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Genome-wide association study of idiopathic pulmonary fibrosis susceptibility using clinically curated European ancestry datasets.

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Title: Genome-wide association study of idiopathic pulmonary fibrosis susceptibility using clinically curated European ancestry datasets.
Authors: Chin D; Division of Public Health and Epidemiology, School of Medical Sciences, University of Leicester, Leicester, UK.; University Hospitals of Leicester NHS Trust, Leicester, UK.; Centre for Fibrosis Research, University of Leicester, Leicester, UK.; Contributed equally., Hernandez-Beeftink T; Division of Public Health and Epidemiology, School of Medical Sciences, University of Leicester, Leicester, UK.; University Hospitals of Leicester NHS Trust, Leicester, UK.; Centre for Fibrosis Research, University of Leicester, Leicester, UK.; Contributed equally., Donoghue L; Genentech, South San Francisco, CA, USA., Guillen-Guio B; Division of Public Health and Epidemiology, School of Medical Sciences, University of Leicester, Leicester, UK.; University Hospitals of Leicester NHS Trust, Leicester, UK.; Centre for Fibrosis Research, University of Leicester, Leicester, UK.; Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBERES), Instituto de Salud Carlos III, Madrid, Spain., Leavy OC; Division of Public Health and Epidemiology, School of Medical Sciences, University of Leicester, Leicester, UK.; University Hospitals of Leicester NHS Trust, Leicester, UK.; Centre for Fibrosis Research, University of Leicester, Leicester, UK., Adegunsoye A; University of Chicago, Chicago, IL, USA., Booth HL; University College London Hospitals, London, UK., Fahy WA; GlaxoSmithKline, London, UK., Fingerlin TE; National Jewish Health, Denver, CO, USA., Gooptu B; University Hospitals of Leicester NHS Trust, Leicester, UK.; Centre for Fibrosis Research, University of Leicester, Leicester, UK., Hall IP; Centre for Respiratory Research, NIHR Nottingham Biomedical Research Centre, School of Medicine, Biodiscovery Institute, University of Nottingham, Nottingham, UK., Hart SP; University of Hull, Hull, UK., Hill MR; University of Oxford, Oxford, UK., Hirani N; University of Edinburgh, Edinburgh, UK., Johnson SR; Centre for Respiratory Research, NIHR Biomedical Research Centre and Biodiscovery Institute, Translational Medical Sciences, School of Medicine, University of Nottingham, Nottingham, UK., Kaminski N; Yale School of Medicine, New Haven, CT, USA., Lorenzo-Salazar JM; Genomics Division, Instituto Tecnologico y de Energias Renovables, Santa Cruz de Tenerife, Spain., Ma SF; University of Virginia, Charlottesville, VA, USA., McAnulty RJ; University College London, London, UK., McCarthy MI; Genentech, South San Francisco, CA, USA., Stockwell AD; Genentech, South San Francisco, CA, USA., Maher TM; NIHR Imperial Biomedical Research Unit, National Heart and Lung Institute, Imperial College London, London, UK.; Keck Medicine of USC, University of Southern California, Los Angeles, CA, USA., Millar AB; University of Bristol, Bristol, UK., Molyneaux PL; National Heart and Lung Institute, Imperial College London, London, UK., Molina-Molina M; Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBERES), Instituto de Salud Carlos III, Madrid, Spain.; Servei de Pneumologia, Hospital Universitari de Bellvitge (HUB), Laboratori de Pneumologia Experimental, Institut de Investigació Biomèdica de Bellvitge (IDIBELL), Barcelona, Spain.; Facultat de Medicine, Universitat de Barcelona, Barcelona, Spain., Navaratnam V; Department of Respiratory Medicine, Sir Charles Gardiner Hospital, Perth, Australia.; Centre for Respiratory Research, University of Western Australia, Perth, Australia., Neighbors M; Genentech, South San Francisco, CA, USA., Oldham JM; University of Michigan, Ann Arbor, MI, USA., Parfrey H; Royal Papworth Hospital NHS Foundation Trust, Cambridge, UK., Saini G; University of Nottingham, Nottingham, UK., Sayers I; Centre for Respiratory Research, NIHR Nottingham Biomedical Research Centre, School of Medicine, Biodiscovery Institute, University of Nottingham, Nottingham, UK., Sheng XR; Genentech, South San Francisco, CA, USA., Stewart ID; Imperial College London, London, UK., Strek ME; University of Chicago, Chicago, IL, USA., Tobin MD; Division of Public Health and Epidemiology, School of Medical Sciences, University of Leicester, Leicester, UK.; University Hospitals of Leicester NHS Trust, Leicester, UK., Whyte MKB; University of Edinburgh, Edinburgh, UK., Zarcone MC; NIHR Imperial Biomedical Research Unit, National Heart and Lung Institute, Imperial College London, London, UK., Zhang Y; University of Pittsburgh, Pittsburgh, PA, USA., Martinez F; UMass Chan Medical School, Worcester, MA, USA., Yaspan BL; Genentech, South San Francisco, CA, USA., Reynolds CJ; Imperial College, London, UK., Schwartz DA; University of Colorado Medicine, Aurora, CO, USA., Flores C; Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBERES), Instituto de Salud Carlos III, Madrid, Spain.; Genomics Division, Instituto Tecnologico y de Energias Renovables, Santa Cruz de Tenerife, Spain.; Research Unit, Hospital Universitario Nuestra Señora de Candelaria, Instituto de Investigación Sanitaria de Canarias, Santa Cruz de Tenerife, Spain.; Facultad de Ciencias de la Salud, Universidad Fernando Pessoa Canarias, Las Palmas de Gran Canaria, Spain., Noth I; University of Virginia, Charlottesville, VA, USA., Jenkins RG; NIHR Imperial Biomedical Research Unit, National Heart and Lung Institute, Imperial College London, London, UK., Allen RJ; Division of Public Health and Epidemiology, School of Medical Sciences, University of Leicester, Leicester, UK.; University Hospitals of Leicester NHS Trust, Leicester, UK.; Centre for Fibrosis Research, University of Leicester, Leicester, UK., Wain LV; Division of Public Health and Epidemiology, School of Medical Sciences, University of Leicester, Leicester, UK lvw1@leicester.ac.uk.; University Hospitals of Leicester NHS Trust, Leicester, UK.; Centre for Fibrosis Research, University of Leicester, Leicester, UK.
