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GPX4 regulates lipid peroxidation and ferroptosis of stored red blood cells.

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Title: GPX4 regulates lipid peroxidation and ferroptosis of stored red blood cells.
Authors: Stephenson D; Department of Biochemistry and Molecular Genetics, University of Colorado Denver - Anschutz Medical Campus, Aurora, CO, USA., Keele GR; The Jackson Laboratory, Bar Harbor, ME, 04609, USA.; RTI International, Research Triangle Park, NC, USA., Hay A; University of Virginia, Charlottesville, VA, USA., Dzieciatkowska M; Department of Biochemistry and Molecular Genetics, University of Colorado Denver - Anschutz Medical Campus, Aurora, CO, USA., Reisz JA; Department of Biochemistry and Molecular Genetics, University of Colorado Denver - Anschutz Medical Campus, Aurora, CO, USA., Haiman ZB; Department of Biochemistry and Molecular Genetics, University of Colorado Denver - Anschutz Medical Campus, Aurora, CO, USA., Moore AL; RTI International, Research Triangle Park, NC, USA., Nemkov T; Department of Biochemistry and Molecular Genetics, University of Colorado Denver - Anschutz Medical Campus, Aurora, CO, USA.; Omix Technologies Inc, Aurora, CO, USA., Deng X; Vitalant Research Institute, San Francisco CA, USA.; Department of Laboratory Medicine, University of California San Francisco, CA, USA., Stone M; Vitalant Research Institute, San Francisco CA, USA.; Department of Laboratory Medicine, University of California San Francisco, CA, USA., Hansen KC; Department of Biochemistry and Molecular Genetics, University of Colorado Denver - Anschutz Medical Campus, Aurora, CO, USA., Kleinman S; University of British Columbia, Victoria, British Columbia, Canada., Norris PJ; Vitalant Research Institute, San Francisco CA, USA.; Department of Laboratory Medicine, University of California San Francisco, CA, USA., Busch MP; Vitalant Research Institute, San Francisco CA, USA.; Department of Laboratory Medicine, University of California San Francisco, CA, USA., Churchill GA; The Jackson Laboratory, Bar Harbor, ME, 04609, USA., Stockwell BR; Department of Biological Sciences, Department of Chemistry, and Department of Pathology and Cell Biology, Herbert Irving Comprehensive Cancer Center, Irving Institute for Cancer Dynamics, Digestive and Liver Disease Research Center, Columbia University, New York, NY 10027., Roubinian N; Vitalant Research Institute, San Francisco CA, USA.; Department of Laboratory Medicine, University of California San Francisco, CA, USA.; Kaiser Permanente Northern California Division of Research, Oakland, CA., Zimring JC; University of Virginia, Charlottesville, VA, USA., Page GP; RTI International, Research Triangle Park, NC, USA., D'Alessandro A; Department of Biochemistry and Molecular Genetics, University of Colorado Denver - Anschutz Medical Campus, Aurora, CO, USA.; Omix Technologies Inc, Aurora, CO, USA.
Source: Blood. Red cells & iron [Blood Red Cells Iron] 2025 Dec; Vol. 1 (3). Date of Electronic Publication: 2025 Sep 26.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier, Inc Country of Publication: United States NLM ID: 9919133140106676 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 3050-5984 (Electronic) Linking ISSN: 30505984 NLM ISO Abbreviation: Blood Red Cells Iron Subsets: PubMed not MEDLINE
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  Data: GPX4 regulates lipid peroxidation and ferroptosis of stored red blood cells.
