Antifungal-induced DNA dynamics and chitin remodelling across Cryptococcus spp. and the novel broad-spectrum anti-cryptococcal candidate CPTH2.

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Title: Antifungal-induced DNA dynamics and chitin remodelling across Cryptococcus spp. and the novel broad-spectrum anti-cryptococcal candidate CPTH2.
Authors: Tamayo D; Medical Research Council Centre for Medical Mycology, Department of Biosciences, Faculty of Health and Life Sciences, University of Exeter, Exeter, EX4 4QD, UK., Anand R; Medical Research Council Centre for Medical Mycology, Department of Biosciences, Faculty of Health and Life Sciences, University of Exeter, Exeter, EX4 4QD, UK., Helmstetter N; Medical Research Council Centre for Medical Mycology, Department of Biosciences, Faculty of Health and Life Sciences, University of Exeter, Exeter, EX4 4QD, UK., Engelthaler DM; Arizona State University, Tempe, USA.; Translational Genomics Research Institute, Flagstaff, AZ, USA., Fisher MC; MRC Centre for Global Infectious Disease Analysis, Imperial College School of Public Health, Imperial College London, London, W12 0BZ, UK., May RC; Institute of Microbiology and Infection, School of Biosciences, University of Birmingham, Birmingham, B15 2TT, UK., Farrer RA; Medical Research Council Centre for Medical Mycology, Department of Biosciences, Faculty of Health and Life Sciences, University of Exeter, Exeter, EX4 4QD, UK. R.Farrer@exeter.ac.uk.
Source: Scientific reports [Sci Rep] 2026 May 19; Vol. 16 (1). Date of Electronic Publication: 2026 May 19.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE
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  Data: Antifungal-induced DNA dynamics and chitin remodelling across Cryptococcus spp. and the novel broad-spectrum anti-cryptococcal candidate CPTH2.
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  Data: <searchLink fieldCode="AU" term="%22Tamayo+D%22">Tamayo D</searchLink>; Medical Research Council Centre for Medical Mycology, Department of Biosciences, Faculty of Health and Life Sciences, University of Exeter, Exeter, EX4 4QD, UK.<br /><searchLink fieldCode="AU" term="%22Anand+R%22">Anand R</searchLink>; Medical Research Council Centre for Medical Mycology, Department of Biosciences, Faculty of Health and Life Sciences, University of Exeter, Exeter, EX4 4QD, UK.<br /><searchLink fieldCode="AU" term="%22Helmstetter+N%22">Helmstetter N</searchLink>; Medical Research Council Centre for Medical Mycology, Department of Biosciences, Faculty of Health and Life Sciences, University of Exeter, Exeter, EX4 4QD, UK.<br /><searchLink fieldCode="AU" term="%22Engelthaler+DM%22">Engelthaler DM</searchLink>; Arizona State University, Tempe, USA.; Translational Genomics Research Institute, Flagstaff, AZ, USA.<br /><searchLink fieldCode="AU" term="%22Fisher+MC%22">Fisher MC</searchLink>; MRC Centre for Global Infectious Disease Analysis, Imperial College School of Public Health, Imperial College London, London, W12 0BZ, UK.<br /><searchLink fieldCode="AU" term="%22May+RC%22">May RC</searchLink>; Institute of Microbiology and Infection, School of Biosciences, University of Birmingham, Birmingham, B15 2TT, UK.<br /><searchLink fieldCode="AU" term="%22Farrer+RA%22">Farrer RA</searchLink>; Medical Research Council Centre for Medical Mycology, Department of Biosciences, Faculty of Health and Life Sciences, University of Exeter, Exeter, EX4 4QD, UK. R.Farrer@exeter.ac.uk.
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  Data: <searchLink fieldCode="JN" term="%22101563288%22">Scientific reports</searchLink> [Sci Rep] 2026 May 19; Vol. 16 (1). <i>Date of Electronic Publication: </i>2026 May 19.
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