Corporate Authors: CleanUP-IPF Investigators of the Pulmonary Trials Cooperative
Source: The European respiratory journal [Eur Respir J] 2026 Jul 09; Vol. 68 (1). Date of Electronic Publication: 2026 Jul 09 (Print Publication: 2026).
Publication Type: Letter
Journal Info: Publisher: European Respiratory Society Country of Publication: England NLM ID: 8803460 Publication Model: Electronic-Print Cited Medium: Internet ISSN: 1399-3003 (Electronic) Linking ISSN: 09031936 NLM ISO Abbreviation: Eur Respir J Subsets: MEDLINE; In Process
Database: MEDLINE Ultimate
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  Data: Genome-wide association study of idiopathic pulmonary fibrosis susceptibility using clinically curated European ancestry datasets.
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  Data: <searchLink fieldCode="AU" term="%22Chin+D%22">Chin D</searchLink>; Division of Public Health and Epidemiology, School of Medical Sciences, University of Leicester, Leicester, UK.; University Hospitals of Leicester NHS Trust, Leicester, UK.; Centre for Fibrosis Research, University of Leicester, Leicester, UK.; Contributed equally.<br /><searchLink fieldCode="AU" term="%22Hernandez-Beeftink+T%22">Hernandez-Beeftink T</searchLink>; Division of Public Health and Epidemiology, School of Medical Sciences, University of Leicester, Leicester, UK.; University Hospitals of Leicester NHS Trust, Leicester, UK.; Centre for Fibrosis Research, University of Leicester, Leicester, UK.; Contributed equally.<br /><searchLink fieldCode="AU" term="%22Donoghue+L%22">Donoghue L</searchLink>; Genentech, South San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Guillen-Guio+B%22">Guillen-Guio B</searchLink>; Division of Public Health and Epidemiology, School of Medical Sciences, University of Leicester, Leicester, UK.; University Hospitals of Leicester NHS Trust, Leicester, UK.; Centre for Fibrosis Research, University of Leicester, Leicester, UK.; Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBERES), Instituto de Salud Carlos III, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Leavy+OC%22">Leavy OC</searchLink>; Division of Public Health and Epidemiology, School of Medical Sciences, University of Leicester, Leicester, UK.; University Hospitals of Leicester NHS Trust, Leicester, UK.; Centre for Fibrosis Research, University of Leicester, Leicester, UK.<br /><searchLink fieldCode="AU" term="%22Adegunsoye+A%22">Adegunsoye A</searchLink>; University of Chicago, Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Booth+HL%22">Booth HL</searchLink>; University College London Hospitals, London, UK.<br /><searchLink fieldCode="AU" term="%22Fahy+WA%22">Fahy WA</searchLink>; GlaxoSmithKline, London, UK.<br /><searchLink fieldCode="AU" term="%22Fingerlin+TE%22">Fingerlin TE</searchLink>; 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Yale School of Medicine, New Haven, CT, USA.<br /><searchLink fieldCode="AU" term="%22Lorenzo-Salazar+JM%22">Lorenzo-Salazar JM</searchLink>; Genomics Division, Instituto Tecnologico y de Energias Renovables, Santa Cruz de Tenerife, Spain.<br /><searchLink fieldCode="AU" term="%22Ma+SF%22">Ma SF</searchLink>; University of Virginia, Charlottesville, VA, USA.<br /><searchLink fieldCode="AU" term="%22McAnulty+RJ%22">McAnulty RJ</searchLink>; University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22McCarthy+MI%22">McCarthy MI</searchLink>; Genentech, South San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Stockwell+AD%22">Stockwell AD</searchLink>; Genentech, South San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Maher+TM%22">Maher TM</searchLink>; NIHR Imperial Biomedical Research Unit, National Heart and Lung Institute, Imperial College London, London, UK.; Keck Medicine of USC, University of Southern California, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Millar+AB%22">Millar AB</searchLink>; 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