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  Data: <searchLink fieldCode="AU" term="%22Stephenson+D%22">Stephenson D</searchLink>; Department of Biochemistry and Molecular Genetics, University of Colorado Denver - Anschutz Medical Campus, Aurora, CO, USA.<br /><searchLink fieldCode="AU" term="%22Keele+GR%22">Keele GR</searchLink>; The Jackson Laboratory, Bar Harbor, ME, 04609, USA.; RTI International, Research Triangle Park, NC, USA.<br /><searchLink fieldCode="AU" term="%22Hay+A%22">Hay A</searchLink>; University of Virginia, Charlottesville, VA, USA.<br /><searchLink fieldCode="AU" term="%22Dzieciatkowska+M%22">Dzieciatkowska M</searchLink>; Department of Biochemistry and Molecular Genetics, University of Colorado Denver - Anschutz Medical Campus, Aurora, CO, USA.<br /><searchLink fieldCode="AU" term="%22Reisz+JA%22">Reisz JA</searchLink>; Department of Biochemistry and Molecular Genetics, University of Colorado Denver - Anschutz Medical Campus, Aurora, CO, USA.<br /><searchLink fieldCode="AU" term="%22Haiman+ZB%22">Haiman ZB</searchLink>; Department of Biochemistry and Molecular Genetics, University of Colorado Denver - Anschutz Medical Campus, Aurora, CO, USA.<br /><searchLink fieldCode="AU" term="%22Moore+AL%22">Moore AL</searchLink>; RTI International, Research Triangle Park, NC, USA.<br /><searchLink fieldCode="AU" term="%22Nemkov+T%22">Nemkov T</searchLink>; Department of Biochemistry and Molecular Genetics, University of Colorado Denver - Anschutz Medical Campus, Aurora, CO, USA.; Omix Technologies Inc, Aurora, CO, USA.<br /><searchLink fieldCode="AU" term="%22Deng+X%22">Deng X</searchLink>; Vitalant Research Institute, San Francisco CA, USA.; Department of Laboratory Medicine, University of California San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Stone+M%22">Stone M</searchLink>; Vitalant Research Institute, San Francisco CA, USA.; Department of Laboratory Medicine, University of California San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Hansen+KC%22">Hansen KC</searchLink>; Department of Biochemistry and Molecular Genetics, University of Colorado Denver - Anschutz Medical Campus, Aurora, CO, USA.<br /><searchLink fieldCode="AU" term="%22Kleinman+S%22">Kleinman S</searchLink>; University of British Columbia, Victoria, British Columbia, Canada.<br /><searchLink fieldCode="AU" term="%22Norris+PJ%22">Norris PJ</searchLink>; Vitalant Research Institute, San Francisco CA, USA.; Department of Laboratory Medicine, University of California San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Busch+MP%22">Busch MP</searchLink>; Vitalant Research Institute, San Francisco CA, USA.; Department of Laboratory Medicine, University of California San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Churchill+GA%22">Churchill GA</searchLink>; The Jackson Laboratory, Bar Harbor, ME, 04609, USA.<br /><searchLink fieldCode="AU" term="%22Stockwell+BR%22">Stockwell BR</searchLink>; Department of Biological Sciences, Department of Chemistry, and Department of Pathology and Cell Biology, Herbert Irving Comprehensive Cancer Center, Irving Institute for Cancer Dynamics, Digestive and Liver Disease Research Center, Columbia University, New York, NY 10027.<br /><searchLink fieldCode="AU" term="%22Roubinian+N%22">Roubinian N</searchLink>; Vitalant Research Institute, San Francisco CA, USA.; Department of Laboratory Medicine, University of California San Francisco, CA, USA.; Kaiser Permanente Northern California Division of Research, Oakland, CA.<br /><searchLink fieldCode="AU" term="%22Zimring+JC%22">Zimring JC</searchLink>; University of Virginia, Charlottesville, VA, USA.<br /><searchLink fieldCode="AU" term="%22Page+GP%22">Page GP</searchLink>; RTI International, Research Triangle Park, NC, USA.<br /><searchLink fieldCode="AU" term="%22D'Alessandro+A%22">D'Alessandro A</searchLink>; Department of Biochemistry and Molecular Genetics, University of Colorado Denver - Anschutz Medical Campus, Aurora, CO, USA.; Omix Technologies Inc, Aurora, CO, USA.
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  Data: <searchLink fieldCode="JN" term="%229919133140106676%22">Blood. Red cells & iron</searchLink> [Blood Red Cells Iron] 2025 Dec; Vol. 1 (3). <i>Date of Electronic Publication: </i>2025 Sep 26.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%2C+Inc%22">Elsevier, Inc </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>9919133140106676 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>3050-5984 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2230505984%22">30505984 </searchLink><i>NLM ISO Abbreviation: </i>Blood Red Cells Iron <i>Subsets: </i>PubMed not MEDLINE
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              Text: 2025 Dec
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