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Mediation pathways and complementary roles of DTI-ALPS and free water fraction in glymphatic impairment and cognitive decline.

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Title: Mediation pathways and complementary roles of DTI-ALPS and free water fraction in glymphatic impairment and cognitive decline.
Authors: Wei YC; Department of Neurology, Chang Gung Memorial Hospital, Keelung, Taiwan.; Community Medicine Research Center, Chang Gung Memorial Hospital, Keelung, Taiwan.; College of Medicine, Chang Gung University, Taoyuan, Taiwan.; College of Intelligent Computing, Chang Gung University, Taoyuan, Taiwan., Huang WY; Department of Neurology, Chang Gung Memorial Hospital, Keelung, Taiwan.; College of Medicine, Chang Gung University, Taoyuan, Taiwan., Lin C; Community Medicine Research Center, Chang Gung Memorial Hospital, Keelung, Taiwan.; College of Medicine, Chang Gung University, Taoyuan, Taiwan.; Department of Psychiatry, Chang Gung Memorial Hospital, Keelung, Taiwan., Chen CK; Community Medicine Research Center, Chang Gung Memorial Hospital, Keelung, Taiwan.; College of Medicine, Chang Gung University, Taoyuan, Taiwan.; Department of Psychiatry, Chang Gung Memorial Hospital, Keelung, Taiwan., Hsu CH; Institute of Neuroscience, National Yang Ming Chiao Tung University, Taipei, Taiwan., Ding CM; Institute of Neuroscience, National Yang Ming Chiao Tung University, Taipei, Taiwan., Chen YL; Department of Radiology, Chang Gung Memorial Hospital, Keelung, Taiwan.; Department of Medical Imaging and Radiological Sciences, Chang Gung University, Taoyuan, Taiwan., Lin CP; Institute of Neuroscience, National Yang Ming Chiao Tung University, Taipei, Taiwan.; Department of Education and Research, Taipei City Hospital, Taipei, Taiwan.
Source: Journal of Alzheimer's disease : JAD [J Alzheimers Dis] 2026 Jul; Vol. 112 (2), pp. 886-898. Date of Electronic Publication: 2026 May 20.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: SAGE Publications Country of Publication: United States NLM ID: 9814863 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1875-8908 (Electronic) Linking ISSN: 13872877 NLM ISO Abbreviation: J Alzheimers Dis Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Mediation pathways and complementary roles of DTI-ALPS and free water fraction in glymphatic impairment and cognitive decline.
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  Data: <searchLink fieldCode="AU" term="%22Wei+YC%22">Wei YC</searchLink>; Department of Neurology, Chang Gung Memorial Hospital, Keelung, Taiwan.; Community Medicine Research Center, Chang Gung Memorial Hospital, Keelung, Taiwan.; College of Medicine, Chang Gung University, Taoyuan, Taiwan.; College of Intelligent Computing, Chang Gung University, Taoyuan, Taiwan.<br /><searchLink fieldCode="AU" term="%22Huang+WY%22">Huang WY</searchLink>; Department of Neurology, Chang Gung Memorial Hospital, Keelung, Taiwan.; College of Medicine, Chang Gung University, Taoyuan, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lin+C%22">Lin C</searchLink>; Community Medicine Research Center, Chang Gung Memorial Hospital, Keelung, Taiwan.; College of Medicine, Chang Gung University, Taoyuan, Taiwan.; Department of Psychiatry, Chang Gung Memorial Hospital, Keelung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chen+CK%22">Chen CK</searchLink>; Community Medicine Research Center, Chang Gung Memorial Hospital, Keelung, Taiwan.; College of Medicine, Chang Gung University, Taoyuan, Taiwan.; Department of Psychiatry, Chang Gung Memorial Hospital, Keelung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Hsu+CH%22">Hsu CH</searchLink>; Institute of Neuroscience, National Yang Ming Chiao Tung University, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Ding+CM%22">Ding CM</searchLink>; Institute of Neuroscience, National Yang Ming Chiao Tung University, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chen+YL%22">Chen YL</searchLink>; Department of Radiology, Chang Gung Memorial Hospital, Keelung, Taiwan.; Department of Medical Imaging and Radiological Sciences, Chang Gung University, Taoyuan, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lin+CP%22">Lin CP</searchLink>; Institute of Neuroscience, National Yang Ming Chiao Tung University, Taipei, Taiwan.; Department of Education and Research, Taipei City Hospital, Taipei, Taiwan.
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  Data: <searchLink fieldCode="JN" term="%229814863%22">Journal of Alzheimer's disease : JAD</searchLink> [J Alzheimers Dis] 2026 Jul; Vol. 112 (2), pp. 886-898. <i>Date of Electronic Publication: </i>2026 May 20.
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  Data: Journal Article; Research Support, Non-U.S. Gov't
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22SAGE+Publications%22">SAGE Publications </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>9814863 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1875-8908 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2213872877%22">13872877 </searchLink><i>NLM ISO Abbreviation: </i>J Alzheimers Dis <i>Subsets: </i>MEDLINE
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      – Type: doi
        Value: 10.1177/13872877261447822
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      – Code: eng
        Text: English
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      – TitleFull: Mediation pathways and complementary roles of DTI-ALPS and free water fraction in glymphatic impairment and cognitive decline.
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            NameFull: Wei YC
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            – D: 01
              M: 07
              Text: 2026 Jul
              Type: published
              Y: 2026
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