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Listening for Alzheimer's clues: machine learning analysis of multidomain speech features for cognitive impairment screening.

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Title: Listening for Alzheimer's clues: machine learning analysis of multidomain speech features for cognitive impairment screening.
Authors: Blazquez-Folch J; Ace Alzheimer Center Barcelona - Universitat Internacional de Catalunya, Barcelona, Spain., Calm B; Ace Alzheimer Center Barcelona - Universitat Internacional de Catalunya, Barcelona, Spain., Hinojosa-Calleja A; Ace Alzheimer Center Barcelona - Universitat Internacional de Catalunya, Barcelona, Spain., García-Gutiérrez F; Ace Alzheimer Center Barcelona - Universitat Internacional de Catalunya, Barcelona, Spain., Alegret M; Ace Alzheimer Center Barcelona - Universitat Internacional de Catalunya, Barcelona, Spain.; Networking Research Center on Neurodegenerative Diseases (CIBERNED), Instituto de Salud Carlos III, Madrid, Spain., Muñoz N; Ace Alzheimer Center Barcelona - Universitat Internacional de Catalunya, Barcelona, Spain., Cano A; Ace Alzheimer Center Barcelona - Universitat Internacional de Catalunya, Barcelona, Spain., Fernández MV; Ace Alzheimer Center Barcelona - Universitat Internacional de Catalunya, Barcelona, Spain., Miguel A; Ace Alzheimer Center Barcelona - Universitat Internacional de Catalunya, Barcelona, Spain., Solivar A; Ace Alzheimer Center Barcelona - Universitat Internacional de Catalunya, Barcelona, Spain., De Rojas I; Ace Alzheimer Center Barcelona - Universitat Internacional de Catalunya, Barcelona, Spain.; Networking Research Center on Neurodegenerative Diseases (CIBERNED), Instituto de Salud Carlos III, Madrid, Spain., Valenzuela-Seba A; Ace Alzheimer Center Barcelona - Universitat Internacional de Catalunya, Barcelona, Spain., García-González P; Ace Alzheimer Center Barcelona - Universitat Internacional de Catalunya, Barcelona, Spain.; PhD Program in Biotechnology, Faculty of Pharmacy and Food Sciences, University of Barcelona, Barcelona, Spain., Puerta R; Ace Alzheimer Center Barcelona - Universitat Internacional de Catalunya, Barcelona, Spain.; PhD Program in Biotechnology, Faculty of Pharmacy and Food Sciences, University of Barcelona, Barcelona, Spain., Olivé C; Ace Alzheimer Center Barcelona - Universitat Internacional de Catalunya, Barcelona, Spain.; PhD Program in Biotechnology, Faculty of Pharmacy and Food Sciences, University of Barcelona, Barcelona, Spain., Capdevila-Bayo M; Ace Alzheimer Center Barcelona - Universitat Internacional de Catalunya, Barcelona, Spain.; Department of Pharmacology, Toxicology and Therapeutic Chemistry, Faculty of Pharmacy and Food Science, University of Barcelona, Barcelona, Spain., Muñoz-Morales Á; Ace Alzheimer Center Barcelona - Universitat Internacional de Catalunya, Barcelona, Spain., Bayón-Buján P; Ace Alzheimer Center Barcelona - Universitat Internacional de Catalunya, Barcelona, Spain., Montrreal L; Ace Alzheimer Center Barcelona - Universitat Internacional de Catalunya, Barcelona, Spain., Orellana A; Ace Alzheimer Center Barcelona - Universitat Internacional de Catalunya, Barcelona, Spain.; Networking Research Center on Neurodegenerative Diseases (CIBERNED), Instituto de Salud Carlos III, Madrid, Spain., Ortega G; Ace Alzheimer Center Barcelona - Universitat Internacional de Catalunya, Barcelona, Spain.; Networking Research Center on Neurodegenerative Diseases (CIBERNED), Instituto de Salud Carlos III, Madrid, Spain., Sanz-Cartagena P; Ace Alzheimer Center Barcelona - Universitat Internacional de Catalunya, Barcelona, Spain., Rosende-Roca M; Ace Alzheimer Center Barcelona - Universitat Internacional de Catalunya, Barcelona, Spain., Cantero-Fortiz Y; Ace Alzheimer Center Barcelona - Universitat Internacional de Catalunya, Barcelona, Spain.; Networking Research Center on Neurodegenerative Diseases (CIBERNED), Instituto de Salud Carlos III, Madrid, Spain., Gurruchaga MJ; Ace Alzheimer Center Barcelona - Universitat Internacional de Catalunya, Barcelona, Spain., Tarraga L; Ace Alzheimer Center Barcelona - Universitat Internacional de Catalunya, Barcelona, Spain.; Networking Research Center on Neurodegenerative Diseases (CIBERNED), Instituto de Salud Carlos III, Madrid, Spain., Butler C; Ace Alzheimer Center Barcelona - Universitat Internacional de Catalunya, Barcelona, Spain.; Department of Brain Sciences, Imperial College London, London, United Kingdom.; The George Institute for Global Health, School of Public Health, Imperial College London, London, United Kingdom., Montalban X; Ace Alzheimer Center Barcelona - Universitat Internacional de Catalunya, Barcelona, Spain.; Networking Research Center on Neurodegenerative Diseases (CIBERNED), Instituto de Salud Carlos III, Madrid, Spain.; Department of Neurology and Multiple Sclerosis Center of Catalonia (Cemcat), Vall d'Hebron