Application of age- and sex-specific reference intervals for thyroid-stimulating hormone and free thyroxine in evaluating incidence and trends of thyroid dysfunctions: A population-based cohort study.

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Title: Application of age- and sex-specific reference intervals for thyroid-stimulating hormone and free thyroxine in evaluating incidence and trends of thyroid dysfunctions: A population-based cohort study.
Authors: Lu J; Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Hong Kong Special Administrative Region, China., Tang CM; Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Hong Kong Special Administrative Region, China., Ge GM; Department of Pharmacology and Pharmacy, The University of Hong Kong, Hong Kong Special Administrative Region, China., Cheng KK; Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Hong Kong Special Administrative Region, China., Lee KC; Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Hong Kong Special Administrative Region, China., Tan KC; Department of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region, China., Lam SK; The Nethersole School of Nursing, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China.; School of Nursing and Health Sciences, Hong Kong Metropolitan University, Hong Kong Special Administrative Region, China., Cheung EY; Hong Kong Institute of Diabetes and Obesity, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China., Cheung CL; Department of Pharmacology and Pharmacy, The University of Hong Kong, Hong Kong Special Administrative Region, China.; Hinda and Arthur Marcus Institute for Aging Research, Hebrew SeniorLife, Boston, MA, USA., Li GH; Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Hong Kong Special Administrative Region, China. gloria-hy.li@polyu.edu.hk.
Source: BMC medicine [BMC Med] 2026 May 20; Vol. 24 (1). Date of Electronic Publication: 2026 May 20.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101190723 Publication Model: Electronic Cited Medium: Internet ISSN: 1741-7015 (Electronic) Linking ISSN: 17417015 NLM ISO Abbreviation: BMC Med Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1741-7015
DOI:10.1186/s12916-026-04942-5