Standard-Dose Ursodeoxycholic Acid Improves Biochemical Liver Function and Fibrosis in Chronic Liver Disease: Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial.
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| Title: | Standard-Dose Ursodeoxycholic Acid Improves Biochemical Liver Function and Fibrosis in Chronic Liver Disease: Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial. |
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| Authors: | Chang Y; Institute for Digestive Research, Digestive Disease Center, Department of Internal Medicine, Soonchunhyang University College of Medicine, Seoul, Korea., Cho YK; Division of Gastroenterology, Department of Internal Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea., Kim YS; Department of Internal Medicine, Soonchunhyang University College of Medicine, Bucheon, Korea., Kim SE; Division of Gastroenterology, Department of Internal Medicine, Hallym University Sacred Heart Hospital, Hallym University College of Medicine, Anyang, Korea., Cheon GJ; Department of Internal Medicine, Gangneung Asan Hospital, University of Ulsan College of Medicine, Gangneung, Korea., Kim JH; Department of Internal Medicine, Korea University College of Medicine, Seoul, Korea., Yang H; Department of Internal Medicine, Eunpyeong St. Mary's hospital, Seoul, Korea., Kim W; Department of Internal Medicine, Seoul Metropolitan Government-Seoul National University Boramae Medical Center, Seoul National University College of Medicine, Seoul, Korea., Ahn SB; Department of Internal Medicine, Nowon Eulji Medical Center, Eulji University, Seoul, Korea., Yoon EL; Department of Internal Medicine, Hanyang University College of Medicine, Seoul, Korea., Cheong JY; Department of Gastroenterology, Ajou University Hospital, Suwon, Korea., Lee JW; Department of Internal Medicine, Inha University Hospital, Inha University School of Medicine, Incheon, Korea., Kim MY; Department of Internal Medicine, Yonsei University, Wonju College of Medicine, Wonju, Korea., Kim HJ; Department of Internal Medicine, Chung-Ang University College of Medicine, Seoul, Korea., Lee SH; Department of Internal Medicine, Soonchunhyang University College of Medicine, Cheonan, Korea., Cho EY; Department of Internal Medicine, Wonkwang University School of Medicine, Iksan, Korea., Choi NR; Department of Internal Medicine, Ewha Womans University Mokdong Hospital, Ewha Womans University College of Medicine, Seoul, Korea., Lee HW; Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea., Kim KM; Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea., Choe WH; Department of Internal Medicine, Konkuk University School of Medicine, Seoul, Korea., Yu JM; Daewoong Pharmaceutical Co., Ltd., Seoul, Korea., Kim SY; Daewoong Pharmaceutical Co., Ltd., Seoul, Korea., Jang JY; Institute for Digestive Research, Digestive Disease Center, Department of Internal Medicine, Soonchunhyang University College of Medicine, Seoul, Korea. jyjang@schmc.ac.kr. |
| Source: | Journal of Korean medical science [J Korean Med Sci] 2026 May 18; Vol. 41 (19), pp. e89. Date of Electronic Publication: 2026 May 18. |
| Publication Type: | Journal Article; Randomized Controlled Trial; Multicenter Study; Clinical Trial, Phase IV |
| Journal Info: | Publisher: Korean Academy of Medical Science Country of Publication: Korea (South) NLM ID: 8703518 Publication Model: Electronic Cited Medium: Internet ISSN: 1598-6357 (Electronic) Linking ISSN: 10118934 NLM ISO Abbreviation: J Korean Med Sci Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 42153228 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Standard-Dose Ursodeoxycholic Acid Improves Biochemical Liver Function and Fibrosis in Chronic Liver Disease: Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Chang+Y%22">Chang Y</searchLink>; Institute for Digestive Research, Digestive Disease Center, Department of Internal Medicine, Soonchunhyang University College of Medicine, Seoul, Korea.<br /><searchLink fieldCode="AU" term="%22Cho+YK%22">Cho YK</searchLink>; Division of Gastroenterology, Department of Internal Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea.<br /><searchLink fieldCode="AU" term="%22Kim+YS%22">Kim YS</searchLink>; Department of Internal Medicine, Soonchunhyang University College of Medicine, Bucheon, Korea.<br /><searchLink fieldCode="AU" term="%22Kim+SE%22">Kim SE</searchLink>; Division of Gastroenterology, Department of Internal Medicine, Hallym University Sacred Heart Hospital, Hallym University College of Medicine, Anyang, Korea.<br /><searchLink fieldCode="AU" term="%22Cheon+GJ%22">Cheon GJ</searchLink>; Department of Internal Medicine, Gangneung Asan Hospital, University of Ulsan College of Medicine, Gangneung, Korea.<br /><searchLink fieldCode="AU" term="%22Kim+JH%22">Kim JH</searchLink>; Department of Internal Medicine, Korea University College of Medicine, Seoul, Korea.<br /><searchLink fieldCode="AU" term="%22Yang+H%22">Yang H</searchLink>; Department of Internal Medicine, Eunpyeong St. Mary's hospital, Seoul, Korea.