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A clinically feasible framework to estimate tau pathology and clinical-biological discordance in the Alzheimer's disease spectrum.

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Title: A clinically feasible framework to estimate tau pathology and clinical-biological discordance in the Alzheimer's disease spectrum.
Authors: Hsu JL; Department of Neurology, New Taipei Municipal TuCheng Hospital, New Taipei City, Taiwan.; Department of Neurology and Neuroscience Research Center, Linkou Chang Gung Memorial Hospital & College of Medicine, Chang Gung University, Taoyuan, Taiwan.; Graduate Institute of Humanities in Medicine, Taipei Medical University & Research Center for Brain and Consciousness, Shuang Ho Hospital, Taipei, Taiwan., Huang SY; Department of Medical Imaging and Radiological Sciences, College of Medicine & Healthy Aging Research Center, Chang Gung University, Taoyuan, Taiwan., Wu HC; Department of Neurology, Linkou Chang Gung Memorial Hospital & College of Medicine, Chang Gung University, Taoyuan, Taiwan., Lin KJ; Department of Medical Imaging and Radiological Sciences, College of Medicine & Healthy Aging Research Center, Chang Gung University, Taoyuan, Taiwan.; Department of Nuclear Medicine and Neuroscience Research Center, Linkou Chang Gung Memorial Hospital, Taoyuan, Taiwan., Huang KL; Department of Neurology, Linkou Chang Gung Memorial Hospital & College of Medicine, Chang Gung University, Taoyuan, Taiwan., Huang CC; Department of Neurology, Linkou Chang Gung Memorial Hospital & College of Medicine, Chang Gung University, Taoyuan, Taiwan., Kim S; Department of Neurology, Seoul National University College of Medicine & Clinical Neuroscience Center, Seoul National University Bundang Hospital, Seongnam, Republic of Korea., Hsiao IT; Department of Medical Imaging and Radiological Sciences, College of Medicine & Healthy Aging Research Center, Chang Gung University, Taoyuan, Taiwan. ihsiao@mail.cgu.edu.tw.; Department of Nuclear Medicine and Neuroscience Research Center, Linkou Chang Gung Memorial Hospital, Taoyuan, Taiwan. ihsiao@mail.cgu.edu.tw.
Source: Alzheimer's research & therapy [Alzheimers Res Ther] 2026 May 20; Vol. 18 (1). Date of Electronic Publication: 2026 May 20.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: BioMed Central Ltd Country of Publication: England NLM ID: 101511643 Publication Model: Electronic Cited Medium: Internet ISSN: 1758-9193 (Electronic) NLM ISO Abbreviation: Alzheimers Res Ther Subsets: MEDLINE
Database: MEDLINE Ultimate
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PubType: Academic Journal
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  Data: A clinically feasible framework to estimate tau pathology and clinical-biological discordance in the Alzheimer's disease spectrum.
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  Data: <searchLink fieldCode="AU" term="%22Hsu+JL%22">Hsu JL</searchLink>; Department of Neurology, New Taipei Municipal TuCheng Hospital, New Taipei City, Taiwan.; Department of Neurology and Neuroscience Research Center, Linkou Chang Gung Memorial Hospital & College of Medicine, Chang Gung University, Taoyuan, Taiwan.; Graduate Institute of Humanities in Medicine, Taipei Medical University & Research Center for Brain and Consciousness, Shuang Ho Hospital, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Huang+SY%22">Huang SY</searchLink>; Department of Medical Imaging and Radiological Sciences, College of Medicine & Healthy Aging Research Center, Chang Gung University, Taoyuan, Taiwan.<br /><searchLink fieldCode="AU" term="%22Wu+HC%22">Wu HC</searchLink>; Department of Neurology, Linkou Chang Gung Memorial Hospital & College of Medicine, Chang Gung University, Taoyuan, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lin+KJ%22">Lin KJ</searchLink>; Department of Medical Imaging and Radiological Sciences, College of Medicine & Healthy Aging Research Center, Chang Gung University, Taoyuan, Taiwan.; Department of Nuclear Medicine and Neuroscience Research Center, Linkou Chang Gung Memorial Hospital, Taoyuan, Taiwan.<br /><searchLink fieldCode="AU" term="%22Huang+KL%22">Huang KL</searchLink>; Department of Neurology, Linkou Chang Gung Memorial Hospital & College of Medicine, Chang Gung University, Taoyuan, Taiwan.<br /><searchLink fieldCode="AU" term="%22Huang+CC%22">Huang CC</searchLink>; Department of Neurology, Linkou Chang Gung Memorial Hospital & College of Medicine, Chang Gung University, Taoyuan, Taiwan.<br /><searchLink fieldCode="AU" term="%22Kim+S%22">Kim S</searchLink>; Department of Neurology, Seoul National University College of Medicine & Clinical Neuroscience Center, Seoul National University Bundang Hospital, Seongnam, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Hsiao+IT%22">Hsiao IT</searchLink>; Department of Medical Imaging and Radiological Sciences, College of Medicine & Healthy Aging Research Center, Chang Gung University, Taoyuan, Taiwan. ihsiao@mail.cgu.edu.tw.; Department of Nuclear Medicine and Neuroscience Research Center, Linkou Chang Gung Memorial Hospital, Taoyuan, Taiwan. ihsiao@mail.cgu.edu.tw.
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  Data: <searchLink fieldCode="JN" term="%22101511643%22">Alzheimer's research & therapy</searchLink> [Alzheimers Res Ther] 2026 May 20; Vol. 18 (1). <i>Date of Electronic Publication: </i>2026 May 20.
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  Data: Journal Article; Research Support, Non-U.S. Gov't
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central+Ltd%22">BioMed Central Ltd </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101511643 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1758-9193 (Electronic) <i>NLM ISO Abbreviation: </i>Alzheimers Res Ther <i>Subsets: </i>MEDLINE
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        Value: 10.1186/s13195-026-02083-8
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        Text: English
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              M: 05
              Text: 2026 May 20
              Type: published
              Y: 2026
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