Efficacy and Safety of Fimasartan/Indapamide Combination Therapy versus Fimasartan Monotherapy in Patients with Essential Hypertension Inadequately Responding to Fimasartan 30 mg (FINEDUO): A Randomized, Double-Blind, Multicenter, Phase III Study.
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| Title: | Efficacy and Safety of Fimasartan/Indapamide Combination Therapy versus Fimasartan Monotherapy in Patients with Essential Hypertension Inadequately Responding to Fimasartan 30 mg (FINEDUO): A Randomized, Double-Blind, Multicenter, Phase III Study. |
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| Authors: | Youn JC; Department of Internal Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.; Catholic Research Institute for Intractable Cardiovascular Disease, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea., Lee SY; Department of Internal Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.; Catholic Research Institute for Intractable Cardiovascular Disease, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea., Yu CW; Department of Internal Medicine, Korea University Anam Hospital, Korea University College of Medicine, Seoul, Republic of Korea., Sung KC; Department of Internal Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea., Shin J; Department of Internal Medicine, Hanyang University Seoul Hospital, Hanyang University College of Medicine, Seoul, Republic of Korea., Oh JH; Department of Internal Medicine, Samsung Changwon Hospital, Sungkyunkwan University School of Medicine, Changwon, Republic of Korea., Na JO; Department of Internal Medicine, Korea University Guro Hospital, Korea University College of Medicine, Seoul, Republic of Korea., Kim DH; Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea., Cho EJ; Department of Internal Medicine, Yeouido St. Mary's Hospital, The Catholic University of Korea, Seoul, Republic of Korea., Yoon HJ; Department of Internal Medicine, Keimyung University Dongsan Hospital, Keimyung University College of Medicine, Daegu, Republic of Korea., Lee CJ; Department of Internal Medicine, Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea., Lee HC; Department of Internal Medicine, Pusan National University Hospital, Pusan National University School of Medicine, Busan, Republic of Korea., Lee HY; Department of Internal Medicine, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Republic of Korea., Sohn IS; Department of Cardiology, Kyung Hee University Hospital at Gangdong, Kyung Hee University College of Medicine, Seoul, Republic of Korea., Lee KS; Department of Internal Medicine, Eulji University Hospital, Eulji University School of Medicine, Daejeon, Republic of Korea., Kim DI; Department of Internal Medicine, Inje University Haeundae Paik Hospital, Inje University College of Medicine, Busan, Republic of Korea., Choi WG; Department of Internal Medicine, Chungbuk National University Hospital, Chungbuk National University College of Medicine, Cheongju, Republic of Korea., Chung WJ; Department of Cardiovascular Medicine, Gachon University Gil Medical Center, Gachon University College of Medicine, Incheon, Republic of Korea., Lee EM; Department of Internal Medicine, Dongguk University Ilsan Hospital, Dongguk University College of Medicine, Goyang, Republic of Korea., Choi SH; Department of Internal Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea., Choi S; Department of Internal Medicine, Hallym University Kangnam Sacred Heart Hospital, Hallym University College of Medicine, Seoul, Republic of Korea., Kang TS; Department of Internal Medicine, Dankook University Hospital, Dankook University College of Medicine, Cheonan, Republic of Korea., Ihm SH; Catholic Research Institute for Intractable Cardiovascular Disease, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.; Department of Internal Medicine, Bucheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea. |
| Source: | Drug design, development and therapy [Drug Des Devel Ther] 2026 May 15; Vol. 20, pp. 578736. Date of Electronic Publication: 2026 May 15 (Print Publication: 2026). |
| Publication Type: | Journal Article; Randomized Controlled Trial; Multicenter Study; Clinical Trial, Phase III; Comparative Study; Case Reports; Clinical Trial |
| Journal Info: | Publisher: Dove Press Limited Country of Publication: New Zealand NLM ID: 101475745 Publication Model: eCollection Cited Medium: Internet ISSN: 1177-8881 (Electronic) Linking ISSN: 11778881 NLM ISO Abbreviation: Drug Des Devel Ther Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 42163997 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Efficacy and Safety of Fimasartan/Indapamide Combination Therapy versus Fimasartan Monotherapy in Patients with Essential Hypertension Inadequately Responding to Fimasartan 30 mg (FINEDUO): A Randomized, Double-Blind, Multicenter, Phase III Study. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Youn+JC%22">Youn JC</searchLink>; Department of Internal Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.; Catholic Research Institute for Intractable Cardiovascular Disease, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Lee+SY%22">Lee SY</searchLink>; Department of Internal Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.; Catholic Research Institute for Intractable Cardiovascular Disease, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Yu+CW%22">Yu CW</searchLink>; Department of Internal Medicine, Korea University Anam Hospital, Korea University College of Medicine, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Sung+KC%22">Sung KC</searchLink>; Department of Internal Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Shin+J%22">Shin J</searchLink>; Department of Internal Medicine, Hanyang University Seoul Hospital, Hanyang University College of