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Deficiency of muscular dystrophy-related gene JAG2 causes NOTCH signaling dysfunction in muscle stem cells.

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Title: Deficiency of muscular dystrophy-related gene JAG2 causes NOTCH signaling dysfunction in muscle stem cells.
Authors: Tanaka M; Stem Cell Institute and.; Greg Marzolf Jr. Muscular Dystrophy Center and Department of Neurology, University of Minnesota Medical School, Minneapolis, Minnesota, USA., Kim NC; Department of Pharmacy Practice and Pharmaceutical Sciences, University of Minnesota College of Pharmacy, Duluth, Minnesota, USA., Draper I; Molecular Cardiology Research Institute, Tufts Medical Center, Boston, Massachusetts, USA., Littel HR; Greg Marzolf Jr. Muscular Dystrophy Center and Department of Neurology, University of Minnesota Medical School, Minneapolis, Minnesota, USA., Gunasekaran M; Greg Marzolf Jr. Muscular Dystrophy Center and Department of Neurology, University of Minnesota Medical School, Minneapolis, Minnesota, USA., Turner J; Greg Marzolf Jr. Muscular Dystrophy Center and Department of Neurology, University of Minnesota Medical School, Minneapolis, Minnesota, USA., Wells NM; Greg Marzolf Jr. Muscular Dystrophy Center and Department of Neurology, University of Minnesota Medical School, Minneapolis, Minnesota, USA., Mujteba Q; Greg Marzolf Jr. Muscular Dystrophy Center and Department of Neurology, University of Minnesota Medical School, Minneapolis, Minnesota, USA., Asakura Y; Stem Cell Institute and.; Greg Marzolf Jr. Muscular Dystrophy Center and Department of Neurology, University of Minnesota Medical School, Minneapolis, Minnesota, USA., Kang PB; Greg Marzolf Jr. Muscular Dystrophy Center and Department of Neurology, University of Minnesota Medical School, Minneapolis, Minnesota, USA.; Institute for Translational Neuroscience, University of Minnesota Medical School, Minneapolis, Minnesota, USA., Asakura A; Stem Cell Institute and.; Greg Marzolf Jr. Muscular Dystrophy Center and Department of Neurology, University of Minnesota Medical School, Minneapolis, Minnesota, USA.
Source: The Journal of clinical investigation [J Clin Invest] 2026 May 19; Vol. 136 (13). Date of Electronic Publication: 2026 May 19 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model: eCollection Cited Medium: Internet ISSN: 1558-8238 (Electronic) Linking ISSN: 00219738 NLM ISO Abbreviation: J Clin Invest Subsets: MEDLINE
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  Data: Deficiency of muscular dystrophy-related gene JAG2 causes NOTCH signaling dysfunction in muscle stem cells.
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  Data: <searchLink fieldCode="AU" term="%22Tanaka+M%22">Tanaka M</searchLink>; Stem Cell Institute and.; Greg Marzolf Jr. Muscular Dystrophy Center and Department of Neurology, University of Minnesota Medical School, Minneapolis, Minnesota, USA.<br /><searchLink fieldCode="AU" term="%22Kim+NC%22">Kim NC</searchLink>; Department of Pharmacy Practice and Pharmaceutical Sciences, University of Minnesota College of Pharmacy, Duluth, Minnesota, USA.<br /><searchLink fieldCode="AU" term="%22Draper+I%22">Draper I</searchLink>; Molecular Cardiology Research Institute, Tufts Medical Center, Boston, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Littel+HR%22">Littel HR</searchLink>; Greg Marzolf Jr. Muscular Dystrophy Center and Department of Neurology, University of Minnesota Medical School, Minneapolis, Minnesota, USA.<br /><searchLink fieldCode="AU" term="%22Gunasekaran+M%22">Gunasekaran M</searchLink>; Greg Marzolf Jr. Muscular Dystrophy Center and Department of Neurology, University of Minnesota Medical School, Minneapolis, Minnesota, USA.<br /><searchLink fieldCode="AU" term="%22Turner+J%22">Turner J</searchLink>; Greg Marzolf Jr. Muscular Dystrophy Center and Department of Neurology, University of Minnesota Medical School, Minneapolis, Minnesota, USA.<br /><searchLink fieldCode="AU" term="%22Wells+NM%22">Wells NM</searchLink>; Greg Marzolf Jr. Muscular Dystrophy Center and Department of Neurology, University of Minnesota Medical School, Minneapolis, Minnesota, USA.<br /><searchLink fieldCode="AU" term="%22Mujteba+Q%22">Mujteba Q</searchLink>; Greg Marzolf Jr. Muscular Dystrophy Center and Department of Neurology, University of Minnesota Medical School, Minneapolis, Minnesota, USA.<br /><searchLink fieldCode="AU" term="%22Asakura+Y%22">Asakura Y</searchLink>; Stem Cell Institute and.; Greg Marzolf Jr. Muscular Dystrophy Center and Department of Neurology, University of Minnesota Medical School, Minneapolis, Minnesota, USA.<br /><searchLink fieldCode="AU" term="%22Kang+PB%22">Kang PB</searchLink>; Greg Marzolf Jr. Muscular Dystrophy Center and Department of Neurology, University of Minnesota Medical School, Minneapolis, Minnesota, USA.; Institute for Translational Neuroscience, University of Minnesota Medical School, Minneapolis, Minnesota, USA.<br /><searchLink fieldCode="AU" term="%22Asakura+A%22">Asakura A</searchLink>; Stem Cell Institute and.; Greg Marzolf Jr. Muscular Dystrophy Center and Department of Neurology, University of Minnesota Medical School, Minneapolis, Minnesota, USA.
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  Data: <searchLink fieldCode="JN" term="%227802877%22">The Journal of clinical investigation</searchLink> [J Clin Invest] 2026 May 19; Vol. 136 (13). <i>Date of Electronic Publication: </i>2026 May 19 (<i>Print Publication: </i>2026).
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        Value: 10.1172/JCI198639
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        Text: English
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              Text: 2026 May 19
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