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The Role of HGF/c-Met/PI3K/AKT Pathway Regulated by α7-nAChR/β2-AR in Nicotine-Promoted Malignant Progression of Nonsmall Cell Lung Cancer A549 Cells.

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Title: The Role of HGF/c-Met/PI3K/AKT Pathway Regulated by α7-nAChR/β2-AR in Nicotine-Promoted Malignant Progression of Nonsmall Cell Lung Cancer A549 Cells.
Authors: Li Z; School of Public Health, Jiangxi Medical College, Nanchang University, No. 461 Ba Yi Avenue, Nanchang, Jiangxi 330006, P. R. of China.; Jiangxi Provincial Key Laboratory of Disease Prevention and Public Health, Nanchang University, No. 461 Ba Yi Avenue, Nanchang, Jiangxi 330006, P. R. of China.; Chongqing Research Institute of Nanchang University, Tai Bai Road, Tongnan, Chongqing 402679, P. R. of China., Xie B; School of Public Health, Jiangxi Medical College, Nanchang University, No. 461 Ba Yi Avenue, Nanchang, Jiangxi 330006, P. R. of China.; Jiangxi Provincial Key Laboratory of Disease Prevention and Public Health, Nanchang University, No. 461 Ba Yi Avenue, Nanchang, Jiangxi 330006, P. R. of China.; Chongqing Research Institute of Nanchang University, Tai Bai Road, Tongnan, Chongqing 402679, P. R. of China., Liu X; School of Public Health, Jiangxi Medical College, Nanchang University, No. 461 Ba Yi Avenue, Nanchang, Jiangxi 330006, P. R. of China.; Jiangxi Provincial Key Laboratory of Disease Prevention and Public Health, Nanchang University, No. 461 Ba Yi Avenue, Nanchang, Jiangxi 330006, P. R. of China.; Chongqing Research Institute of Nanchang University, Tai Bai Road, Tongnan, Chongqing 402679, P. R. of China., He Z; School of Public Health, Jiangxi Medical College, Nanchang University, No. 461 Ba Yi Avenue, Nanchang, Jiangxi 330006, P. R. of China.; Jiangxi Provincial Key Laboratory of Disease Prevention and Public Health, Nanchang University, No. 461 Ba Yi Avenue, Nanchang, Jiangxi 330006, P. R. of China.; Chongqing Research Institute of Nanchang University, Tai Bai Road, Tongnan, Chongqing 402679, P. R. of China., Zhang Z; School of Public Health, Jiangxi Medical College, Nanchang University, No. 461 Ba Yi Avenue, Nanchang, Jiangxi 330006, P. R. of China.; Jiangxi Provincial Key Laboratory of Disease Prevention and Public Health, Nanchang University, No. 461 Ba Yi Avenue, Nanchang, Jiangxi 330006, P. R. of China.; Chongqing Research Institute of Nanchang University, Tai Bai Road, Tongnan, Chongqing 402679, P. R. of China., Zhou J; School of Public Health, Jiangxi Medical College, Nanchang University, No. 461 Ba Yi Avenue, Nanchang, Jiangxi 330006, P. R. of China.; Jiangxi Provincial Key Laboratory of Disease Prevention and Public Health, Nanchang University, No. 461 Ba Yi Avenue, Nanchang, Jiangxi 330006, P. R. of China.; Chongqing Research Institute of Nanchang University, Tai Bai Road, Tongnan, Chongqing 402679, P. R. of China., Zhou T; School of Public Health, Jiangxi Medical College, Nanchang University, No. 461 Ba Yi Avenue, Nanchang, Jiangxi 330006, P. R. of China.; Jiangxi Provincial Key Laboratory of Disease Prevention and Public Health, Nanchang University, No. 461 Ba Yi Avenue, Nanchang, Jiangxi 330006, P. R. of China.; Chongqing Research Institute of Nanchang University, Tai Bai Road, Tongnan, Chongqing 402679, P. R. of China., Wang H; School of Public Health, Jiangxi Medical College, Nanchang University, No. 461 Ba Yi Avenue, Nanchang, Jiangxi 330006, P. R. of China.; Jiangxi Provincial Key Laboratory of Disease Prevention and Public Health, Nanchang University, No. 461 Ba Yi Avenue, Nanchang, Jiangxi 330006, P. R. of China.; Chongqing Research Institute of Nanchang University, Tai Bai Road, Tongnan, Chongqing 402679, P. R. of China.
Source: Chemical research in toxicology [Chem Res Toxicol] 2026 Jun 15; Vol. 39 (6), pp. 1088-1101. Date of Electronic Publication: 2026 May 20.
Publication Type: Journal Article
Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 8807448 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-5010 (Electronic) Linking ISSN: 0893228X NLM ISO Abbreviation: Chem Res Toxicol Subsets: MEDLINE
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  Data: The Role of HGF/c-Met/PI3K/AKT Pathway Regulated by α7-nAChR/β2-AR in Nicotine-Promoted Malignant Progression of Nonsmall Cell Lung Cancer A549 Cells.
