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Multiomic analyses delineate human neuroendocrine tumor cell states in relation to normal enteroendocrine cell ontogeny.

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Title: Multiomic analyses delineate human neuroendocrine tumor cell states in relation to normal enteroendocrine cell ontogeny.
Authors: Singh PN; Department of Medical Oncology and.; Center for Functional Cancer Epigenetics, Dana-Farber Cancer Institute, Boston, Massachusetts, USA.; Department of Medicine, Harvard Medical School, Boston, Massachusetts, USA., Hadj Bachir E; Department of Medical Oncology and.; Center for Functional Cancer Epigenetics, Dana-Farber Cancer Institute, Boston, Massachusetts, USA.; Department of Medicine, Harvard Medical School, Boston, Massachusetts, USA., Howe JR; Department of Surgery and., Bellizzi AM; Department of Pathology, Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA., Cejas P; Center for Functional Cancer Epigenetics, Dana-Farber Cancer Institute, Boston, Massachusetts, USA., Madha-Krause S; Department of Medical Oncology and., Epstein CB; Epigenomics Program, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA., Chan JA; Department of Medical Oncology and.; Department of Medicine, Harvard Medical School, Boston, Massachusetts, USA., Bernstein B; Epigenomics Program, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA.; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts, USA.; Department of Pathology, Harvard Medical School, Boston, Massachusetts, USA., Kulke MH; Department of Medical Oncology and.; Department of Medicine, Harvard Medical School, Boston, Massachusetts, USA., Zhou Q; Division of Regenerative Medicine and Hartman Institute for Therapeutic Organ Regeneration, Department of Medicine, Weill Cornell Medicine, New York, New York, USA., Shivdasani RA; Department of Medical Oncology and.; Center for Functional Cancer Epigenetics, Dana-Farber Cancer Institute, Boston, Massachusetts, USA.; Department of Medicine, Harvard Medical School, Boston, Massachusetts, USA.
Source: The Journal of clinical investigation [J Clin Invest] 2026 May 21; Vol. 136 (13). Date of Electronic Publication: 2026 May 21 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model: eCollection Cited Medium: Internet ISSN: 1558-8238 (Electronic) Linking ISSN: 00219738 NLM ISO Abbreviation: J Clin Invest Subsets: MEDLINE
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  Data: Multiomic analyses delineate human neuroendocrine tumor cell states in relation to normal enteroendocrine cell ontogeny.
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  Data: <searchLink fieldCode="AU" term="%22Singh+PN%22">Singh PN</searchLink>; Department of Medical Oncology and.; Center for Functional Cancer Epigenetics, Dana-Farber Cancer Institute, Boston, Massachusetts, USA.; Department of Medicine, Harvard Medical School, Boston, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Hadj+Bachir+E%22">Hadj Bachir E</searchLink>; Department of Medical Oncology and.; Center for Functional Cancer Epigenetics, Dana-Farber Cancer Institute, Boston, Massachusetts, USA.; Department of Medicine, Harvard Medical School, Boston, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Howe+JR%22">Howe JR</searchLink>; Department of Surgery and.<br /><searchLink fieldCode="AU" term="%22Bellizzi+AM%22">Bellizzi AM</searchLink>; Department of Pathology, Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA.<br /><searchLink fieldCode="AU" term="%22Cejas+P%22">Cejas P</searchLink>; Center for Functional Cancer Epigenetics, Dana-Farber Cancer Institute, Boston, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Madha-Krause+S%22">Madha-Krause S</searchLink>; Department of Medical Oncology and.<br /><searchLink fieldCode="AU" term="%22Epstein+CB%22">Epstein CB</searchLink>; Epigenomics Program, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Chan+JA%22">Chan JA</searchLink>; Department of Medical Oncology and.; Department of Medicine, Harvard Medical School, Boston, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Bernstein+B%22">Bernstein B</searchLink>; Epigenomics Program, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA.; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts, USA.; Department of Pathology, Harvard Medical School, Boston, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Kulke+MH%22">Kulke MH</searchLink>; Department of Medical Oncology and.; Department of Medicine, Harvard Medical School, Boston, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Zhou+Q%22">Zhou Q</searchLink>; Division of Regenerative Medicine and Hartman Institute for Therapeutic Organ Regeneration, Department of Medicine, Weill Cornell Medicine, New York, New York, USA.<br /><searchLink fieldCode="AU" term="%22Shivdasani+RA%22">Shivdasani RA</searchLink>; Department of Medical Oncology and.; Center for Functional Cancer Epigenetics, Dana-Farber Cancer Institute, Boston, Massachusetts, USA.; Department of Medicine, Harvard Medical School, Boston, Massachusetts, USA.
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  Data: <searchLink fieldCode="JN" term="%227802877%22">The Journal of clinical investigation</searchLink> [J Clin Invest] 2026 May 21; Vol. 136 (13). <i>Date of Electronic Publication: </i>2026 May 21 (<i>Print Publication: </i>2026).
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        Value: 10.1172/JCI197772
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              Text: 2026 May 21
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