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Nociceptive innervation limits tertiary lymphoid structures to promote lung cancer.

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Title: Nociceptive innervation limits tertiary lymphoid structures to promote lung cancer.
Authors: Ho YH; Cancer Neuroscience Laboratory, Francis Crick Institute, London NW1 1AT, UK., Bregni G; Cancer Neuroscience Laboratory, Francis Crick Institute, London NW1 1AT, UK., Stazi M; Cancer Neuroscience Laboratory, Francis Crick Institute, London NW1 1AT, UK., Peinado P; Cancer Neuroscience Laboratory, Francis Crick Institute, London NW1 1AT, UK., Chen PH; Division of Thoracic Surgery, Department of Surgery, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei 100225, Taiwan., Ballabio C; Cancer Neuroscience Laboratory, Francis Crick Institute, London NW1 1AT, UK., Boulat V; Immunity and Cancer Laboratory, Francis Crick Institute, London NW1 1AT, UK., Vadera S; Cancer Neuroscience Laboratory, Francis Crick Institute, London NW1 1AT, UK., Guan Y; Cancer Neuroscience Laboratory, Francis Crick Institute, London NW1 1AT, UK., Liu Z; Department of Cell Biology, Harvard Medical School, Boston, MA 02115, USA., Alonso de la Vega A; Oncogene Biology Laboratory, Francis Crick Institute, London NW1 1AT, UK., Wang L; Zuckerman Mind Brain Behavior Institute, Columbia University, New York, NY 10027, USA., Ho CC; Department of Internal Medicine, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei 100225, Taiwan., Veiga-Fernandes H; Immunophysiology Group, Champalimaud Foundation, Lisbon 1400-038, Portugal., Downward J; Oncogene Biology Laboratory, Francis Crick Institute, London NW1 1AT, UK., Hsieh MS; Department of Pathology, National Taiwan University Hospital, Taipei 10025, Taiwan., Kopanitsa MV; Cancer Neuroscience Laboratory, Francis Crick Institute, London NW1 1AT, UK., Kassiotis G; Retroviral Immunology Laboratory, Francis Crick Institute, London NW1 1AT, UK., Tsantoulas C; Cancer Neuroscience Laboratory, Francis Crick Institute, London NW1 1AT, UK., Schappe MS; Department of Cell Biology, Harvard Medical School, Boston, MA 02115, USA; Department of Molecular & Integrative Physiology, University of Illinois Urbana-Champaign, Urbana, IL 61801, USA., Margineanu MB; Cancer Neuroscience Laboratory, Francis Crick Institute, London NW1 1AT, UK; Center of Immuno-Physiology and Biotechnologies, Department of Functional Sciences, 'Victor Babes' University of Medicine and Pharmacy, Timisoara 300041, Romania., Calado DP; Immunity and Cancer Laboratory, Francis Crick Institute, London NW1 1AT, UK., Chiu IM; Department of Immunology, Harvard Medical School, Boston, MA 02115, USA., Swanton C; Cancer Evolution and Genome Instability Laboratory, Francis Crick Institute, London NW1 1AT, UK; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London WC1E 6DD, UK; Department of Oncology, University College London Hospitals, London WC1E 6AG, UK., Chen JS; Division of Thoracic Surgery, Department of Surgery, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei 100225, Taiwan., Li L; Cancer Neuroscience Laboratory, Francis Crick Institute, London NW1 1AT, UK. Electronic address: leanne.li@crick.ac.uk.
Source: Cell [Cell] 2026 Jul 09; Vol. 189 (14), pp. 4276-4294.e33. Date of Electronic Publication: 2026 May 19.
Publication Type: Journal Article
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 0413066 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-4172 (Electronic) Linking ISSN: 00928674 NLM ISO Abbreviation: Cell Subsets: MEDLINE
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  Data: Nociceptive innervation limits tertiary lymphoid structures to promote lung cancer.
