MSL2 disruption leads to autism-like behaviors, impairs neurogenesis, and alters histone H4K16 acetylation.

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Title: MSL2 disruption leads to autism-like behaviors, impairs neurogenesis, and alters histone H4K16 acetylation.
Authors: Luo S; Hunan Key Laboratory of Medical Genetics, Hunan Key Laboratory of Animal Models for Human Diseases, School of Life Sciences, Central South University, Changsha, 410078, Hunan, China., Qu S; Hunan Key Laboratory of Medical Genetics, Hunan Key Laboratory of Animal Models for Human Diseases, School of Life Sciences, Central South University, Changsha, 410078, Hunan, China., Tan S; Hunan Key Laboratory of Medical Genetics, Hunan Key Laboratory of Animal Models for Human Diseases, School of Life Sciences, Central South University, Changsha, 410078, Hunan, China., Song Z; Hunan Key Laboratory of Medical Genetics, Hunan Key Laboratory of Animal Models for Human Diseases, School of Life Sciences, Central South University, Changsha, 410078, Hunan, China., Lv Y; Hunan Key Laboratory of Medical Genetics, Hunan Key Laboratory of Animal Models for Human Diseases, School of Life Sciences, Central South University, Changsha, 410078, Hunan, China., Jia X; Hunan Key Laboratory of Medical Genetics, Hunan Key Laboratory of Animal Models for Human Diseases, School of Life Sciences, Central South University, Changsha, 410078, Hunan, China.; MOE Key Lab of Rare Pediatric Diseases, Center for Medical Genetics, School of Life Sciences, Central South University, Changsha, 410078, Hunan, China., Tan J; Hunan Key Laboratory of Medical Genetics, Hunan Key Laboratory of Animal Models for Human Diseases, School of Life Sciences, Central South University, Changsha, 410078, Hunan, China.; MOE Key Lab of Rare Pediatric Diseases, Center for Medical Genetics, School of Life Sciences, Central South University, Changsha, 410078, Hunan, China., Chen G; Hunan Key Laboratory of Medical Genetics, Hunan Key Laboratory of Animal Models for Human Diseases, School of Life Sciences, Central South University, Changsha, 410078, Hunan, China. 223028@csu.edu.cn.; MOE Key Lab of Rare Pediatric Diseases, Center for Medical Genetics, School of Life Sciences, Central South University, Changsha, 410078, Hunan, China. 223028@csu.edu.cn., Guo H; Hunan Key Laboratory of Medical Genetics, Hunan Key Laboratory of Animal Models for Human Diseases, School of Life Sciences, Central South University, Changsha, 410078, Hunan, China. guohui2@csu.edu.cn.; MOE Key Lab of Rare Pediatric Diseases, Center for Medical Genetics, School of Life Sciences, Central South University, Changsha, 410078, Hunan, China. guohui2@csu.edu.cn.; Furong Laboratory, Changsha, 410078, Hunan, China. guohui2@csu.edu.cn., Xia K; Hunan Key Laboratory of Medical Genetics, Hunan Key Laboratory of Animal Models for Human Diseases, School of Life Sciences, Central South University, Changsha, 410078, Hunan, China. xiakun@sklmg.edu.cn.; MOE Key Lab of Rare Pediatric Diseases, Center for Medical Genetics, School of Life Sciences, Central South University, Changsha, 410078, Hunan, China. xiakun@sklmg.edu.cn.; Furong Laboratory, Changsha, 410078, Hunan, China. xiakun@sklmg.edu.cn.; MOE Key Lab of Rare Pediatric Diseases, School of Basic Medicine, Hengyang Medical College, University of South China, Hengyang, 421001, Hunan, China. xiakun@sklmg.edu.cn.
Source: Cellular and molecular life sciences : CMLS [Cell Mol Life Sci] 2026 May 22; Vol. 83 (1). Date of Electronic Publication: 2026 May 22.
Publication Type: Journal Article
Journal Info: Publisher: Springer Country of Publication: Switzerland NLM ID: 9705402 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-9071 (Electronic) Linking ISSN: 1420682X NLM ISO Abbreviation: Cell Mol Life Sci Subsets: MEDLINE
Database: MEDLINE Ultimate
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