<br /><searchLink fieldCode="AU" term="%22Kim+W%22">Kim W</searchLink>; Department of Internal Medicine, Seoul Metropolitan Government-Seoul National University Boramae Medical Center, Seoul National University College of Medicine, Seoul, Korea.<br /><searchLink fieldCode="AU" term="%22Ahn+SB%22">Ahn SB</searchLink>; Department of Internal Medicine, Nowon Eulji Medical Center, Eulji University, Seoul, Korea.<br /><searchLink fieldCode="AU" term="%22Yoon+EL%22">Yoon EL</searchLink>; Department of Internal Medicine, Hanyang University College of Medicine, Seoul, Korea.<br /><searchLink fieldCode="AU" term="%22Cheong+JY%22">Cheong JY</searchLink>; Department of Gastroenterology, Ajou University Hospital, Suwon, Korea.<br /><searchLink fieldCode="AU" term="%22Lee+JW%22">Lee JW</searchLink>; Department of Internal Medicine, Inha University Hospital, Inha University School of Medicine, Incheon, Korea.<br /><searchLink fieldCode="AU" term="%22Kim+MY%22">Kim MY</searchLink>; Department of Internal Medicine, Yonsei University, Wonju College of Medicine, Wonju, Korea.<br /><searchLink fieldCode="AU" term="%22Kim+HJ%22">Kim HJ</searchLink>; Department of Internal Medicine, Chung-Ang University College of Medicine, Seoul, Korea.<br /><searchLink fieldCode="AU" term="%22Lee+SH%22">Lee SH</searchLink>; Department of Internal Medicine, Soonchunhyang University College of Medicine, Cheonan, Korea.<br /><searchLink fieldCode="AU" term="%22Cho+EY%22">Cho EY</searchLink>; Department of Internal Medicine, Wonkwang University School of Medicine, Iksan, Korea.<br /><searchLink fieldCode="AU" term="%22Choi+NR%22">Choi NR</searchLink>; Department of Internal Medicine, Ewha Womans University Mokdong Hospital, Ewha Womans University College of Medicine, Seoul, Korea.<br /><searchLink fieldCode="AU" term="%22Lee+HW%22">Lee HW</searchLink>; Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.<br /><searchLink fieldCode="AU" term="%22Kim+KM%22">Kim KM</searchLink>; Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.<br /><searchLink fieldCode="AU" term="%22Choe+WH%22">Choe WH</searchLink>; Department of Internal Medicine, Konkuk University School of Medicine, Seoul, Korea.<br /><searchLink fieldCode="AU" term="%22Yu+JM%22">Yu JM</searchLink>; Daewoong Pharmaceutical Co., Ltd., Seoul, Korea.<br /><searchLink fieldCode="AU" term="%22Kim+SY%22">Kim SY</searchLink>; Daewoong Pharmaceutical Co., Ltd., Seoul, Korea.<br /><searchLink fieldCode="AU" term="%22Jang+JY%22">Jang JY</searchLink>; Institute for Digestive Research, Digestive Disease Center, Department of Internal Medicine, Soonchunhyang University College of Medicine, Seoul, Korea. jyjang@schmc.ac.kr. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%228703518%22">Journal of Korean medical science</searchLink> [J Korean Med Sci] 2026 May 18; Vol. 41 (19), pp. e89. <i>Date of Electronic Publication: </i>2026 May 18. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Randomized Controlled Trial; Multicenter Study; Clinical Trial, Phase IV – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Korean+Academy+of+Medical+Science%22">Korean Academy of Medical Science </searchLink><i>Country of Publication: </i>Korea (South) <i>NLM ID: </i>8703518 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1598-6357 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2210118934%22">10118934 </searchLink><i>NLM ISO Abbreviation: </i>J Korean Med Sci <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=42153228 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.3346/jkms.2026.41.e89 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: e89 Titles: – TitleFull: Standard-Dose Ursodeoxycholic Acid Improves Biochemical Liver Function and Fibrosis in Chronic Liver Disease: Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Chang Y – PersonEntity: Name: NameFull: Cho YK – PersonEntity: Name: NameFull: Kim YS – PersonEntity: Name: NameFull: Kim SE – PersonEntity: Name: NameFull: Cheon GJ – PersonEntity: Name: NameFull: Kim JH – PersonEntity: Name: NameFull: Yang H – PersonEntity: Name: NameFull: Kim W – PersonEntity: Name: NameFull: Ahn SB – PersonEntity: Name: NameFull: Yoon EL – PersonEntity: Name: NameFull: Cheong JY – PersonEntity: Name: NameFull: Lee JW – PersonEntity: Name: NameFull: Kim MY – PersonEntity: Name: NameFull: Kim HJ – PersonEntity: Name: NameFull: Lee SH – PersonEntity: Name: NameFull: Cho EY – PersonEntity: Name: NameFull: Choi NR – PersonEntity: Name: NameFull: Lee HW – PersonEntity: Name: NameFull: Kim KM – PersonEntity: Name: NameFull: Choe WH – PersonEntity: Name: NameFull: Yu JM – PersonEntity: Name: NameFull: Kim SY – PersonEntity: Name: NameFull: Jang JY IsPartOfRelationships: – BibEntity: Dates: – D: 18 M: 05 Text: 2026 May 18 Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 1598-6357 Numbering: – Type: volume Value: 41 – Type: issue Value: 19 Titles: – TitleFull: Journal of Korean medical science Type: main |
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