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IL-1β Pathway Inhibition in Asthma and COPD: Strong Biological Rationale, Disappointing Clinical Trials, and Emerging New Opportunities.

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Title: IL-1β Pathway Inhibition in Asthma and COPD: Strong Biological Rationale, Disappointing Clinical Trials, and Emerging New Opportunities.
Authors: Cazzola M; Unit of Respiratory Medicine, Department of Experimental Medicine, University of Rome 'Tor Vergata', Rome, Italy. mario.cazzola@uniroma2.it., Page CP; Institute of Pharmaceutical Science, King's College London, London, UK., Matera MG; Unit of Pharmacology, Department of Experimental Medicine, University of Campania 'Luigi Vanvitelli', Naples, Italy.
Source: Lung [Lung] 2026 May 22; Vol. 204 (1). Date of Electronic Publication: 2026 May 22.
Publication Type: Journal Article; Review
Journal Info: Publisher: Springer Verlag Country of Publication: United States NLM ID: 7701875 Publication Model: Electronic Cited Medium: Internet ISSN: 1432-1750 (Electronic) Linking ISSN: 03412040 NLM ISO Abbreviation: Lung Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: IL-1β Pathway Inhibition in Asthma and COPD: Strong Biological Rationale, Disappointing Clinical Trials, and Emerging New Opportunities.
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  Data: <searchLink fieldCode="AU" term="%22Cazzola+M%22">Cazzola M</searchLink>; Unit of Respiratory Medicine, Department of Experimental Medicine, University of Rome 'Tor Vergata', Rome, Italy. mario.cazzola@uniroma2.it.<br /><searchLink fieldCode="AU" term="%22Page+CP%22">Page CP</searchLink>; Institute of Pharmaceutical Science, King's College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Matera+MG%22">Matera MG</searchLink>; Unit of Pharmacology, Department of Experimental Medicine, University of Campania 'Luigi Vanvitelli', Naples, Italy.
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  Data: <searchLink fieldCode="JN" term="%227701875%22">Lung</searchLink> [Lung] 2026 May 22; Vol. 204 (1). <i>Date of Electronic Publication: </i>2026 May 22.
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        Value: 10.1007/s00408-026-00897-9
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      – TitleFull: IL-1β Pathway Inhibition in Asthma and COPD: Strong Biological Rationale, Disappointing Clinical Trials, and Emerging New Opportunities.
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              Text: 2026 May 22
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              Y: 2026
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