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Optimizing adjuvant therapy selection with machine learning after transoral surgery in HPV-related oropharyngeal cancer.

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Title: Optimizing adjuvant therapy selection with machine learning after transoral surgery in HPV-related oropharyngeal cancer.
Authors: Costantino A; Otorhinolaryngology Unit, IRCCS Humanitas Research Hospital, Via Manni zo56, Milan, Rozzano 20089, Italy; Department of Otolaryngology - Head and Neck Surgery, AdventHealth Orlando, 410 Celebration Place, Celebration, FL 34747, United States., Paleri V; Head and Neck Unit, The Royal Marsden National Health Service Foundation Trust, London, UK; The Institute of Cancer Research, London, UK; International Centre for Recurrent Head and Neck Cancer, London, UK., Williamson A; Head and Neck Unit, The Royal Marsden National Health Service Foundation Trust, London, UK; The Institute of Cancer Research, London, UK; International Centre for Recurrent Head and Neck Cancer, London, UK., Zhu J; Center for Academic Research Excellence, AdventHealth Research Institute, Orlando, FL 32804, United States., Bossi P; Medical Oncology and Hematology Unit, IRCCS Humanitas Research Hospital, Via Manzoni 56, Milan, Rozzano 20089, Italy; Department of Biomedical Sciences, Humanitas University, Via Rita Levi Montalcini 4, Milan, Pieve Emanuele 20072, Italy., Ferreli F; Otorhinolaryngology Unit, IRCCS Humanitas Research Hospital, Via Manni zo56, Milan, Rozzano 20089, Italy; Department of Biomedical Sciences, Humanitas University, Via Rita Levi Montalcini 4, Milan, Pieve Emanuele 20072, Italy., Spriano G; Otorhinolaryngology Unit, IRCCS Humanitas Research Hospital, Via Manni zo56, Milan, Rozzano 20089, Italy; Department of Biomedical Sciences, Humanitas University, Via Rita Levi Montalcini 4, Milan, Pieve Emanuele 20072, Italy., Haughey BH; Department of Otolaryngology - Head and Neck Surgery, AdventHealth Orlando, 410 Celebration Place, Celebration, FL 34747, United States; Department of Otolaryngology - Head and Neck Surgery, University of South Florida Morsani College of Medicine, Tampa, FL, United States; Department of Surgery, University of Auckland School of Medicine and Allied Health Sciences, Auckland, New Zealand., Magnuson JS; Department of Otolaryngology - Head and Neck Surgery, AdventHealth Orlando, 410 Celebration Place, Celebration, FL 34747, United States. Electronic address: Scott.Magnuson.MD@AdventHealth.com.
Source: Oral oncology [Oral Oncol] 2026 Aug; Vol. 179, pp. 108024. Date of Electronic Publication: 2026 May 21.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: England NLM ID: 9709118 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0593 (Electronic) Linking ISSN: 13688375 NLM ISO Abbreviation: Oral Oncol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Costantino+A%22">Costantino A</searchLink>; Otorhinolaryngology Unit, IRCCS Humanitas Research Hospital, Via Manni zo56, Milan, Rozzano 20089, Italy; Department of Otolaryngology - Head and Neck Surgery, AdventHealth Orlando, 410 Celebration Place, Celebration, FL 34747, United States.<br /><searchLink fieldCode="AU" term="%22Paleri+V%22">Paleri V</searchLink>; Head and Neck Unit, The Royal Marsden National Health Service Foundation Trust, London, UK; The Institute of Cancer Research, London, UK; International Centre for Recurrent Head and Neck Cancer, London, UK.<br /><searchLink fieldCode="AU" term="%22Williamson+A%22">Williamson A</searchLink>; Head and Neck Unit, The Royal Marsden National Health Service Foundation Trust, London, UK; The Institute of Cancer Research, London, UK; International Centre for Recurrent Head and Neck Cancer, London, UK.<br /><searchLink fieldCode="AU" term="%22Zhu+J%22">Zhu J</searchLink>; Center for Academic Research Excellence, AdventHealth Research Institute, Orlando, FL 32804, United States.<br /><searchLink fieldCode="AU" term="%22Bossi+P%22">Bossi P</searchLink>; Medical Oncology and Hematology Unit, IRCCS Humanitas Research Hospital, Via Manzoni 56, Milan, Rozzano 20089, Italy; Department of Biomedical Sciences, Humanitas University, Via Rita Levi Montalcini 4, Milan, Pieve Emanuele 20072, Italy.<br /><searchLink fieldCode="AU" term="%22Ferreli+F%22">Ferreli F</searchLink>; Otorhinolaryngology Unit, IRCCS Humanitas Research Hospital, Via Manni zo56, Milan, Rozzano 20089, Italy; Department of Biomedical Sciences, Humanitas University, Via Rita Levi Montalcini 4, Milan, Pieve Emanuele 20072, Italy.<br /><searchLink fieldCode="AU" term="%22Spriano+G%22">Spriano G</searchLink>; Otorhinolaryngology Unit, IRCCS Humanitas Research Hospital, Via Manni zo56, Milan, Rozzano 20089, Italy; Department of Biomedical Sciences, Humanitas University, Via Rita Levi Montalcini 4, Milan, Pieve Emanuele 20072, Italy.<br /><searchLink fieldCode="AU" term="%22Haughey+BH%22">Haughey BH</searchLink>; Department of Otolaryngology - Head and Neck Surgery, AdventHealth Orlando, 410 Celebration Place, Celebration, FL 34747, United States; Department of Otolaryngology - Head and Neck Surgery, University of South Florida Morsani College of Medicine, Tampa, FL, United States; Department of Surgery, University of Auckland School of Medicine and Allied Health Sciences, Auckland, New Zealand.<br /><searchLink fieldCode="AU" term="%22Magnuson+JS%22">Magnuson JS</searchLink>; Department of Otolaryngology - Head and Neck Surgery, AdventHealth Orlando, 410 Celebration Place, Celebration, FL 34747, United States. Electronic address: Scott.Magnuson.MD@AdventHealth.com.
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  Data: <searchLink fieldCode="JN" term="%229709118%22">Oral oncology</searchLink> [Oral Oncol] 2026 Aug; Vol. 179, pp. 108024. <i>Date of Electronic Publication: </i>2026 May 21.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%22">Elsevier </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>9709118 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1879-0593 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2213688375%22">13688375 </searchLink><i>NLM ISO Abbreviation: </i>Oral Oncol <i>Subsets: </i>MEDLINE
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              Text: 2026 Aug
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