Medicine, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Oh+JH%22">Oh JH</searchLink>; Department of Internal Medicine, Samsung Changwon Hospital, Sungkyunkwan University School of Medicine, Changwon, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Na+JO%22">Na JO</searchLink>; Department of Internal Medicine, Korea University Guro Hospital, Korea University College of Medicine, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+DH%22">Kim DH</searchLink>; Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Cho+EJ%22">Cho EJ</searchLink>; Department of Internal Medicine, Yeouido St. Mary's Hospital, The Catholic University of Korea, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Yoon+HJ%22">Yoon HJ</searchLink>; Department of Internal Medicine, Keimyung University Dongsan Hospital, Keimyung University College of Medicine, Daegu, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Lee+CJ%22">Lee CJ</searchLink>; Department of Internal Medicine, Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Lee+HC%22">Lee HC</searchLink>; Department of Internal Medicine, Pusan National University Hospital, Pusan National University School of Medicine, Busan, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Lee+HY%22">Lee HY</searchLink>; Department of Internal Medicine, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Sohn+IS%22">Sohn IS</searchLink>; Department of Cardiology, Kyung Hee University Hospital at Gangdong, Kyung Hee University College of Medicine, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Lee+KS%22">Lee KS</searchLink>; Department of Internal Medicine, Eulji University Hospital, Eulji University School of Medicine, Daejeon, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+DI%22">Kim DI</searchLink>; Department of Internal Medicine, Inje University Haeundae Paik Hospital, Inje University College of Medicine, Busan, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Choi+WG%22">Choi WG</searchLink>; Department of Internal Medicine, Chungbuk National University Hospital, Chungbuk National University College of Medicine, Cheongju, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Chung+WJ%22">Chung WJ</searchLink>; Department of Cardiovascular Medicine, Gachon University Gil Medical Center, Gachon University College of Medicine, Incheon, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Lee+EM%22">Lee EM</searchLink>; Department of Internal Medicine, Dongguk University Ilsan Hospital, Dongguk University College of Medicine, Goyang, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Choi+SH%22">Choi SH</searchLink>; Department of Internal Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Choi+S%22">Choi S</searchLink>; Department of Internal Medicine, Hallym University Kangnam Sacred Heart Hospital, Hallym University College of Medicine, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kang+TS%22">Kang TS</searchLink>; Department of Internal Medicine, Dankook University Hospital, Dankook University College of Medicine, Cheonan, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Ihm+SH%22">Ihm SH</searchLink>; Catholic Research Institute for Intractable Cardiovascular Disease, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.; Department of Internal Medicine, Bucheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101475745%22">Drug design, development and therapy</searchLink> [Drug Des Devel Ther] 2026 May 15; Vol. 20, pp. 578736. <i>Date of Electronic Publication: </i>2026 May 15 (<i>Print Publication: </i>2026). – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Randomized Controlled Trial; Multicenter Study; Clinical Trial, Phase III; Comparative Study; Case Reports; Clinical Trial – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Dove+Press+Limited%22">Dove Press Limited </searchLink><i>Country of Publication: </i>New Zealand <i>NLM ID: </i>101475745 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Internet <i>ISSN: </i>1177-8881 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2211778881%22">11778881 </searchLink><i>NLM ISO Abbreviation: </i>Drug Des Devel Ther <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=42163997 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.2147/DDDT.S578736 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 578736 Titles: – TitleFull: Efficacy and Safety of Fimasartan/Indapamide Combination Therapy versus Fimasartan Monotherapy in Patients with Essential Hypertension Inadequately Responding to Fimasartan 30 mg (FINEDUO): A Randomized, Double-Blind, Multicenter, Phase III Study. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Youn JC – PersonEntity: Name: NameFull: Lee SY – PersonEntity: Name: NameFull: Yu CW – PersonEntity: Name: NameFull: Sung KC – PersonEntity: Name: NameFull: Shin J – PersonEntity: Name: NameFull: Oh JH – PersonEntity: Name: NameFull: Na JO – PersonEntity: Name: NameFull: Kim DH – PersonEntity: Name: NameFull: Cho EJ – PersonEntity: Name: NameFull: Yoon HJ – PersonEntity: Name: NameFull: Lee CJ – PersonEntity: Name: NameFull: Lee HC – PersonEntity: Name: NameFull: Lee HY – PersonEntity: Name: NameFull: Sohn IS – PersonEntity: Name: NameFull: Lee KS – PersonEntity: Name: NameFull: Kim DI – PersonEntity: Name: NameFull: Choi WG – PersonEntity: Name: NameFull: Chung WJ – PersonEntity: Name: NameFull: Lee EM – PersonEntity: Name: NameFull: Choi SH – PersonEntity: Name: NameFull: Choi S – PersonEntity: Name: NameFull: Kang TS – PersonEntity: Name: NameFull: Ihm SH IsPartOfRelationships: – BibEntity: Dates: – D: 15 M: 05 Text: 2026 May 15 Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 1177-8881 Numbering: – Type: volume Value: 20 Titles: – TitleFull: Drug design, development and therapy Type: main |
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