University Hospital, Universitat Autònoma de Barcelona (UAB), Barcelona, Spain., Boada M; Ace Alzheimer Center Barcelona - Universitat Internacional de Catalunya, Barcelona, Spain.; Networking Research Center on Neurodegenerative Diseases (CIBERNED), Instituto de Salud Carlos III, Madrid, Spain., Ruiz A; Ace Alzheimer Center Barcelona - Universitat Internacional de Catalunya, Barcelona, Spain.; Networking Research Center on Neurodegenerative Diseases (CIBERNED), Instituto de Salud Carlos III, Madrid, Spain.; Glenn Biggs Institute for Alzheimer's and Neurodegenerative Diseases, University of Texas Health Science Center, San Antonio, TX, United States.; Department of Microbiology, Immunology and Molecular Genetics, Long School of Medicine, University of Texas Health Science Center, San Antonio, TX, United States., Marquié M; Ace Alzheimer Center Barcelona - Universitat Internacional de Catalunya, Barcelona, Spain.; Networking Research Center on Neurodegenerative Diseases (CIBERNED), Instituto de Salud Carlos III, Madrid, Spain., Valero S; Ace Alzheimer Center Barcelona - Universitat Internacional de Catalunya, Barcelona, Spain.; Networking Research Center on Neurodegenerative Diseases (CIBERNED), Instituto de Salud Carlos III, Madrid, Spain.
Source: Frontiers in aging neuroscience [Front Aging Neurosci] 2026 May 04; Vol. 18, pp. 1816747. Date of Electronic Publication: 2026 May 04 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Research Foundation Country of Publication: Switzerland NLM ID: 101525824 Publication Model: eCollection Cited Medium: Print ISSN: 1663-4365 (Print) Linking ISSN: 16634365 NLM ISO Abbreviation: Front Aging Neurosci Subsets: PubMed not MEDLINE
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  Data: Listening for Alzheimer's clues: machine learning analysis of multidomain speech features for cognitive impairment screening.
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  Data: <searchLink fieldCode="AU" term="%22Blazquez-Folch+J%22">Blazquez-Folch J</searchLink>; Ace Alzheimer Center Barcelona - Universitat Internacional de Catalunya, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Calm+B%22">Calm B</searchLink>; Ace Alzheimer Center Barcelona - Universitat Internacional de Catalunya, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Hinojosa-Calleja+A%22">Hinojosa-Calleja A</searchLink>; Ace Alzheimer Center Barcelona - Universitat Internacional de Catalunya, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22García-Gutiérrez+F%22">García-Gutiérrez F</searchLink>; Ace Alzheimer Center Barcelona - Universitat Internacional de Catalunya, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Alegret+M%22">Alegret M</searchLink>; Ace Alzheimer Center Barcelona - Universitat Internacional de Catalunya, Barcelona, Spain.; Networking Research Center on Neurodegenerative Diseases (CIBERNED), Instituto de Salud Carlos III, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Muñoz+N%22">Muñoz N</searchLink>; Ace Alzheimer Center Barcelona - Universitat Internacional de Catalunya, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Cano+A%22">Cano A</searchLink>; Ace Alzheimer Center Barcelona - Universitat Internacional de Catalunya, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Fernández+MV%22">Fernández MV</searchLink>; Ace Alzheimer Center Barcelona - Universitat Internacional de Catalunya, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Miguel+A%22">Miguel A</searchLink>; Ace Alzheimer Center Barcelona - Universitat Internacional de Catalunya, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Solivar+A%22">Solivar A</searchLink>; Ace Alzheimer Center Barcelona - Universitat Internacional de Catalunya, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22De+Rojas+I%22">De Rojas I</searchLink>; Ace Alzheimer Center Barcelona - Universitat Internacional de Catalunya, Barcelona, Spain.; Networking Research Center on Neurodegenerative Diseases (CIBERNED), Instituto de Salud Carlos III, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Valenzuela-Seba+A%22">Valenzuela-Seba A</searchLink>; Ace Alzheimer Center Barcelona - Universitat Internacional de Catalunya, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22García-González+P%22">García-González P</searchLink>; Ace Alzheimer Center Barcelona - Universitat Internacional de Catalunya, Barcelona, Spain.; PhD Program in Biotechnology, Faculty of Pharmacy and Food Sciences, University of Barcelona, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Puerta+R%22">Puerta R</searchLink>; Ace Alzheimer Center Barcelona - Universitat Internacional de Catalunya, Barcelona, Spain.; PhD Program in Biotechnology, Faculty of Pharmacy and Food Sciences, University of Barcelona, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Olivé+C%22">Olivé C</searchLink>; Ace Alzheimer Center Barcelona - Universitat Internacional de