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External Validation, Molecular Signatures, and Therapeutic Relevance of Pediatric Sepsis-Associated Acute Kidney Injury Subphenotypes.

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Title: External Validation, Molecular Signatures, and Therapeutic Relevance of Pediatric Sepsis-Associated Acute Kidney Injury Subphenotypes.
Authors: Stanski NL; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH.; Division of Critical Care Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH., Zhang B; Division of Biostatistics and Epidemiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH., Ouyang J; Division of Biostatistics and Epidemiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH., Standage SW; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH.; Division of Critical Care Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH., Cvijanovich NZ; Division of Critical Care Medicine, UCSF Benioff Children's Hospital Oakland, Oakland, CA., Fitzgerald JC; Division of Critical Care Medicine, Children's Hospital of Philadelphia, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA., Bigham MT; Division of Critical Care Medicine, Akron Children's Hospital, Akron, OH., Jain PN; Divisions of Pediatric Cardiology and Critical Care, Children's Medical Center and UT Southwestern Medical Center, Dallas, TX., Lutfi R; Division of Critical Care Medicine, Riley Hospital for Children, Indianapolis, IN., Allen GL; Division of Critical Care Medicine, Children's Mercy Hospital, Kansas City, MO., Thomas NJ; Division of Critical Care Medicine, Penn State Hershey Children's Hospital, Hershey, PA., Baines T; Division of Critical Care Medicine, University of Florida, Health Shands Children's Hospital, Gainesville, FL., Haileselassie B; Division of Critical Care Medicine, Lucile Packard Children's Hospital Stanford, Palo Alto, CA., Weiss SL; Division of Critical Care Medicine, Nemours Children's Hospital, Wilmington, DE.; Division of Critical Care Medicine, Sidney Kimmel Medical Center at Thomas Jefferson University, Philadelphia, PA., Lautz AJ; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH.; Division of Critical Care Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH., Kaplan JM; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH.; Division of Critical Care Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH., Zingarelli B; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH.; Division of Critical Care Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH., Atreya MR; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH.; Division of Critical Care Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH., Sanchez-Pinto LN; Division of Critical Care Medicine, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL., Goldstein SL; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH.; Division of Nephrology and Hypertension, Cincinnati Children's Hospital Medical Center, Cincinnati, OH., Liu KD; Department of Medicine, University of California San Francisco Medical Center, San Francisco, CA.
Source: Critical care medicine [Crit Care Med] 2026 Jul 01; Vol. 54 (7), pp. 1680-1690. Date of Electronic Publication: 2026 Mar 30.
Publication Type: Journal Article; Multicenter Study; Observational Study
Journal Info: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 0355501 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1530-0293 (Electronic) Linking ISSN: 00903493 NLM ISO Abbreviation: Crit Care Med Subsets: MEDLINE
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  Data: External Validation, Molecular Signatures, and Therapeutic Relevance of Pediatric Sepsis-Associated Acute Kidney Injury Subphenotypes.
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  Data: <searchLink fieldCode="AU" term="%22Stanski+NL%22">Stanski NL</searchLink>; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH.; Division of Critical Care Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH.<br /><searchLink fieldCode="AU" term="%22Zhang+B%22">Zhang B</searchLink>; Division of Biostatistics and Epidemiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH.<br /><searchLink fieldCode="AU" term="%22Ouyang+J%22">Ouyang J</searchLink>; Division of Biostatistics and Epidemiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH.<br /><searchLink fieldCode="AU" term="%22Standage+SW%22">Standage SW</searchLink>; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH.; Division of Critical Care Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH.<br /><searchLink fieldCode="AU" term="%22Cvijanovich+NZ%22">Cvijanovich NZ</searchLink>; Division of Critical Care Medicine, UCSF Benioff Children's Hospital Oakland, Oakland, CA.<br /><searchLink fieldCode="AU" term="%22Fitzgerald+JC%22">Fitzgerald JC</searchLink>; Division of Critical Care Medicine, Children's Hospital of Philadelphia, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA.<br /><searchLink fieldCode="AU" term="%22Bigham+MT%22">Bigham MT</searchLink>; Division of Critical Care Medicine, Akron Children's Hospital, Akron, OH.<br /><searchLink fieldCode="AU" term="%22Jain+PN%22">Jain PN</searchLink>; Divisions of Pediatric Cardiology and Critical Care, Children's Medical Center and UT Southwestern Medical Center, Dallas, TX.<br /><searchLink fieldCode="AU" term="%22Lutfi+R%22">Lutfi R</searchLink>; Division of Critical Care Medicine, Riley Hospital for Children, Indianapolis, IN.<br /><searchLink fieldCode="AU" term="%22Allen+GL%22">Allen GL</searchLink>; Division of Critical Care Medicine, Children's Mercy Hospital, Kansas City, MO.<br /><searchLink fieldCode="AU" term="%22Thomas+NJ%22">Thomas NJ</searchLink>; Division of Critical Care Medicine, Penn State Hershey Children's Hospital, Hershey, PA.<br /><searchLink fieldCode="AU" term="%22Baines+T%22">Baines T</searchLink>; Division of Critical Care Medicine, University of Florida, Health Shands Children's Hospital, Gainesville, FL.<br /><searchLink fieldCode="AU" term="%22Haileselassie+B%22">Haileselassie B</searchLink>; Division of Critical Care Medicine, Lucile Packard Children's Hospital Stanford, Palo Alto, CA.<br /><searchLink fieldCode="AU" term="%22Weiss+SL%22">Weiss SL</searchLink>; Division of Critical Care Medicine, Nemours Children's Hospital, Wilmington, DE.; Division of Critical Care Medicine, Sidney Kimmel Medical Center at Thomas Jefferson University, Philadelphia, PA.<br /><searchLink fieldCode="AU" term="%22Lautz+AJ%22">Lautz AJ</searchLink>; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH.; Division of Critical Care Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH.<br /><searchLink fieldCode="AU" term="%22Kaplan+JM%22">Kaplan JM</searchLink>; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH.; Division of Critical Care Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH.<br /><searchLink fieldCode="AU" term="%22Zingarelli+B%22">Zingarelli B</searchLink>; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH.; Division of Critical Care Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH.<br /><searchLink fieldCode="AU" term="%22Atreya+MR%22">Atreya MR</searchLink>; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH.; Division of Critical Care Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH.<br /><searchLink fieldCode="AU" term="%22Sanchez-Pinto+LN%22">Sanchez-Pinto LN</searchLink>; Division of Critical Care Medicine, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL.<br /><searchLink fieldCode="AU" term="%22Goldstein+SL%22">Goldstein SL</searchLink>; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH.; Division of Nephrology and Hypertension, Cincinnati Children's Hospital Medical Center, Cincinnati, OH.<br /><searchLink fieldCode="AU" term="%22Liu+KD%22">Liu KD</searchLink>; Department of Medicine, University of California San Francisco Medical Center, San Francisco, CA.
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  Data: <searchLink fieldCode="JN" term="%220355501%22">Critical care medicine</searchLink> [Crit Care Med] 2026 Jul 01; Vol. 54 (7), pp. 1680-1690. <i>Date of Electronic Publication: </i>2026 Mar 30.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Lippincott+Williams+%26+Wilkins%22">Lippincott Williams & Wilkins </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>0355501 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1530-0293 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200903493%22">00903493 </searchLink><i>NLM ISO Abbreviation: </i>Crit Care Med <i>Subsets: </i>MEDLINE
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