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Proteomic Analysis on Human Islets Suggests Nucleocytoplasmic Transport as a Mechanism of PERK Attenuation Effects in Diabetes.

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Title: Proteomic Analysis on Human Islets Suggests Nucleocytoplasmic Transport as a Mechanism of PERK Attenuation Effects in Diabetes.
Authors: Park YS; Division of Endocrinology and Metabolism, Department of Internal Medicine, Seoul National University Hospital, Seoul, Republic of Korea., Yun S; Proteomics Core Facility, Biomedical Research Institute, Seoul National University Hospital, Seoul, Republic of Korea; Department of Transdisciplinary Medicine, Seoul National University Hospital, Seoul, Republic of Korea., Sim MS; Division of Endocrinology and Metabolism, Department of Internal Medicine, Seoul National University Hospital, Seoul, Republic of Korea., An EJ; Division of Endocrinology and Metabolism, Department of Internal Medicine, Seoul National University Hospital, Seoul, Republic of Korea., Lee J; Proteomics Core Facility, Biomedical Research Institute, Seoul National University Hospital, Seoul, Republic of Korea; Department of Transdisciplinary Medicine, Seoul National University Hospital, Seoul, Republic of Korea; Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, Republic of Korea., Ha EH; Division of Endocrinology and Metabolism, Department of Internal Medicine, Seoul National University Hospital, Seoul, Republic of Korea., Jang JY; Department of Surgery and Cancer Research Institute, Seoul National University College of Medicine, Seoul, Republic of Korea., Kwon W; Department of Surgery and Cancer Research Institute, Seoul National University College of Medicine, Seoul, Republic of Korea. Electronic address: willdoc78@gmail.com., Han D; Proteomics Core Facility, Biomedical Research Institute, Seoul National University Hospital, Seoul, Republic of Korea; Department of Transdisciplinary Medicine, Seoul National University Hospital, Seoul, Republic of Korea. Electronic address: hdh03@snu.ac.kr., Jung HS; Division of Endocrinology and Metabolism, Department of Internal Medicine, Seoul National University Hospital, Seoul, Republic of Korea. Electronic address: jungjhs@gmail.com.
Source: Molecular & cellular proteomics : MCP [Mol Cell Proteomics] 2026 Jun; Vol. 25 (6), pp. 101588. Date of Electronic Publication: 2026 May 18.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 101125647 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1535-9484 (Electronic) Linking ISSN: 15359476 NLM ISO Abbreviation: Mol Cell Proteomics Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Proteomic Analysis on Human Islets Suggests Nucleocytoplasmic Transport as a Mechanism of PERK Attenuation Effects in Diabetes.
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  Data: <searchLink fieldCode="AU" term="%22Park+YS%22">Park YS</searchLink>; Division of Endocrinology and Metabolism, Department of Internal Medicine, Seoul National University Hospital, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Yun+S%22">Yun S</searchLink>; Proteomics Core Facility, Biomedical Research Institute, Seoul National University Hospital, Seoul, Republic of Korea; Department of Transdisciplinary Medicine, Seoul National University Hospital, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Sim+MS%22">Sim MS</searchLink>; Division of Endocrinology and Metabolism, Department of Internal Medicine, Seoul National University Hospital, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22An+EJ%22">An EJ</searchLink>; Division of Endocrinology and Metabolism, Department of Internal Medicine, Seoul National University Hospital, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Lee+J%22">Lee J</searchLink>; Proteomics Core Facility, Biomedical Research Institute, Seoul National University Hospital, Seoul, Republic of Korea; Department of Transdisciplinary Medicine, Seoul National University Hospital, Seoul, Republic of Korea; Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Ha+EH%22">Ha EH</searchLink>; Division of Endocrinology and Metabolism, Department of Internal Medicine, Seoul National University Hospital, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Jang+JY%22">Jang JY</searchLink>; Department of Surgery and Cancer Research Institute, Seoul National University College of Medicine, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kwon+W%22">Kwon W</searchLink>; Department of Surgery and Cancer Research Institute, Seoul National University College of Medicine, Seoul, Republic of Korea. Electronic address: willdoc78@gmail.com.<br /><searchLink fieldCode="AU" term="%22Han+D%22">Han D</searchLink>; Proteomics Core Facility, Biomedical Research Institute, Seoul National University Hospital, Seoul, Republic of Korea; Department of Transdisciplinary Medicine, Seoul National University Hospital, Seoul, Republic of Korea. Electronic address: hdh03@snu.ac.kr.<br /><searchLink fieldCode="AU" term="%22Jung+HS%22">Jung HS</searchLink>; Division of Endocrinology and Metabolism, Department of Internal Medicine, Seoul National University Hospital, Seoul, Republic of Korea. Electronic address: jungjhs@gmail.com.
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  Data: <searchLink fieldCode="JN" term="%22101125647%22">Molecular & cellular proteomics : MCP</searchLink> [Mol Cell Proteomics] 2026 Jun; Vol. 25 (6), pp. 101588. <i>Date of Electronic Publication: </i>2026 May 18.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier+Inc%2E+on+behalf+of+American+Society+for+Biochemistry+and+Molecular+Biology%22">Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101125647 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1535-9484 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2215359476%22">15359476 </searchLink><i>NLM ISO Abbreviation: </i>Mol Cell Proteomics <i>Subsets: </i>MEDLINE
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        Value: 10.1016/j.mcpro.2026.101588
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              Text: 2026 Jun
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              Y: 2026
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