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  Data: <searchLink fieldCode="AU" term="%22Li+Z%22">Li Z</searchLink>; School of Public Health, Jiangxi Medical College, Nanchang University, No. 461 Ba Yi Avenue, Nanchang, Jiangxi 330006, P. R. of China.; Jiangxi Provincial Key Laboratory of Disease Prevention and Public Health, Nanchang University, No. 461 Ba Yi Avenue, Nanchang, Jiangxi 330006, P. R. of China.; Chongqing Research Institute of Nanchang University, Tai Bai Road, Tongnan, Chongqing 402679, P. R. of China.<br /><searchLink fieldCode="AU" term="%22Xie+B%22">Xie B</searchLink>; School of Public Health, Jiangxi Medical College, Nanchang University, No. 461 Ba Yi Avenue, Nanchang, Jiangxi 330006, P. R. of China.; Jiangxi Provincial Key Laboratory of Disease Prevention and Public Health, Nanchang University, No. 461 Ba Yi Avenue, Nanchang, Jiangxi 330006, P. R. of China.; Chongqing Research Institute of Nanchang University, Tai Bai Road, Tongnan, Chongqing 402679, P. R. of China.<br /><searchLink fieldCode="AU" term="%22Liu+X%22">Liu X</searchLink>; School of Public Health, Jiangxi Medical College, Nanchang University, No. 461 Ba Yi Avenue, Nanchang, Jiangxi 330006, P. R. of China.; Jiangxi Provincial Key Laboratory of Disease Prevention and Public Health, Nanchang University, No. 461 Ba Yi Avenue, Nanchang, Jiangxi 330006, P. R. of China.; Chongqing Research Institute of Nanchang University, Tai Bai Road, Tongnan, Chongqing 402679, P. R. of China.<br /><searchLink fieldCode="AU" term="%22He+Z%22">He Z</searchLink>; School of Public Health, Jiangxi Medical College, Nanchang University, No. 461 Ba Yi Avenue, Nanchang, Jiangxi 330006, P. R. of China.; Jiangxi Provincial Key Laboratory of Disease Prevention and Public Health, Nanchang University, No. 461 Ba Yi Avenue, Nanchang, Jiangxi 330006, P. R. of China.; Chongqing Research Institute of Nanchang University, Tai Bai Road, Tongnan, Chongqing 402679, P. R. of China.<br /><searchLink fieldCode="AU" term="%22Zhang+Z%22">Zhang Z</searchLink>; School of Public Health, Jiangxi Medical College, Nanchang University, No. 461 Ba Yi Avenue, Nanchang, Jiangxi 330006, P. R. of China.; Jiangxi Provincial Key Laboratory of Disease Prevention and Public Health, Nanchang University, No. 461 Ba Yi Avenue, Nanchang, Jiangxi 330006, P. R. of China.; Chongqing Research Institute of Nanchang University, Tai Bai Road, Tongnan, Chongqing 402679, P. R. of China.<br /><searchLink fieldCode="AU" term="%22Zhou+J%22">Zhou J</searchLink>; School of Public Health, Jiangxi Medical College, Nanchang University, No. 461 Ba Yi Avenue, Nanchang, Jiangxi 330006, P. R. of China.; Jiangxi Provincial Key Laboratory of Disease Prevention and Public Health, Nanchang University, No. 461 Ba Yi Avenue, Nanchang, Jiangxi 330006, P. R. of China.; Chongqing Research Institute of Nanchang University, Tai Bai Road, Tongnan, Chongqing 402679, P. R. of China.<br /><searchLink fieldCode="AU" term="%22Zhou+T%22">Zhou T</searchLink>; School of Public Health, Jiangxi Medical College, Nanchang University, No. 461 Ba Yi Avenue, Nanchang, Jiangxi 330006, P. R. of China.; Jiangxi Provincial Key Laboratory of Disease Prevention and Public Health, Nanchang University, No. 461 Ba Yi Avenue, Nanchang, Jiangxi 330006, P. R. of China.; Chongqing Research Institute of Nanchang University, Tai Bai Road, Tongnan, Chongqing 402679, P. R. of China.<br /><searchLink fieldCode="AU" term="%22Wang+H%22">Wang H</searchLink>; School of Public Health, Jiangxi Medical College, Nanchang University, No. 461 Ba Yi Avenue, Nanchang, Jiangxi 330006, P. R. of China.; Jiangxi Provincial Key Laboratory of Disease Prevention and Public Health, Nanchang University, No. 461 Ba Yi Avenue, Nanchang, Jiangxi 330006, P. R. of China.; Chongqing Research Institute of Nanchang University, Tai Bai Road, Tongnan, Chongqing 402679, P. R. of China.
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  Data: <searchLink fieldCode="JN" term="%228807448%22">Chemical research in toxicology</searchLink> [Chem Res Toxicol] 2026 Jun 15; Vol. 39 (6), pp. 1088-1101. <i>Date of Electronic Publication: </i>2026 May 20.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Chemical+Society%22">American Chemical Society </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>8807448 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1520-5010 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%220893228X%22">0893228X </searchLink><i>NLM ISO Abbreviation: </i>Chem Res Toxicol <i>Subsets: </i>MEDLINE
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        Value: 10.1021/acs.chemrestox.5c00464
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        Text: English
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              Text: 2026 Jun 15
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