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Potential molecular targets on which methylene blue acts to promote its effects on cardiac electrophysiology, myocardial injury, and oxidative stress in spontaneously hypertensive rats submitted to cardiac ischemia and reperfusion.

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Title: Potential molecular targets on which methylene blue acts to promote its effects on cardiac electrophysiology, myocardial injury, and oxidative stress in spontaneously hypertensive rats submitted to cardiac ischemia and reperfusion.
Authors: Lima RY; Universidade Federal de São Paulo - Postgraduate Program in Cardiology - São Paulo (SP), Brazil., Govato TCP; Universidade Federal de São Paulo - Postgraduate Program in Cardiology - São Paulo (SP), Brazil., Araújo EA; Universidade Federal de São Paulo - Postgraduate Program in Cardiology - São Paulo (SP), Brazil., Pires-Oliveira M; Centro Universitário UNIME - Medical Course - Department of Medicine - Lauro de Freitas (BA), Brazil., Sousa PSA; Universidade Federal do Delta do Parnaíba - Research Center on Biodiversity and Biotechnology - Parnaíba (PI), Brazil.; Universidade Federal do Maranhão - São Bernardo (MA), Brazil., Rocha JA; Universidade Federal do Delta do Parnaíba - Research Center on Biodiversity and Biotechnology - Parnaíba (PI), Brazil.; Universidade Federal do Maranhão - São Bernardo (MA), Brazil., Véras LMC; Universidade Federal do Delta do Parnaíba - Research Center on Biodiversity and Biotechnology - Parnaíba (PI), Brazil., Pinto SAG; Universidade Federal de São Paulo - Postgraduate Program in Cardiology - São Paulo (SP), Brazil., Caricati-Neto A; Universidade Federal de São Paulo - Department of Pharmacology - São Paulo (SP), Brazil., Tallo FS; Universidade Federal de São Paulo - Postgraduate Program in Interdisciplinary Surgical Science - São Paulo (SP), Brazil., Silva CMC; Universidade Federal de São Paulo - Postgraduate Program in Cardiology - São Paulo (SP), Brazil., Menezes-Rodrigues FS; Universidade Federal de São Paulo - Postgraduate Program in Cardiology - São Paulo (SP), Brazil.; Universidade Federal de São Paulo - Postgraduate Program in Interdisciplinary Surgical Science - São Paulo (SP), Brazil.
Source: Acta cirurgica brasileira [Acta Cir Bras] 2026 May 18; Vol. 41, pp. e411826. Date of Electronic Publication: 2026 May 18 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Sociedade Brasileira Para O Desenvolvimento Da Pesquisa Em Cirurgia Curso De Pos-Graduacao Em Tecnica Operatoria E Cirurgia Experimental Escola Paulista De Medicina Country of Publication: Brazil NLM ID: 9103983 Publication Model: eCollection Cited Medium: Internet ISSN: 1678-2674 (Electronic) Linking ISSN: 01028650 NLM ISO Abbreviation: Acta Cir Bras Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1678-2674
DOI:10.1590/acb411826