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Hierarchical multi-timescale structural dynamics of the disordered N-terminal of p53.

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Title: Hierarchical multi-timescale structural dynamics of the disordered N-terminal of p53.
Authors: Szöllősi D; Max Planck Institute for Multidisciplinary Sciences, Department of Theoretical and Computational Biophysics, Göttingen, Germany., Pratihar S; Max Planck Institute for Multidisciplinary Sciences, Department of NMR-Based Structural Biology, Göttingen, Germany.; Columbia University, Department of Biochemistry and Molecular Biophysics, New York, NY, USA., Mukhopadhyay D; Max Planck Institute for Multidisciplinary Sciences, Department of NMR-Based Structural Biology, Göttingen, Germany., Rout AK; Max Planck Institute for Multidisciplinary Sciences, Department of NMR-Based Structural Biology, Göttingen, Germany.; Institute of Chemistry and Metabolomics, University of Lübeck, Lübeck, Germany., Han M; Max Planck Institute for Multidisciplinary Sciences, Department of NMR-Based Structural Biology, Göttingen, Germany., Reddy GJ; Max Planck Institute for Multidisciplinary Sciences, Department of NMR-Based Structural Biology, Göttingen, Germany.; NMR Division, Department of Analytical & Structural Chemistry, CSIR-Indian Institute of Chemical Technology, Hyderabad, India., Ebersberger N; Max Planck Institute for Multidisciplinary Sciences, Department of NMR-Based Structural Biology, Göttingen, Germany.; Institute of Biochemistry, University of Lübeck, Lübeck, Germany., Becker S; Max Planck Institute for Multidisciplinary Sciences, Department of NMR-Based Structural Biology, Göttingen, Germany., Nagy G; Max Planck Institute for Multidisciplinary Sciences, Department of Theoretical and Computational Biophysics, Göttingen, Germany., Rauscher S; Department of Chemical and Physical Sciences, University of Toronto Mississauga, Mississauga, ON, Canada.; Department of Physics, University of Toronto, Toronto, ON, Canada.; Department of Chemistry, University of Toronto, Toronto, ON, Canada., Lee D; Max Planck Institute for Multidisciplinary Sciences, Department of NMR-Based Structural Biology, Göttingen, Germany.; Biopharmaceutical Research Center, Korea Basic Science Institute, Cheongju-Si, South Korea., Klement R; Max Planck Institute for Multidisciplinary Sciences, Department of Theoretical and Computational Biophysics, Göttingen, Germany., Griesinger C; Max Planck Institute for Multidisciplinary Sciences, Department of NMR-Based Structural Biology, Göttingen, Germany. cigr@mpinat.mpg.de., Grubmüller H; Max Planck Institute for Multidisciplinary Sciences, Department of Theoretical and Computational Biophysics, Göttingen, Germany. hgrubmu@mpinat.mpg.de.
Source: Nature communications [Nat Commun] 2026 May 21; Vol. 17 (1). Date of Electronic Publication: 2026 May 21.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Szöllősi+D%22">Szöllősi D</searchLink>; Max Planck Institute for Multidisciplinary Sciences, Department of Theoretical and Computational Biophysics, Göttingen, Germany.<br /><searchLink fieldCode="AU" term="%22Pratihar+S%22">Pratihar S</searchLink>; Max Planck Institute for Multidisciplinary Sciences, Department of NMR-Based Structural Biology, Göttingen, Germany.; Columbia University, Department of Biochemistry and Molecular Biophysics, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Mukhopadhyay+D%22">Mukhopadhyay D</searchLink>; Max Planck Institute for Multidisciplinary Sciences, Department of NMR-Based Structural Biology, Göttingen, Germany.<br /><searchLink fieldCode="AU" term="%22Rout+AK%22">Rout AK</searchLink>; Max Planck Institute for Multidisciplinary Sciences, Department of NMR-Based Structural Biology, Göttingen, Germany.; Institute of Chemistry and Metabolomics, University of Lübeck, Lübeck, Germany.<br /><searchLink fieldCode="AU" term="%22Han+M%22">Han M</searchLink>; Max Planck Institute for Multidisciplinary Sciences, Department of NMR-Based Structural Biology, Göttingen, Germany.<br /><searchLink fieldCode="AU" term="%22Reddy+GJ%22">Reddy GJ</searchLink>; Max Planck Institute for Multidisciplinary Sciences, Department of NMR-Based Structural Biology, Göttingen, Germany.; NMR Division, Department of Analytical & Structural Chemistry, CSIR-Indian Institute of Chemical Technology, Hyderabad, India.<br /><searchLink fieldCode="AU" term="%22Ebersberger+N%22">Ebersberger N</searchLink>; Max Planck Institute for Multidisciplinary Sciences, Department of NMR-Based Structural Biology, Göttingen, Germany.; Institute of Biochemistry, University of Lübeck, Lübeck, Germany.<br /><searchLink fieldCode="AU" term="%22Becker+S%22">Becker S</searchLink>; Max Planck Institute for Multidisciplinary Sciences, Department of NMR-Based Structural Biology, Göttingen, Germany.<br /><searchLink fieldCode="AU" term="%22Nagy+G%22">Nagy G</searchLink>; Max Planck Institute for Multidisciplinary Sciences, Department of Theoretical and Computational Biophysics, Göttingen, Germany.<br /><searchLink fieldCode="AU" term="%22Rauscher+S%22">Rauscher S</searchLink>; Department of Chemical and Physical Sciences, University of Toronto Mississauga, Mississauga, ON, Canada.; Department of Physics, University of Toronto, Toronto, ON, Canada.; Department of Chemistry, University of Toronto, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Lee+D%22">Lee D</searchLink>; Max Planck Institute for Multidisciplinary Sciences, Department of NMR-Based Structural Biology, Göttingen, Germany.; Biopharmaceutical Research Center, Korea Basic Science Institute, Cheongju-Si, South Korea.<br /><searchLink fieldCode="AU" term="%22Klement+R%22">Klement R</searchLink>; Max Planck Institute for Multidisciplinary Sciences, Department of Theoretical and Computational Biophysics, Göttingen, Germany.<br /><searchLink fieldCode="AU" term="%22Griesinger+C%22">Griesinger C</searchLink>; Max Planck Institute for Multidisciplinary Sciences, Department of NMR-Based Structural Biology, Göttingen, Germany. cigr@mpinat.mpg.de.<br /><searchLink fieldCode="AU" term="%22Grubmüller+H%22">Grubmüller H</searchLink>; Max Planck Institute for Multidisciplinary Sciences, Department of Theoretical and Computational Biophysics, Göttingen, Germany. hgrubmu@mpinat.mpg.de.
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