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Host cell protein impurities in therapeutic proteins: overview of advances in detection, nonconventional removal technologies and immunogenicity assessment.

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Title: Host cell protein impurities in therapeutic proteins: overview of advances in detection, nonconventional removal technologies and immunogenicity assessment.
Authors: Alhuthali S; Chemical and Materials Engineering Department, Faculty of Engineering, King Abdulaziz University, Jeddah, 21589, Saudi Arabia. s.alhuthali15@imperial.ac.uk.; Department of Chemical Engineering, Imperial College London, London, SW7 2AZ, UK. s.alhuthali15@imperial.ac.uk., Pauzi SM; Department of Chemical Engineering, Imperial College London, London, SW7 2AZ, UK., Kontoravdi C; Department of Chemical Engineering, Imperial College London, London, SW7 2AZ, UK.
Source: Journal of biological engineering [J Biol Eng] 2026 May 19; Vol. 20 (1). Date of Electronic Publication: 2026 May 19.
Publication Type: Journal Article; Review
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101306640 Publication Model: Electronic Cited Medium: Print ISSN: 1754-1611 (Print) Linking ISSN: 17541611 NLM ISO Abbreviation: J Biol Eng Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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PubType: Academic Journal
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  Data: Host cell protein impurities in therapeutic proteins: overview of advances in detection, nonconventional removal technologies and immunogenicity assessment.
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  Data: <searchLink fieldCode="AU" term="%22Alhuthali+S%22">Alhuthali S</searchLink>; Chemical and Materials Engineering Department, Faculty of Engineering, King Abdulaziz University, Jeddah, 21589, Saudi Arabia. s.alhuthali15@imperial.ac.uk.; Department of Chemical Engineering, Imperial College London, London, SW7 2AZ, UK. s.alhuthali15@imperial.ac.uk.<br /><searchLink fieldCode="AU" term="%22Pauzi+SM%22">Pauzi SM</searchLink>; Department of Chemical Engineering, Imperial College London, London, SW7 2AZ, UK.<br /><searchLink fieldCode="AU" term="%22Kontoravdi+C%22">Kontoravdi C</searchLink>; Department of Chemical Engineering, Imperial College London, London, SW7 2AZ, UK.
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  Data: <searchLink fieldCode="JN" term="%22101306640%22">Journal of biological engineering</searchLink> [J Biol Eng] 2026 May 19; Vol. 20 (1). <i>Date of Electronic Publication: </i>2026 May 19.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central%22">BioMed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101306640 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Print <i>ISSN: </i>1754-1611 (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2217541611%22">17541611 </searchLink><i>NLM ISO Abbreviation: </i>J Biol Eng <i>Subsets: </i>PubMed not MEDLINE
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        Value: 10.1186/s13036-026-00685-2
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        Text: English
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      – TitleFull: Host cell protein impurities in therapeutic proteins: overview of advances in detection, nonconventional removal technologies and immunogenicity assessment.
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            NameFull: Alhuthali S
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            – D: 19
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              Text: 2026 May 19
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              Y: 2026
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