Investigation of the modulatory effects of fabomotizole and/or sertraline on cisplatin nephrotoxicity via in vivo and in vitro approaches: insights into the role of Sig-1R/ERK1/2 signaling in regulating mitochondrial dynamics and apoptotic cellular death.
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| Title: | Investigation of the modulatory effects of fabomotizole and/or sertraline on cisplatin nephrotoxicity via in vivo and in vitro approaches: insights into the role of Sig-1R/ERK1/2 signaling in regulating mitochondrial dynamics and apoptotic cellular death. |
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| Authors: | Zaki AM; Postgraduate Program in Pharmacology and Toxicology, Faculty of Pharmacy, Cairo University, Cairo, 11562, Egypt., Khattab MA; Department of Cytology and Histology, Faculty of Veterinary Medicine, Cairo University, Cairo, 12211, Egypt., El-Tanbouly DM; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Cairo University, Kasr El-Aini St., Cairo, 11562, Egypt. dalia.eltanbouly@pharma.cu.edu.eg., Abdelsalam RM; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Cairo University, Kasr El-Aini St., Cairo, 11562, Egypt.; Department of Pharmacology and Toxicology, School of Pharmacy, New Giza University, Giza, Egypt., Zaki HF; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Cairo University, Kasr El-Aini St., Cairo, 11562, Egypt., Abdelghany TM; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Cairo University, Kasr El-Aini St., Cairo, 11562, Egypt. |
| Source: | Naunyn-Schmiedeberg's archives of pharmacology [Naunyn Schmiedebergs Arch Pharmacol] 2026 May 19. Date of Electronic Publication: 2026 May 19. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Springer Verlag Country of Publication: Germany NLM ID: 0326264 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-1912 (Electronic) Linking ISSN: 00281298 NLM ISO Abbreviation: Naunyn Schmiedebergs Arch Pharmacol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 42154013 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Investigation of the modulatory effects of fabomotizole and/or sertraline on cisplatin nephrotoxicity via in vivo and in vitro approaches: insights into the role of Sig-1R/ERK1/2 signaling in regulating mitochondrial dynamics and apoptotic cellular death. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Zaki+AM%22">Zaki AM</searchLink>; Postgraduate Program in Pharmacology and Toxicology, Faculty of Pharmacy, Cairo University, Cairo, 11562, Egypt.<br /><searchLink fieldCode="AU" term="%22Khattab+MA%22">Khattab MA</searchLink>; Department of Cytology and Histology, Faculty of Veterinary Medicine, Cairo University, Cairo, 12211, Egypt.<br /><searchLink fieldCode="AU" term="%22El-Tanbouly+DM%22">El-Tanbouly DM</searchLink>; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Cairo University, Kasr El-Aini St., Cairo, 11562, Egypt. dalia.eltanbouly@pharma.cu.edu.eg.<br /><searchLink fieldCode="AU" term="%22Abdelsalam+RM%22">Abdelsalam RM</searchLink>; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Cairo University, Kasr El-Aini St., Cairo, 11562, Egypt.; Department of Pharmacology and Toxicology, School of Pharmacy, New Giza University, Giza, Egypt.<br /><searchLink fieldCode="AU" term="%22Zaki+HF%22">Zaki HF</searchLink>; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Cairo University, Kasr El-Aini St., Cairo, 11562, Egypt.<br /><searchLink fieldCode="AU" term="%22Abdelghany+TM%22">Abdelghany TM</searchLink>; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Cairo University, Kasr El-Aini St., Cairo, 11562, Egypt. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%220326264%22">Naunyn-Schmiedeberg's archives of pharmacology</searchLink> [Naunyn Schmiedebergs Arch Pharmacol] 2026 May 19. <i>Date of Electronic Publication: </i>2026 May 19. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer+Verlag%22">Springer Verlag </searchLink><i>Country of Publication: </i>Germany <i>NLM ID: </i>0326264 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1432-1912 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200281298%22">00281298 </searchLink><i>NLM ISO Abbreviation: </i>Naunyn Schmiedebergs Arch Pharmacol <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=42154013 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1007/s00210-026-05434-2 Languages: – Code: eng Text: English Titles: – TitleFull: Investigation of the modulatory effects of fabomotizole and/or sertraline on cisplatin nephrotoxicity via in vivo and in vitro approaches: insights into the role of Sig-1R/ERK1/2 signaling in regulating mitochondrial dynamics and apoptotic cellular death. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Zaki AM – PersonEntity: Name: NameFull: Khattab MA – PersonEntity: Name: NameFull: El-Tanbouly DM – PersonEntity: Name: NameFull: Abdelsalam RM – PersonEntity: Name: NameFull: Zaki HF – PersonEntity: Name: NameFull: Abdelghany TM IsPartOfRelationships: – BibEntity: Dates: – D: 19 M: 05 Text: 2026 May 19 Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 1432-1912 Titles: – TitleFull: Naunyn-Schmiedeberg's archives of pharmacology Type: main |
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