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  Data: <searchLink fieldCode="AU" term="%22Ho+YH%22">Ho YH</searchLink>; Cancer Neuroscience Laboratory, Francis Crick Institute, London NW1 1AT, UK.<br /><searchLink fieldCode="AU" term="%22Bregni+G%22">Bregni G</searchLink>; Cancer Neuroscience Laboratory, Francis Crick Institute, London NW1 1AT, UK.<br /><searchLink fieldCode="AU" term="%22Stazi+M%22">Stazi M</searchLink>; Cancer Neuroscience Laboratory, Francis Crick Institute, London NW1 1AT, UK.<br /><searchLink fieldCode="AU" term="%22Peinado+P%22">Peinado P</searchLink>; Cancer Neuroscience Laboratory, Francis Crick Institute, London NW1 1AT, UK.<br /><searchLink fieldCode="AU" term="%22Chen+PH%22">Chen PH</searchLink>; Division of Thoracic Surgery, Department of Surgery, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei 100225, Taiwan.<br /><searchLink fieldCode="AU" term="%22Ballabio+C%22">Ballabio C</searchLink>; Cancer Neuroscience Laboratory, Francis Crick Institute, London NW1 1AT, UK.<br /><searchLink fieldCode="AU" term="%22Boulat+V%22">Boulat V</searchLink>; Immunity and Cancer Laboratory, Francis Crick Institute, London NW1 1AT, UK.<br /><searchLink fieldCode="AU" term="%22Vadera+S%22">Vadera S</searchLink>; Cancer Neuroscience Laboratory, Francis Crick Institute, London NW1 1AT, UK.<br /><searchLink fieldCode="AU" term="%22Guan+Y%22">Guan Y</searchLink>; Cancer Neuroscience Laboratory, Francis Crick Institute, London NW1 1AT, UK.<br /><searchLink fieldCode="AU" term="%22Liu+Z%22">Liu Z</searchLink>; Department of Cell Biology, Harvard Medical School, Boston, MA 02115, USA.<br /><searchLink fieldCode="AU" term="%22Alonso+de+la+Vega+A%22">Alonso de la Vega A</searchLink>; Oncogene Biology Laboratory, Francis Crick Institute, London NW1 1AT, UK.<br /><searchLink fieldCode="AU" term="%22Wang+L%22">Wang L</searchLink>; Zuckerman Mind Brain Behavior Institute, Columbia University, New York, NY 10027, USA.<br /><searchLink fieldCode="AU" term="%22Ho+CC%22">Ho CC</searchLink>; Department of Internal Medicine, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei 100225, Taiwan.<br /><searchLink fieldCode="AU" term="%22Veiga-Fernandes+H%22">Veiga-Fernandes H</searchLink>; Immunophysiology Group, Champalimaud Foundation, Lisbon 1400-038, Portugal.<br /><searchLink fieldCode="AU" term="%22Downward+J%22">Downward J</searchLink>; Oncogene Biology Laboratory, Francis Crick Institute, London NW1 1AT, UK.<br /><searchLink fieldCode="AU" term="%22Hsieh+MS%22">Hsieh MS</searchLink>; Department of Pathology, National Taiwan University Hospital, Taipei 10025, Taiwan.<br /><searchLink fieldCode="AU" term="%22Kopanitsa+MV%22">Kopanitsa MV</searchLink>; Cancer Neuroscience Laboratory, Francis Crick Institute, London NW1 1AT, UK.<br /><searchLink fieldCode="AU" term="%22Kassiotis+G%22">Kassiotis G</searchLink>; Retroviral Immunology Laboratory, Francis Crick Institute, London NW1 1AT, UK.<br /><searchLink fieldCode="AU" term="%22Tsantoulas+C%22">Tsantoulas C</searchLink>; Cancer Neuroscience Laboratory, Francis Crick Institute, London NW1 1AT, UK.<br /><searchLink fieldCode="AU" term="%22Schappe+MS%22">Schappe MS</searchLink>; Department of Cell Biology, Harvard Medical School, Boston, MA 02115, USA; Department of Molecular & Integrative Physiology, University of Illinois Urbana-Champaign, Urbana, IL 61801, USA.<br /><searchLink fieldCode="AU" term="%22Margineanu+MB%22">Margineanu MB</searchLink>; Cancer Neuroscience Laboratory, Francis Crick Institute, London NW1 1AT, UK; Center of Immuno-Physiology and Biotechnologies, Department of Functional Sciences, 'Victor Babes' University of Medicine and Pharmacy, Timisoara 300041, Romania.<br /><searchLink fieldCode="AU" term="%22Calado+DP%22">Calado DP</searchLink>; Immunity and Cancer Laboratory, Francis Crick Institute, London NW1 1AT, UK.<br /><searchLink fieldCode="AU" term="%22Chiu+IM%22">Chiu IM</searchLink>; Department of Immunology, Harvard Medical School, Boston, MA 02115, USA.<br /><searchLink fieldCode="AU" term="%22Swanton+C%22">Swanton C</searchLink>; Cancer Evolution and Genome Instability Laboratory, Francis Crick Institute, London NW1 1AT, UK; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London WC1E 6DD, UK; Department of Oncology, University College London Hospitals, London WC1E 6AG, UK.<br /><searchLink fieldCode="AU" term="%22Chen+JS%22">Chen JS</searchLink>; Division of Thoracic Surgery, Department of Surgery, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei 100225, Taiwan.<br /><searchLink fieldCode="AU" term="%22Li+L%22">Li L</searchLink>; Cancer Neuroscience Laboratory, Francis Crick Institute, London NW1 1AT, UK. Electronic address: leanne.li@crick.ac.uk.
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  Data: <searchLink fieldCode="JN" term="%220413066%22">Cell</searchLink> [Cell] 2026 Jul 09; Vol. 189 (14), pp. 4276-4294.e33. <i>Date of Electronic Publication: </i>2026 May 19.
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