Identification of RET PROTAC with excellent degradation efficiency against medullary thyroid carcinoma.
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| Title: | Identification of RET PROTAC with excellent degradation efficiency against medullary thyroid carcinoma. |
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| Authors: | Song J; Department of Biomedical Sciences, Graduate School of Medical Science, Yonsei University College of Medicine, 50 Yonsei-ro, Seodaemun-gu, Seoul, 03722, Republic of Korea; Clinical Candidate Discovery & Development Institute, Yonsei University College of Medicine, 50 Yonsei-ro, Seodaemun-gu, Seoul, 03722, Republic of Korea., Lim S; Department of Biomedical Sciences, Graduate School of Medical Science, Yonsei University College of Medicine, 50 Yonsei-ro, Seodaemun-gu, Seoul, 03722, Republic of Korea; Clinical Candidate Discovery & Development Institute, Yonsei University College of Medicine, 50 Yonsei-ro, Seodaemun-gu, Seoul, 03722, Republic of Korea., Jeon E; Department of Biomedical Sciences, Graduate School of Medical Science, Yonsei University College of Medicine, 50 Yonsei-ro, Seodaemun-gu, Seoul, 03722, Republic of Korea; Department of Medical Science, Graduate School of Medical Science, Brain Korea 21 Project, Yonsei University College of Medicine, 50 Yonsei-ro, Seodaemun-gu, Seoul, 03722, Republic of Korea., Kim C; OmixAI Co., Ltd., 43 Janghan-ro, Dongdaemun-gu, Seoul, 02629, Republic of Korea., Park SM; Department of Medicine, Kyung Hee University School of Medicine, 26 Kyunghee-daero, Dongdaemun-gu, Seoul, 02447, Republic of Korea., Park JB; OmixAI Co., Ltd., 43 Janghan-ro, Dongdaemun-gu, Seoul, 02629, Republic of Korea; Department of Medicine, Kyung Hee University School of Medicine, 26 Kyunghee-daero, Dongdaemun-gu, Seoul, 02447, Republic of Korea., Sim T; Department of Biomedical Sciences, Graduate School of Medical Science, Yonsei University College of Medicine, 50 Yonsei-ro, Seodaemun-gu, Seoul, 03722, Republic of Korea; Clinical Candidate Discovery & Development Institute, Yonsei University College of Medicine, 50 Yonsei-ro, Seodaemun-gu, Seoul, 03722, Republic of Korea; Graduate School of Clinical Drug Discovery & Development, Yonsei University College of Medicine, 50 Yonsei-ro, Seodaemun-gu, Seoul, 03722, Republic of Korea; Department of Medical Science, Graduate School of Medical Science, Brain Korea 21 Project, Yonsei University College of Medicine, 50 Yonsei-ro, Seodaemun-gu, Seoul, 03722, Republic of Korea. Electronic address: TBSIM@yuhs.ac. |
| Source: | European journal of medicinal chemistry [Eur J Med Chem] 2026 Oct 05; Vol. 315, pp. 118928. Date of Electronic Publication: 2026 May 10. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 0420510 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1768-3254 (Electronic) Linking ISSN: 02235234 NLM ISO Abbreviation: Eur J Med Chem Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 42161102 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Identification of RET PROTAC with excellent degradation efficiency against medullary thyroid carcinoma. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Song+J%22">Song J</searchLink>; Department of Biomedical Sciences, Graduate School of Medical Science, Yonsei University College of Medicine, 50 Yonsei-ro, Seodaemun-gu, Seoul, 03722, Republic of Korea; Clinical Candidate Discovery & Development Institute, Yonsei University College of Medicine, 50 Yonsei-ro, Seodaemun-gu, Seoul, 03722, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Lim+S%22">Lim S</searchLink>; Department of Biomedical Sciences, Graduate School of Medical Science, Yonsei University College of Medicine, 50 Yonsei-ro, Seodaemun-gu, Seoul, 03722, Republic of Korea; Clinical Candidate Discovery & Development Institute, Yonsei University College of Medicine, 50 Yonsei-ro, Seodaemun-gu, Seoul, 03722, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Jeon+E%22">Jeon E</searchLink>; Department of Biomedical Sciences, Graduate School of Medical Science, Yonsei University College of Medicine, 50 Yonsei-ro, Seodaemun-gu, Seoul, 03722, Republic of Korea; Department of Medical Science, Graduate School of Medical Science, Brain Korea 21 Project, Yonsei University College of Medicine, 50 Yonsei-ro, Seodaemun-gu, Seoul, 03722, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+C%22">Kim C</searchLink>; OmixAI Co., Ltd., 43 Janghan-ro, Dongdaemun-gu, Seoul, 02629, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Park+SM%22">Park SM</searchLink>; Department of Medicine, Kyung Hee University School of Medicine, 26 Kyunghee-daero, Dongdaemun-gu, Seoul, 02447, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Park+JB%22">Park JB</searchLink>; OmixAI Co., Ltd., 43 Janghan-ro, Dongdaemun-gu, Seoul, 02629, Republic of Korea; Department of Medicine, Kyung Hee University School of Medicine, 26 Kyunghee-daero, Dongdaemun-gu, Seoul, 02447, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Sim+T%22">Sim T</searchLink>; Department of Biomedical Sciences, Graduate School of Medical Science, Yonsei University College of Medicine, 50 Yonsei-ro, Seodaemun-gu, Seoul, 03722, Republic of Korea; Clinical Candidate Discovery & Development Institute, Yonsei University College of Medicine, 50 Yonsei-ro, Seodaemun-gu, Seoul, 03722, Republic of Korea; Graduate School of Clinical Drug Discovery & Development, Yonsei University College of Medicine, 50 Yonsei-ro, Seodaemun-gu, Seoul, 03722, Republic of Korea; Department of Medical Science, Graduate School of Medical Science, Brain Korea 21 Project, Yonsei University College of Medicine, 50 Yonsei-ro, Seodaemun-gu, Seoul, 03722, Republic of Korea. Electronic address: TBSIM@yuhs.ac. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%220420510%22">European journal of medicinal chemistry</searchLink> [Eur J Med Chem] 2026 Oct 05; Vol. 315, pp. 118928. <i>Date of Electronic Publication: </i>2026 May 10. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Editions+Scientifiques+Elsevier%22">Editions Scientifiques Elsevier </searchLink><i>Country of Publication: </i>France <i>NLM ID: </i>0420510 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1768-3254 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2202235234%22">02235234 </searchLink><i>NLM ISO Abbreviation: </i>Eur J Med Chem <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=42161102 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1016/j.ejmech.2026.118928 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 118928 Titles: – TitleFull: Identification of RET PROTAC with excellent degradation efficiency against medullary thyroid carcinoma. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Song J – PersonEntity: Name: NameFull: Lim S – PersonEntity: Name: NameFull: Jeon E – PersonEntity: Name: NameFull: Kim C – PersonEntity: Name: NameFull: Park SM – PersonEntity: Name: NameFull: Park JB – PersonEntity: Name: NameFull: Sim T IsPartOfRelationships: – BibEntity: Dates: – D: 05 M: 10 Text: 2026 Oct 05 Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 1768-3254 Numbering: – Type: volume Value: 315 Titles: – TitleFull: European journal of medicinal chemistry Type: main |
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