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Interpretable Feature Extraction from Clinical Notes for Sepsis Prediction: Comparing Rule-Based, LLM, and Hybrid Approaches.

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Title: Interpretable Feature Extraction from Clinical Notes for Sepsis Prediction: Comparing Rule-Based, LLM, and Hybrid Approaches.
Authors: Frey N; Institute of Medical Informatics, Charité - Universitätsmedizin Berlin, Germany., Meyer-Eschenbach F; Institute of Medical Informatics, Charité - Universitätsmedizin Berlin, Germany.; Clinical Study Center, Berlin Institute of Health, Charité - Universitätsmedizin Berlin, Germany., Voge L; Institute of Medical Informatics, Charité - Universitätsmedizin Berlin, Germany., Ruhm L; Clinical Study Center, Berlin Institute of Health, Charité - Universitätsmedizin Berlin, Germany., Wagnitz J; Institute of Medical Informatics, Charité - Universitätsmedizin Berlin, Germany., Näher AF; Institute of Medical Informatics, Charité - Universitätsmedizin Berlin, Germany., Grünewald E; Institute of Medical Informatics, Charité - Universitätsmedizin Berlin, Germany., Nothacker J; Clinical Study Center, Berlin Institute of Health, Charité - Universitätsmedizin Berlin, Germany., von Kalle C; Clinical Study Center, Berlin Institute of Health, Charité - Universitätsmedizin Berlin, Germany., Kumpf O; Institute of Medical Informatics, Charité - Universitätsmedizin Berlin, Germany., Balzer F; Institute of Medical Informatics, Charité - Universitätsmedizin Berlin, Germany.
Source: Studies in health technology and informatics [Stud Health Technol Inform] 2026 May 21; Vol. 336, pp. 989-993.
Publication Type: Journal Article; Comparative Study
Journal Info: Publisher: IOS Press Country of Publication: Netherlands NLM ID: 9214582 Publication Model: Print Cited Medium: Internet ISSN: 1879-8365 (Electronic) Linking ISSN: 09269630 NLM ISO Abbreviation: Stud Health Technol Inform Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Frey+N%22">Frey N</searchLink>; Institute of Medical Informatics, Charité - Universitätsmedizin Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Meyer-Eschenbach+F%22">Meyer-Eschenbach F</searchLink>; Institute of Medical Informatics, Charité - Universitätsmedizin Berlin, Germany.; Clinical Study Center, Berlin Institute of Health, Charité - Universitätsmedizin Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Voge+L%22">Voge L</searchLink>; Institute of Medical Informatics, Charité - Universitätsmedizin Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Ruhm+L%22">Ruhm L</searchLink>; Clinical Study Center, Berlin Institute of Health, Charité - Universitätsmedizin Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Wagnitz+J%22">Wagnitz J</searchLink>; Institute of Medical Informatics, Charité - Universitätsmedizin Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Näher+AF%22">Näher AF</searchLink>; Institute of Medical Informatics, Charité - Universitätsmedizin Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Grünewald+E%22">Grünewald E</searchLink>; Institute of Medical Informatics, Charité - Universitätsmedizin Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Nothacker+J%22">Nothacker J</searchLink>; Clinical Study Center, Berlin Institute of Health, Charité - Universitätsmedizin Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22von+Kalle+C%22">von Kalle C</searchLink>; Clinical Study Center, Berlin Institute of Health, Charité - Universitätsmedizin Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Kumpf+O%22">Kumpf O</searchLink>; Institute of Medical Informatics, Charité - Universitätsmedizin Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Balzer+F%22">Balzer F</searchLink>; Institute of Medical Informatics, Charité - Universitätsmedizin Berlin, Germany.
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