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The impact of breast cancer polygenic risk score disclosure on decisional conflict around risk-reducing mastectomy in women with pathogenic BRCA1/2 variants.

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Title: The impact of breast cancer polygenic risk score disclosure on decisional conflict around risk-reducing mastectomy in women with pathogenic BRCA1/2 variants.
Authors: Ongaro G; Memorial Sloan Kettering Cancer Center, New York, NY., Salafia C; Memorial Sloan Kettering Cancer Center, New York, NY., Sheikh R; Memorial Sloan Kettering Cancer Center, New York, NY., Schofield E; Memorial Sloan Kettering Cancer Center, New York, NY., Clark DF; University of Pennsylvania, Philadelphia, PA., Ebrahimzadeh J; University of Pennsylvania, Philadelphia, PA., Chittenden A; Dana-Farber Cancer Institute, Boston, MA., Stopfer JE; Dana-Farber Cancer Institute, Boston, MA., Brower J; University of Pennsylvania, Philadelphia, PA., Symecko H; University of Pennsylvania, Philadelphia, PA., Ovadia H; Memorial Sloan Kettering Cancer Center, New York, NY., Husband A; Dana-Farber Cancer Institute, Boston, MA., Barr H; Dana-Farber Cancer Institute, Boston, MA., Mukherjee S; Memorial Sloan Kettering Cancer Center, New York, NY., Hay JL; Memorial Sloan Kettering Cancer Center, New York, NY., Stadler ZK; Memorial Sloan Kettering Cancer Center, New York, NY., Offit K; Memorial Sloan Kettering Cancer Center, New York, NY., Garber JE; Dana-Farber Cancer Institute, Boston, MA., Domchek SM; University of Pennsylvania, Philadelphia, PA., Robson ME; Memorial Sloan Kettering Cancer Center, New York, NY., Hamilton JG; Memorial Sloan Kettering Cancer Center, New York, NY. Electronic address: hamiltoj@mskcc.org.
Source: Genetics in medicine : official journal of the American College of Medical Genetics [Genet Med] 2026 May 21; Vol. 28 (8), pp. 102609. Date of Electronic Publication: 2026 May 21.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 9815831 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1530-0366 (Electronic) Linking ISSN: 10983600 NLM ISO Abbreviation: Genet Med Subsets: MEDLINE
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