The next phase in Long COVID research: addressing the ethical challenges in trials of disease-modifying treatments.

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Title: The next phase in Long COVID research: addressing the ethical challenges in trials of disease-modifying treatments.
Authors: Hendriks S; Department of Bioethics, Clinical Center, National Institutes of Health, Bethesda, MD, USA., Grady C; Department of Bioethics, Clinical Center, National Institutes of Health, Bethesda, MD, USA., Fitzgerald ML; Brain Inflammation Collaborative, Inc., Delafield, WI, USA.; Patient Led Research Collaborative, Calabasas, CA, USA., Gross RS; Division of General Pediatrics, Department of Pediatrics, Department of Population Health, NYU Grossman School of Medicine, New York, USA., Maughan C; Utah Covid-19 Long Haulers, Salt Lake City, UT, USA., Peluso MJ; Division of HIV, Infectious Diseases, and Global Medicine, University of California, San Francisco, San Francisco, CA, USA., Varma S; Independent Scholar., Nath A; Section of Infections of the Nervous System, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA., Rid A; Department of Bioethics, Clinical Center, National Institutes of Health, Bethesda, MD, USA.; Fogarty International Center, National Institutes of Health, Bethesda, MD, USA.
Source: EClinicalMedicine [EClinicalMedicine] 2026 May 07; Vol. 95, pp. 103918. Date of Electronic Publication: 2026 May 07 (Print Publication: 2026).
Publication Type: Journal Article; Review
Journal Info: Publisher: The Lancet Country of Publication: England NLM ID: 101733727 Publication Model: eCollection Cited Medium: Internet ISSN: 2589-5370 (Electronic) Linking ISSN: 25895370 NLM ISO Abbreviation: EClinicalMedicine Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Hendriks+S%22">Hendriks S</searchLink>; Department of Bioethics, Clinical Center, National Institutes of Health, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Grady+C%22">Grady C</searchLink>; Department of Bioethics, Clinical Center, National Institutes of Health, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Fitzgerald+ML%22">Fitzgerald ML</searchLink>; Brain Inflammation Collaborative, Inc., Delafield, WI, USA.; Patient Led Research Collaborative, Calabasas, CA, USA.<br /><searchLink fieldCode="AU" term="%22Gross+RS%22">Gross RS</searchLink>; Division of General Pediatrics, Department of Pediatrics, Department of Population Health, NYU Grossman School of Medicine, New York, USA.<br /><searchLink fieldCode="AU" term="%22Maughan+C%22">Maughan C</searchLink>; Utah Covid-19 Long Haulers, Salt Lake City, UT, USA.<br /><searchLink fieldCode="AU" term="%22Peluso+MJ%22">Peluso MJ</searchLink>; Division of HIV, Infectious Diseases, and Global Medicine, University of California, San Francisco, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Varma+S%22">Varma S</searchLink>; Independent Scholar.<br /><searchLink fieldCode="AU" term="%22Nath+A%22">Nath A</searchLink>; Section of Infections of the Nervous System, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Rid+A%22">Rid A</searchLink>; Department of Bioethics, Clinical Center, National Institutes of Health, Bethesda, MD, USA.; Fogarty International Center, National Institutes of Health, Bethesda, MD, USA.
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              Text: 2026 May 07
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