Catalunya, Barcelona, Spain.; PhD Program in Biotechnology, Faculty of Pharmacy and Food Sciences, University of Barcelona, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Capdevila-Bayo+M%22">Capdevila-Bayo M</searchLink>; Ace Alzheimer Center Barcelona - Universitat Internacional de Catalunya, Barcelona, Spain.; Department of Pharmacology, Toxicology and Therapeutic Chemistry, Faculty of Pharmacy and Food Science, University of Barcelona, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Muñoz-Morales+Á%22">Muñoz-Morales Á</searchLink>; Ace Alzheimer Center Barcelona - Universitat Internacional de Catalunya, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Bayón-Buján+P%22">Bayón-Buján P</searchLink>; Ace Alzheimer Center Barcelona - Universitat Internacional de Catalunya, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Montrreal+L%22">Montrreal L</searchLink>; Ace Alzheimer Center Barcelona - Universitat Internacional de Catalunya, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Orellana+A%22">Orellana A</searchLink>; Ace Alzheimer Center Barcelona - Universitat Internacional de Catalunya, Barcelona, Spain.; Networking Research Center on Neurodegenerative Diseases (CIBERNED), Instituto de Salud Carlos III, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Ortega+G%22">Ortega G</searchLink>; Ace Alzheimer Center Barcelona - Universitat Internacional de Catalunya, Barcelona, Spain.; Networking Research Center on Neurodegenerative Diseases (CIBERNED), Instituto de Salud Carlos III, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Sanz-Cartagena+P%22">Sanz-Cartagena P</searchLink>; Ace Alzheimer Center Barcelona - Universitat Internacional de Catalunya, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Rosende-Roca+M%22">Rosende-Roca M</searchLink>; Ace Alzheimer Center Barcelona - Universitat Internacional de Catalunya, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Cantero-Fortiz+Y%22">Cantero-Fortiz Y</searchLink>; Ace Alzheimer Center Barcelona - Universitat Internacional de Catalunya, Barcelona, Spain.; Networking Research Center on Neurodegenerative Diseases (CIBERNED), Instituto de Salud Carlos III, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Gurruchaga+MJ%22">Gurruchaga MJ</searchLink>; Ace Alzheimer Center Barcelona - Universitat Internacional de Catalunya, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Tarraga+L%22">Tarraga L</searchLink>; Ace Alzheimer Center Barcelona - Universitat Internacional de Catalunya, Barcelona, Spain.; Networking Research Center on Neurodegenerative Diseases (CIBERNED), Instituto de Salud Carlos III, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Butler+C%22">Butler C</searchLink>; Ace Alzheimer Center Barcelona - Universitat Internacional de Catalunya, Barcelona, Spain.; Department of Brain Sciences, Imperial College London, London, United Kingdom.; The George Institute for Global Health, School of Public Health, Imperial College London, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Montalban+X%22">Montalban X</searchLink>; Ace Alzheimer Center Barcelona - Universitat Internacional de Catalunya, Barcelona, Spain.; Networking Research Center on Neurodegenerative Diseases (CIBERNED), Instituto de Salud Carlos III, Madrid, Spain.; Department of Neurology and Multiple Sclerosis Center of Catalonia (Cemcat), Vall d'Hebron University Hospital, Universitat Autònoma de Barcelona (UAB), Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Boada+M%22">Boada M</searchLink>; Ace Alzheimer Center Barcelona - Universitat Internacional de Catalunya, Barcelona, Spain.; Networking Research Center on Neurodegenerative Diseases (CIBERNED), Instituto de Salud Carlos III, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Ruiz+A%22">Ruiz A</searchLink>; Ace Alzheimer Center Barcelona - Universitat Internacional de Catalunya, Barcelona, Spain.; Networking Research Center on Neurodegenerative Diseases (CIBERNED), Instituto de Salud Carlos III, Madrid, Spain.; Glenn Biggs Institute for Alzheimer's and Neurodegenerative Diseases, University of Texas Health Science Center, San Antonio, TX, United States.; Department of Microbiology, Immunology and Molecular Genetics, Long School of Medicine, University of Texas Health Science Center, San Antonio, TX, United States.<br /><searchLink fieldCode="AU" term="%22Marquié+M%22">Marquié M</searchLink>; Ace Alzheimer Center Barcelona - Universitat Internacional de Catalunya, Barcelona, Spain.; Networking Research Center on Neurodegenerative Diseases (CIBERNED), Instituto de Salud Carlos III, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Valero+S%22">Valero S</searchLink>; Ace Alzheimer Center Barcelona - Universitat Internacional de Catalunya, Barcelona, Spain.; Networking Research Center on Neurodegenerative Diseases (CIBERNED), Instituto de Salud Carlos III, Madrid, Spain.
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