Egypt., El-Baz AF; Department of Industrial Biotechnology, Genetic Engineering and Biotechnology Research Institute, University of Sadat City, 32897, Sadat City, Egypt., Ashraf R; Faculty of Biotechnology, October University for Modern Sciences and Arts, Giza, Egypt., Diab A; Faculty of Biotechnology, October University for Modern Sciences and Arts, Giza, Egypt., Safwat G; Faculty of Biotechnology, October University for Modern Sciences and Arts, Giza, Egypt., Rady AM; Enzymology and Fungal Biotechnology Lab, Botany and Microbiology Department, Faculty of Science, Zagazig University, Zagazig, 44519, Egypt.; Faculty of Biotechnology, October University for Modern Sciences and Arts, Giza, Egypt., El-Mekkawy RM; Enzymology and Fungal Biotechnology Lab, Botany and Microbiology Department, Faculty of Science, Zagazig University, Zagazig, 44519, Egypt. |
| Source: | Scientific reports [Sci Rep] 2026 May 18; Vol. 16 (1). Date of Electronic Publication: 2026 May 18. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
|---|---|
| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 42151316 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
| IllustrationInfo | |
| Items | – Name: Title Label: Title Group: Ti Data: Characterization of Alternaria alternata alternariol monomethyl ether with a potential antiproliferative activity by topoisomerases inhibition; molecular docking and dynamic simulations. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22El-Sayed+ASA%22">El-Sayed ASA</searchLink>; Enzymology and Fungal Biotechnology Lab, Botany and Microbiology Department, Faculty of Science, Zagazig University, Zagazig, 44519, Egypt. ash.elsayed@gmail.com.<br /><searchLink fieldCode="AU" term="%22Aboelez+MO%22">Aboelez MO</searchLink>; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Sohag University, Sohag, 82524, Egypt.<br /><searchLink fieldCode="AU" term="%22Ezelarab+HAA%22">Ezelarab HAA</searchLink>; Department of Medicinal Chemistry, Faculty of Pharmacy, Minia University, Minia City, 61519, Egypt.; Medicinal Chemistry Department, Faculty of Pharmacy, Minia National University, New Minia City, 61519, Egypt.<br /><searchLink fieldCode="AU" term="%22Ewedah+TM%22">Ewedah TM</searchLink>; Pharmaceutics and Pharmaceutical Technology Department, Faculty of Pharmacy, Egyptian Russian University, Cairo, Egypt.<br /><searchLink fieldCode="AU" term="%22El-Baz+AF%22">El-Baz AF</searchLink>; Department of Industrial Biotechnology, Genetic Engineering and Biotechnology Research Institute, University of Sadat City, 32897, Sadat City, Egypt.<br /><searchLink fieldCode="AU" term="%22Ashraf+R%22">Ashraf R</searchLink>; Faculty of Biotechnology, October University for Modern Sciences and Arts, Giza, Egypt.<br /><searchLink fieldCode="AU" term="%22Diab+A%22">Diab A</searchLink>; Faculty of Biotechnology, October University for Modern Sciences and Arts, Giza, Egypt.<br /><searchLink fieldCode="AU" term="%22Safwat+G%22">Safwat G</searchLink>; Faculty of Biotechnology, October University for Modern Sciences and Arts, Giza, Egypt.<br /><searchLink fieldCode="AU" term="%22Rady+AM%22">Rady AM</searchLink>; Enzymology and Fungal Biotechnology Lab, Botany and Microbiology Department, Faculty of Science, Zagazig University, Zagazig, 44519, Egypt.; Faculty of Biotechnology, October University for Modern Sciences and Arts, Giza, Egypt.<br /><searchLink fieldCode="AU" term="%22El-Mekkawy+RM%22">El-Mekkawy RM</searchLink>; Enzymology and Fungal Biotechnology Lab, Botany and Microbiology Department, Faculty of Science, Zagazig University, Zagazig, 44519, Egypt. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101563288%22">Scientific reports</searchLink> [Sci Rep] 2026 May 18; Vol. 16 (1). <i>Date of Electronic Publication: </i>2026 May 18. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Publishing+Group%22">Nature Publishing Group </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101563288 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2045-2322 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220452322%22">20452322 </searchLink><i>NLM ISO Abbreviation: </i>Sci Rep <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=42151316 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1038/s41598-026-51757-8 Languages: – Code: eng Text: English Titles: – TitleFull: Characterization of Alternaria alternata alternariol monomethyl ether with a potential antiproliferative activity by topoisomerases inhibition; molecular docking and dynamic simulations. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: El-Sayed ASA – PersonEntity: Name: NameFull: Aboelez MO – PersonEntity: Name: NameFull: Ezelarab HAA – PersonEntity: Name: NameFull: Ewedah TM – PersonEntity: Name: NameFull: El-Baz AF – PersonEntity: Name: NameFull: Ashraf R – PersonEntity: Name: NameFull: Diab A – PersonEntity: Name: NameFull: Safwat G – PersonEntity: Name: NameFull: Rady AM – PersonEntity: Name: NameFull: El-Mekkawy RM IsPartOfRelationships: – BibEntity: Dates: – D: 18 M: 05 Text: 2026 May 18 Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 2045-2322 Numbering: – Type: volume Value: 16 – Type: issue Value: 1 Titles: – TitleFull: Scientific reports Type: main |
| ResultId | 1 |
